Results 141 to 150 of about 482,781 (345)

Coronavirus infection of polarized epithelial cells

open access: yesTrends in Microbiology, 1995
Epithelial cells are the first host cells to be infected by incoming c oronaviruses. Recent observations in vitro show that coronaviruses are released from a specific side of these polarized cells, and this polarized release might be important for the spread of the infection in vivo.
Horzinek, M.C.   +2 more
openaire   +5 more sources

B cells and systemic sclerosis interstitial lung disease

open access: yesArthritis &Rheumatology, Accepted Article.
Interstitial lung disease is an important complication of systemic sclerosis (SSc‐ILD) with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to FDA‐approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of interstitial lung diseases of other systemic autoimmune ...
Nina Goldman   +2 more
wiley   +1 more source

Serum cytokine profiling differentiates underlying diseases in cytokine storm syndrome

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Cytokine storm syndrome (CSS), commonly associated with hemophagocytic lymphohistiocytosis (HLH), is a fatal hyperinflammatory syndrome. Differentiating the underlying diseases responsible for CSS is essential for timely therapeutic decisions. This study explored the clinical usefulness of serum cytokine profiling in distinguishing underlying
Shuya Kaneko   +42 more
wiley   +1 more source

Oral manifestations in patients with COVID-19 treated in an isolation center in Las Tunas

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2021
Background: oral manifestations associated with COVID-19 patients may appear prior to respiratory symptoms, during and after the course of the disease.Objective: to describe the oral manifestations in patients with COVID-19 treated at the “Los Cocos ...
Taimí Santos-Velázquez   +1 more
doaj  

Essential work, invisible workers: The role of digital curation in COVID‐19 Open Science

open access: yesJournal of the Association for Information Science and Technology, Volume 76, Issue 4, Page 703-717, April 2025.
Abstract In this paper, we examine the role digital curation practices and practitioners played in facilitating open science (OS) initiatives amid the COVID‐19 pandemic. In Summer 2023, we conducted a content analysis of available information regarding 50 OS initiatives that emerged—or substantially shifted their focus—between 2020 and 2022 to address ...
Irene V. Pasquetto   +2 more
wiley   +1 more source

The issues caused by misinformation—How workers and organizations deal with it: A systematic literature review. An Annual Review of Information Science and Technology (ARIST) paper

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract In today's digital age, misinformation propagates rapidly through digital channels, blurring the lines between truth and fiction, and challenging the foundations of trust in information sources. Although affecting all spheres of life, misinformation poses a significant threat to workers highlighting a critical intersection between ...
Ashwani Malhotra   +4 more
wiley   +1 more source

Harnessing chimeric antigen receptor macrophages against solid tumors

open access: yesCancer Communications, EarlyView.
Abstract Macrophages are prevalent in multiple tumors and exhibit diverse and potent functional activities. Therapeutic reprogramming of macrophage phenotypes represents a promising strategy for cancer immunotherapy. Engineering chimeric antigen receptors (CARs) to endow macrophages with anti‐tumor capacities demonstrated encouraging efficacy ...
Mengru Wang   +3 more
wiley   +1 more source

Chemically Synthesized LRAD3‐D1 Interacts with N‐Terminal Domain of SARS‐CoV‐2 Spike Protein

open access: yesChemBioChem, EarlyView.
Chemical synthesis, calcium‐templated in‐vitro folding and competitive ELISA assay reveal that only domain 1 of the LRAD3 ectodomain interacts with the severe acute respiratory syndrome‐related corona virus 2 (SARS‐CoV‐2) spike NTD, while domains 2 and 3 do not, providing valuable insight into ACE2‐independent viral entry pathways that may contribute ...
Mrinmoy Jana   +5 more
wiley   +1 more source

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