Results 11 to 20 of about 1,009,765 (207)

ESC Working Group on Coronary Pathophysiology and Microcirculation position paper on ‘coronary microvascular dysfunction in cardiovascular disease’ [PDF]

Cardiovascular Research, 2020
Abstract Although myocardial ischaemia usually manifests as a consequence of atherosclerosis-dependent obstructive epicardial coronary artery disease, a significant percentage of patients suffer ischaemic events in the absence of epicardial coronary artery obstruction.
Teresa Padro, Olivia Manfrini, Raffaele Bugiardini, John Canty, Edina Cenko, Giuseppe De Luca, Dirk J Duncker, Etto C Eringa, Akos Koller, Dimitris Tousoulis, Danijela Trifunovic, Marija Vavlukis, Cor de Wit, Lina Badimon   +13 more
core   +13 more sources

Coronary microvascular dysfunction in heart failure patients [PDF]

Frontiers in Cardiovascular Medicine, 2023
Coronary microcirculation has multiple layers of autoregulatory function to maintain resting flow and augment hyperemic flow in response to myocardial demands.
Takumi Toya, Yuji Nagatomo, Yukinori Ikegami, Nobuyuki Masaki, Takeshi Adachi   +4 more
doaj   +2 more sources

Effect of sodium-glucose Co-transporter 2 inhibitors on coronary microcirculation [PDF]

Frontiers in Pharmacology
Coronary microvascular disease (CMVD) has emerged as a new target for the occurrence and development of heart failure treatment. Various indicators such as Index of Microvascular Resistance, Coronary Flow Reserve, Microvascular Resistance Reserve ...
Shaoxin Chen, Weiqian Ou, Shuguang Gan, Lixian Chen, Baohua Liu, Zhenhong Zhang   +5 more
doaj   +2 more sources

The effectiveness of alprostadil in treating coronary microcirculation dysfunction following ST‑segment elevation myocardial infarction in a pig model [PDF]

Experimental and Therapeutic Medicine, 2021
Though alprostadil has been reported to improve the impaired microcirculation of patients with pulmonary arterial hypertension, its effectiveness as a treatment for coronary microvasculature dysfunction (CMD) following ST-segment elevation myocardial infarction (STEMI) is unknown.
Duan, Tianbing, Zhang, Jinxia, Kong, Ranran, Song, Rui, Huang, Weilong, Xiang, Dingcheng   +5 more
openaire   +4 more sources

Patogênese, Avaliação e Tratamento da Disfunção da Microcirculação Coronariana [PDF]

Arquivos Brasileiros de Cardiologia
Resumo A doença cardiovascular é a causa predominante de mortalidade em escala global. A pesquisa indica que as mulheres, em comparação aos homens, apresentam maior probabilidade de apresentar doença arterial coronariana (DAC) não obstrutiva quando têm sintomas de isquemia miocárdica.
Bing Ji, Xue-Bo Liu
openaire   +5 more sources

The association between coronary microvascular dysfunction and HbA1c in patients with unstable angina pectoris [PDF]

Frontiers in Cardiovascular Medicine
BackgroundAngiographic microvascular resistance (AMR) is an effective parameter for assessing coronary microcirculatory function, and studies have indicated its association with adverse cardiovascular outcomes.
Kangming Li, Jing Wang, Shuang Liu, Shuang Liu, Chunmei Qi, Chunmei Qi   +5 more
doaj   +2 more sources

Coronary microvascular dysfunction in childhood: An emerging pathological entity and its clinical implications [PDF]

American Heart Journal Plus
Coronary microvascular dysfunction (CMD) encompasses a spectrum of structural and functional alterations in coronary microvasculature resulting in impaired coronary blood flow and consequent myocardial ischemia without obstruction in epicardial coronary ...
Takeshi Tsuda, Gina Patel
doaj   +2 more sources

Ubiquitination regulation in coronary microcirculation dysfunction: focus on the endothelial cells [PDF]

Frontiers in Cardiovascular Medicine
Basic and clinical research on coronary microvascular disease (CMD) has spanned half a century. As a pathogenesis independent of epicardial coronary stenosis, CMD has become a major hotspot in cardiovascular medicine.
Qingying Zhang, Qingying Zhang, Qingying Zhang, Tingting Wang, Tingting Wang, Tingting Wang, Siyu Wang, Siyu Wang, Siyu Wang, Yushan Chen, Yushan Chen, Yiwen Sheng, Yiwen Sheng, Yiwen Sheng, Haodi Zhang, Haodi Zhang, Haodi Zhang, Yunhao Wang, Yunhao Wang, Yunhao Wang, Boyuan Jin, Boyuan Jin, Boyuan Jin, Chengjun Hua, Chengjun Hua, Chengjun Hua, Xinyi Han, Xinyi Han, Xinyi Han   +28 more
doaj   +2 more sources

Vasomotor Regulation of Coronary Microcirculation by Oxidative Stress: Role of Arginase [PDF]

Frontiers in Immunology, 2013
Overproduction of reactive oxygen species, i.e., oxidative stress, is associated with the activation of redox signaling pathways linking to inflammatory insults and cardiovascular diseases by impairing endothelial function and consequently blood flow ...
Lih eKuo, Lih eKuo, Lih eKuo, Travis eHein, Travis eHein   +4 more
doaj   +2 more sources

Coronary Microcirculation in Aortic Stenosis: Pathophysiology, Invasive Assessment, and Future Directions

Journal of Interventional Cardiology, 2020
With the increasing prevalence of aortic stenosis (AS) due to a growing elderly population, a proper understanding of its physiology is paramount to guide therapy and define severity.
Jo M. Zelis, Pim A. L. Tonino, Nico H. J. Pijls, Bernard De Bruyne, Richard L. Kirkeeide, K. Lance Gould, Nils P. Johnson   +6 more
doaj   +2 more sources