Results 41 to 50 of about 1,009,765 (207)

ACETYLCHOLINE INJECTION CAUSES CORONARY ARTERY SPASM AND CORONARY ARTERY MICROCIRCULATION DYSFUNCTION—A CLINICAL RESEARCH [PDF]

Heart, 2012
Objectives Observing the patients with angina during the procedure acetylcholine causes coronary artery spasm, whether coronary artery microcirculation dysfunction is existed and surveying the influencing factor. Methods We studied the patients with
Yingjun Zhao, Na Zhang, Yingjun Zhao
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Invasive evaluation of coronary microvascular dysfunction [PDF]

, 2022
Coronary microvascular dysfunction (CMD) is a prevalent cause of ischemic heart disease and is associated with poorer quality of life and worse patient outcomes.
Travieso, Alejandro, Mejia-Rentería, Hernan, Mejía Rentería, Hernán David, Faria, Daniel, Jeronimo Baza, Adrian, Escaned Barbosa, Javier, Escaned, Javier, Jeronimo-Baza, Adrian, Shabbir, Asad, Adrian Jeronimo-Baza, Asad Shabbir, Javier Escaned, Alejandro Travieso, Hernan Mejia-Rentería, Daniel Faria   +14 more
core   +1 more source

Acute Rho-kinase inhibition improves coronary dysfunction in vivo, in the early diabetic microcirculation [PDF]

Cardiovascular Diabetology, 2013
Activation of RhoA/Rho-kinase (ROCK) is increasingly implicated in acute vasospasm and chronic vasoconstriction in major organ systems. Therefore we aimed to ascertain whether an increase in ROCK activity plays a role in the deterioration of coronary vascular function in early stage diabetes.Synchrotron radiation microangiography was used to determine ...
Pearson, JT, Jenkins, MJ, Edgley, AJ, Sonobe, T, Joshi, M, Waddingham, MT, Fujii, Y, Schwenke, DO, Tsuchimochi, H, Yoshimoto, M, Umetani, K, Kelly, DJ, Shirai, M   +12 more
openaire   +3 more sources

Evaluation of the coronary flow by the coronary clearance time in patients with cardiac syndrome X

Journal of International Medical Research, 2018
Objective The vessels involved in the microcirculation are too small to be visualized by conventional angiography and no tools are currently available that can directly evaluate the coronary microcirculation.
Erkan Yildirim, Uygar Cagdas Yuksel, Murat Celik, Baris Bugan, Mutlu Gungor, Yalcin Gokoglan, Mustafa Koklu, Suat Gormel, Salim Yasar, Cem Barcin   +9 more
doaj   +1 more source

Coronary Physiology: Delivering Precision Medicine?

Reviews in Cardiovascular Medicine, 2022
Coronary physiological assessment is now widely used to assess epicardial coronary lesions in cath lab. Based on clinical evidence, fractional flow reserve (FFR) is the gold standard method to select whether epicardial coronary lesions need ...
Laura Maitre-Ballesteros, Laurent Riou, Stephanie Marliere, Marjorie Canu, Estelle Vautrin, Nicola Piliero, Oliviez Ormezzano, Helene Bouvaist, Alexis Broisat, Catherine Ghezzi, Daniel Fagret, Gérald Vanzetto, Loïc Djaïleb, Gilles Barone-Rochette   +13 more
doaj   +1 more source

Coronary Microcirculatory Dysfunction. Diagnostic  approach [PDF]

Introduction: Angina pectoris affects more than 100 million people worldwide. Many of these patients present with angina with non-obstructive coronary arteries (ANOCA) or ischemia with non-obstructive coronary arteries (INOCA).
Rodríguez Hechavarría, Ramón Arturo, Jera Gonzalez, Javier, Turro Mesa, Lucia   +2 more
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Coronary Microcirculation and Ischemic Heart Disease, Today

, 2018
This article summarizes several contributions on the coronary microcirculation. Many of the participant authors belong to the Working Group on Coronary Pathophysiology and Microcirculation of European Society of Cardiology. These contributions explored a
Bugiardini, Raffaele
core   +1 more source

Ligustrazine prevents coronary microcirculation dysfunction in rats via suppression of miR-34a-5p and promotion of Sirt1

European Journal of Pharmacology, 2022
The coronary microembolization contributes to coronary microvascular dysfunction (CMD), in which miR-34a-5p may play a critical role. Ligustrazine has been reported to improve CMD. The present study was designed to discuss the role of miR-34a-5p/Sirt1 pathway in CMD and explore the underlying mechanism of ligustrazine.Coronary microembolization (CME ...
Jie, Gao, Junguo, Ren, Xin, Ma, Ying, Zhang, Lei, Song, Jianxun, Liu, Dazhuo, Shi, Xiaojuan, Ma   +7 more
openaire   +2 more sources

Ischemia with Nonobstructive Coronary Artery Disease and Atrial Cardiomyopathy—Two Sides of the Same Story?

Life, 2023
Ischemia with nonobstructive coronary artery disease (INOCA) is increasingly recognized as a significant cause of angina, myocardial remodeling, and eventually heart failure (HF). Coronary microvascular dysfunction (CMD) is a major endotype of INOCA, and
Irina Afrăsânie, Iulian Theodor Matei, Sabina Andreea Leancă, Adriana Chetran, Alexandru Dan Costache, Vlad-Adrian Afrăsânie, Bianca-Ana Dmour, Daniela Crișu, Minerva Codruța Bădescu, Lăcrămioara Ionela Șerban, Irina Iuliana Costache   +10 more
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Coronary Flow Velocity Reserve by Echocardiography: Beyond Atherosclerotic Disease

Diagnostics, 2023
Coronary flow velocity reserve (CFVR) is defined as the ratio between coronary flow velocity during maximal hyperemia and coronary flow at rest.
Giovanni Civieri, Roberta Montisci, Peter L. M. Kerkhof, Sabino Iliceto, Francesco Tona   +4 more
doaj   +1 more source