Results 141 to 150 of about 3,564,139 (354)
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The MT‐ATP6 gene m.8993T>G pathogenic variant has been associated with Leigh syndrome, especially in patients exhibiting a high degree of heteroplasmy. Although patients may present with a wide phenotypic spectrum, characteristic findings include bilateral, symmetric hyperintensities in the basal ganglia and brainstem on brain MRI ...
Ramya Treitel +2 more
wiley +1 more source
Tracking COVID-19 by Tracking Infectious Trajectories [PDF]
arXiv, 2020 Nowadays, the coronavirus pandemic has and is still causing large numbers of deaths and infected people. Although governments all over the world have taken severe measurements to slow down the virus spreading (e.g., travel restrictions, suspending all sportive, social, and economic activities, quarantines, social distancing, etc.), a lot of persons ...
arxiv
Australian Journal of Social Issues, EarlyView.ABSTRACT During the COVID‐19 pandemic, disruptions to finances and relationships were significant. Analysing Australian longitudinal survey data from May 2020 and August 2021, this study examines the Family Stress Model, which posits that financial stress influences relational dynamics within households.
Azadeh Abbasi Shavazi +2 more
wiley +1 more source
Antiviral effects and mechanism of Qi pi pill against influenza viruses
Animal Models and Experimental Medicine, EarlyView.Qi pi pill presents anti‐influenza effect and inhibits viral replication in vitro by targeting both the viral RNA replication and the release of new viral particles. Furthermore, QPP modulates the production of proinflammatory cytokines induced by influenza infection in host cells.
Chengcheng Zhang +10 more
wiley +1 more source
Coronavirus infections in veterinary medicine [PDF]
, 2005 The evidence that the “SARS-virus” could be an animal coronavirus and/or could originate from an animal coronavirus has increased the level of interest for coronavirus infections in animals. It was reported during the outbreak of SARS that researchers from HongKong University examined 25 animals representing eight species in a live animal market in ...
Olaf Weber, Axel Schmidt
openaire +2 more sources
Respiratory virus mRNA vaccines: mRNA Design, clinical studies, and future challenges
Animal Models and Experimental Medicine, EarlyView.Abstract Respiratory infectious diseases frequently erupt on a global scale, with RNA viruses, such as SARS‐CoV‐2, RSV, and influenza viruses, posing challenges to vaccine development due to their high mutation rates. Traditional vaccine development cycles are lengthy and struggle to keep pace with rapidly evolving viruses, whereas messenger RNA (mRNA)
Linlin Zheng, Han Feng
wiley +1 more source
Brazilian Oral Research: The aim of this study was to evaluate the knowledge of and attitudes toward coronavirus disease 2019 (COVID-19) among the parents of child dental patients in Shenzhen during the outbreak. A structured questionnaire containing 10 questions was used, and
Jin Sun, Yan Xu, Qian Qu, Wei Luo
doaj +1 more source
Comparison of the pathogenicity of multiple SARS‐CoV‐2 variants in mouse models
Animal Models and Experimental Medicine, EarlyView.We assessed the pathogenicity of various SARS‐CoV‐2 variants using two distinct mouse models. Our findings indicated that earlier variants, including WH‐09, Beta, and Delta, exhibited greater pathogenicity than later variants. Specifically, the Omicron variant demonstrated reduced pathogenicity, characterized by a shorter disease course and diminished ...
Qi Lv +12 more
wiley +1 more source
Modeling the molecular impact of SARS-CoV-2 infection on the renin-angiotensin system [PDF]
arXiv, 2020 SARS-CoV-2 coronavirus infection is mediated by the binding of its spike protein to the angiotensin-converting enzyme 2 (ACE2), which plays a pivotal role in the renin-angiotensin system (RAS). The study of RAS dysregulation due to SARS-CoV-2 infection is fundamentally important for a better understanding of the pathogenic mechanisms and risk factors ...
arxiv
Novel coronavirus infection and pregnancy [PDF]
Ultrasound in Obstetrics & Gynecology, 2020 Yang, H., Wang, C., Poon, L. C.
openaire +3 more sources