Results 251 to 260 of about 1,203,995 (286)

Correlative light–electron microscopy

2011
Recent advances in combining light and electron microscopy imaging techniques provide the means to correlate dynamic biological processes with the underlying structural correlates in situ. In this chapter, we provide snapshots of current advances targeting quantitative correlation of the dynamic state of a biological pathway with high-resolution ...
Dorit, Hanein, Niels, Volkmann
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Correlative Microscopy in Pathology

Proceedings, annual meeting, Electron Microscopy Society of America, 1996
Microscopy has always provided important anatomical and structural information for biologists and clinicians. The amount of information available has increased exponentially as a result of recent advances in light microscopy, immunohistochemistry, in situ hybridization, electron microscopy, and microprobe analysis.
D. N. Howell, S. E. Miller, E.A. LeFurgey, P. Ingram, J.D. Shelburne   +4 more
openaire   +1 more source

Correlation mapping microscopy

SPIE Proceedings, 2015
Changes in the microcirculation are associated with conditions such as Raynauds disease. Current modalities used to assess the microcirculation such as nailfold capillaroscopy are limited due to their depth ambiguity. A correlation mapping technique was recently developed to extend the capabilities of Optical Coherence Tomography to generate depth ...
James McGrath, Sergey Alexandrov, Peter Owens, Hrebesh M. Subhash, Martin J. Leahy   +4 more
openaire   +1 more source

Correlative Single-Molecule Localization Microscopy and Confocal Microscopy

2017
Single-molecule localization microscopy allows the ability to image fluorescence labeled molecular targets at nanoscale resolution. However, for many biological questions the ability to provide tissue and cellular context in addition to these high resolution data is eminently informative.
Christian, Soeller, Yufeng, Hou, Isuru D, Jayasinghe, David, Baddeley, David, Crossman   +4 more
openaire   +2 more sources

Correlative Light and Electron Microscopy of Autophagosomes

2019
Live-cell imaging has been widely used to study autophagosome biogenesis and maturation. When combined with correlative electron microscopy, this approach can be extended to reveal ultrastructural details in three dimensions. The resolution of electron microscopy is needed when membrane contact sites and tubular connections between organelles are ...
Sigurdur, Gudmundsson, Jenny, Kahlhofer, Nastassia, Baylac, Katri, Kallio, Eeva-Liisa, Eskelinen   +4 more
openaire   +2 more sources

Markers for Correlated Light and Electron Microscopy

2007
Publisher Summary This chapter reviews whole cell, organelle, and protein labeling methods for correlated observations in the spatial domains of both light microscopy (LM) and electron microscopy (EM). The combination of EM tomographic reconstructions with labeling of specific components provides a powerful method for localizing proteins within their
Sosinsky, Gina E, Giepmans, Ben N G, Deerinck, Thomas J, Gaietta, Guido M, Ellisman, Mark H   +4 more
openaire   +3 more sources

Correlative Microscopy and Spectroscopy Workflow for Microplastics

Applied Spectroscopy, 2020
Microplastics (MPs) have been reported in various environmental compartments and their number is continuously increasing because of degradation into smaller fragments down to nanoplastics. Humans are exposed to these small-sized MPs through food and air with potential health consequences that still need to be determined.
Sarau, George, Kling, Lasse, Oßmann, Barbara E., Unger, Ann-Katrin, Vogler, Frank, Christiansen, Silke H.   +5 more
openaire   +2 more sources

Correlated Light and Electron Cryo-Microscopy

2010
Light and electron cryo-microscopy have each proven to be powerful tools to study biological structures in a near-native state. Light microscopy provides important localization information, while electron microscopy provides the resolution necessary to resolve fine structural details.
Briegel, A., Chen, S.Y., Koster, A.J., Plitzko, J.M., Schwartz, C.L., Jensen, G.J.   +5 more
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Correlative microscopy of enamel prism orientation

American Journal of Anatomy, 1975
AbstractBoth mature and developing human enamel were studied by correlative light and electron microscopic techniques. Ordinary light microscopic observations of routinely prepared ground sections produced a totally inaccurate impression of enamel prism direction. In contrast, ground sections which were acid‐etched and viewed with phase contrast optics,
D F, Weber, P L, Glick
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Correlative Video Light/Electron Microscopy

Current Protocols in Cell Biology, 2001
AbstractThis unit describes newly developed methods that allow the examination of living cells by time‐lapse analysis with the subsequent identification of the just‐observed organelle under an electron microscope. To understand how such cellular functions, such as intracellular traffic, cytokinesis, and cell migration, are organized and executed in ...
R S, Polishchuk, A A, Mironov
openaire   +2 more sources