Results 21 to 30 of about 1,009,765 (207)

Effects of mineralocorticoid receptor antagonists on coronary microcirculation: a mini-review [PDF]

Frontiers in Cardiovascular Medicine
Mineralocorticoid receptor antagonists (MRAs) serve as a foundational therapies in the management of heart failure, hypertension, and chronic kidney disease.
Yu Li, Zhenhong Zhang
doaj   +2 more sources

Coronary Microvascular Dysfunction: Pathophysiology, Clinical Phenotypes, and Mechanism-Guided Diagnostic Strategies [PDF]

Journal of Cardiovascular Development and Disease
Coronary microvascular dysfunction (CMD) is a prevalent and clinically important cause of myocardial ischemia across the spectrum of coronary artery disease, including patients with angina and nonobstructive coronary arteries, persistent symptoms after ...
Divyansh Sharma, Daniel Bishev, Shudipan Chakraborty, Michael V. DiCaro, Ryan Shao, KiBuom Lee, KaChon Lei, Omar Shah, Sanjay Malhotra, Chowdhury Ahsan   +9 more
doaj   +2 more sources

Diffusely impaired myocardial perfusion in patients with suspected coronary artery disease: Clinical utility of relative perfusion [PDF]

Clinical Physiology and Functional Imaging, Volume 46, Issue 6, November 2026.
Abstract Background In patients with suspected coronary artery disease (CAD), diffusely impaired hyperaemic myocardial blood flow (MBF) may indicate a multivessel epicardial CAD but also impaired coronary microcirculation. We assessed whether relative hyperaemic MBF—that is, the ratio of the lowest to the highest regional hyperaemic MBF—predicts ...
Niklas Vartiainen, Antti‐Pekka E. Rissanen, Suvi Hartikainen, Svantte Halttunen, Aleksi J. Leikas, Elina Kariniemi, Eero Strengell, Paavo‐Ilari Kuikka, Juha E. K. Hartikainen, Tomi P. Laitinen   +9 more
wiley   +2 more sources

ESC Working Group on Coronary Pathophysiology and Microcirculation position paper on `coronary microvascular dysfunction in cardiovascular disease'

, 2020
Although myocardial ischaemia usually manifests as a consequence of atherosclerosis-dependent obstructive epicardial coronary artery disease, a significant percentage of patients suffer ischaemic events in the absence of epicardial coronary artery obstruction.
Padro, Teresa, Manfrini, Olivia, Bugiardini, Raffaele, Canty, John, Cenko, Edina, De Luca, Giuseppe, Duncker, Dirk J., Eringa, Etto C., Koller, Akos, Tousoulis, Dimitris, Trifunovic, Danijela, Vavlukis, Marija, de Wit, Cor, Badimon, Lina   +15 more
openaire   +2 more sources

Invasive coronary physiology in patients with angina and non-obstructive coronary artery disease: a consensus document from the coronary microvascular dysfunction workstream of the British Heart Foundation/National Institute for Health Research Partnership [PDF]

, 2022
Nearly half of all patients with angina have non-obstructive coronary artery disease (ANOCA); this is an umbrella term comprising heterogeneous vascular disorders, each with disparate pathophysiology and prognosis.
Rahman, H., Hoole, S.P., Channon, K., UK Coronary Microvascular Dysfunction Working Group, Morris, Paul D, Kharbanda, Rajesh K, Divaka Perera, Channon, K, Petraco, Ricardo, Haseeb Rahman, Hoole, SP, Perera, D., Sinha, Aish, Ricardo Petraco, Keith Channon, Colin Berry, Paul D Morris, Channon, Keith, Stephen P Hoole, Morris, P.D., Hoole, Stephen P, Rajesh K Kharbanda, Rahman, Haseeb, Kharbanda, RK, Hoole, Stephen P., Kharbanda, R.K., Aish Sinha, Petraco, R, Kharbanda, Rajesh K., Perera, Divaka, Sinha, A., Morris, Paul D., Berry, Colin, Berry, C, Morris, PD, Berry, C., Perera, D, Sinha, A, Petraco, R., Rahman, H   +39 more
core   +1 more source

Coronary microvascular dysfunction is associated with impaired cognitive function: the Cerebral-Coronary Connection study (C3 study) [PDF]

, 2022
Background It remains unknown whether the presence of coronary microcirculatory dysfunction (CMD) correlates with its equivalent conditionin the brain, cerebral small vessel disease (CSVD).
de Diego, Jose Juan Gomez, Espejo-Paeres, Carolina, Bustos García De Castro, Ana María, Escaned, Javier, Modrego Martín, Javier, Delgado Álvarez, Alfonso, Gómez-Escalonilla, Carlos Ignacio, Gómez Garre, María Dulce Nombre, Pérez De Isla, Leopoldo, Ortega-Hernandez, Adriana, Mejía Rentería, Hernán, Matías-Guiu, Jordi A, Bustos, Ana, Yus, Miguel, Arrazola García, Juan Lorenzo, Reneses Prieto, Blanca María Asunción, Mejia-Renteria, Hernan, Reneses-Prieto, Blanca, Gómez de Diego, José Juan, Ortega Hernández, Adriana, Modrego-Martin, Javier, Finocchiaro, Francesca, Fernández, Sara, Escaned Barbosa, Javier, Arrazola-García, Juan, Gómez-Garré, Maria Dulcenombre, Matías-Guiu Guía, Jorge, Matías-Guiu, Jorge, Espejo Paeres, Carolina, Travieso, Alejandro, Delgado-Alvarez, Alfonso, Papadopoulos, Petros, Fernández Guinea, Sara Belén   +32 more
core   +1 more source

Findings suggestive of coronary microvascular dysfunction in cats with myocardial ischemia [PDF]

Open Veterinary Journal, 2021
Background: Myocardial infarction is an important cause of death and disability among humans worldwide. Few studies have reported the occurrence of myocardial infarction in small animals as well.
Guillermo Belerenian, Pablo Alejandro Donati, Cristian Daniel Rodriguez, Victor Castillo, Juan Manuel Guevara, Claudia Pucheta, Sergio Ferraris, Roberto Walter Israel Olivares   +7 more
doaj   +1 more source

Microcirculation function assessment in acute myocardial infarction: A systematic review of microcirculatory resistance indices

Frontiers in Cardiovascular Medicine, 2022
BackgroundUp to 50% of acute myocardial infarction (MI) patients present with microvascular dysfunction, after a successful percutaneous coronary intervention (PCI), which leads to worse clinical outcomes.
Marta Silva, Luis Paiva, Luis Paiva, Luis Paiva, Rogério Teixeira, Rogério Teixeira, Rogério Teixeira, Maria João Ferreira, Maria João Ferreira, Maria João Ferreira, Lino Gonçalves, Lino Gonçalves, Lino Gonçalves   +12 more
doaj   +1 more source

Pathophysiological factors contributing to fractional flow reserve and instantaneous wave-free ratio discordance [PDF]

Reviews in Cardiovascular Medicine, 2022
The diagnostic accuracy and clinical benefits of instantaneous wave-free ratio (iFR) compared to fractional flow reserve (FFR) have been well-established in the literature. Despite the advantages of non-hyperemic pressure indices, approximately 20% of
Benjamin Fogelson, Hassan Tahir, James Livesay, Raj Baljepally   +3 more
doaj   +1 more source

Coronary Microvascular Angina: A State-of-the-Art Review

Frontiers in Cardiovascular Medicine, 2022
Up to 60–70% of patients, undergoing invasive coronary angiography due to angina and demonstrable myocardial ischemia with provocative tests, do not have any obstructive coronary disease. Coronary microvascular angina due to a dysfunction of the coronary
Francesco Spione, Francesco Spione, Victor Arevalos, Rami Gabani, Manel Sabaté, Salvatore Brugaletta   +5 more
doaj   +1 more source