Human gut Bacteroides capture vitamin B12 via cell surface-exposed lipoproteins [PDF]
eLife, 2018 Human gut Bacteroides use surface-exposed lipoproteins to bind and metabolize complex polysaccharides. Although vitamins and other nutrients are also essential for commensal fitness, much less is known about how commensal bacteria compete with each other
Aaron G Wexler +5 more
doaj +3 more sources
Axial Ligation and Redox Changes at the Cobalt Ion in Cobalamin Bound to Corrinoid Iron-Sulfur Protein (CoFeSP) or in Solution Characterized by XAS and DFT. [PDF]
PLoS ONE, 2016 A cobalamin (Cbl) cofactor in corrinoid iron-sulfur protein (CoFeSP) is the primary methyl group donor and acceptor in biological carbon oxide conversion along the reductive acetyl-CoA pathway.
Peer Schrapers +6 more
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Sister Dehalobacter Genomes Reveal Specialization in Organohalide Respiration and Recent Strain Differentiation Likely Driven by Chlorinated Substrates [PDF]
Frontiers in Microbiology, 2016 The genomes of two closely related Dehalobacter strains (strain CF and strain DCA) were assembled from the metagenome of an anaerobic enrichment culture that reductively dechlorinates chloroform (CF), 1,1,1-trichloroethane (1,1,1-TCA) and 1,1 ...
Shuiquan eTang +6 more
doaj +2 more sources
Vitamin B12 and Reproductive Health: Clinical Insights, Emerging Mechanistic Understanding, and Nutritional Aspects. [PDF]
Mol Reprod DevABSTRACT Epidemiological data from assisted reproductive technologies (ART) link vitamin B12 (VitB12) deficiency to shorter gestation, low birth weight, and reduced live birth rates. VitB12 also plays a critical role in fertility for both sexes by supporting gamete quality.
Mathew AR +8 more
europepmc +2 more sources
Pseudovitamin B<sub>12</sub> producing Loigolactobacillus coryniformis enhances soy milk fermentation by Lactobacillus delbrueckii subsp. bulgaricus. [PDF]
J Sci Food AgricAbstract BACKGROUND Fermenting soy milk with lactic acid bacteria is challenging. Generally, carbohydrates are added to enhance the acid production in soy milk. However, the yoghurt starter Lactobacillus delbrueckii subsp. bulgaricus did not succeed in fermenting soy milk supplemented with carbohydrates.
Tsuda H, Iwai K, Hayashizaki N.
europepmc +2 more sources
Evidence for corrin biosynthesis in the last universal common ancestor. [PDF]
FEBS JCobalamin biosynthesis can be traced back to the last universal common ancestor. After a stage of chemical evolution of the acetyl‐CoA pathway, the enzymatic synthesis of cobalamin evolved, allowing life to be independent of the insoluble solid‐state catalysts that tethered primordial CO2 assimilation to the Earth's crust, suggesting a role for corrin ...
Modjewski LD +5 more
europepmc +2 more sources
Expansion of cagA Copy Number in Helicobacter pylori During Co-Infection in a Mouse Model. [PDF]
HelicobacterABSTRACT Introduction The virulence factor CagA is critical in mediating inflammation, and Helicobacter pylori PMSS1 dynamically modulates cagA copy number in response to host immune pressure. Co‐infection with Salmonella enterica serotype Typhimurium has been shown to heighten systemic inflammation and reduce H.
Tissera K +7 more
europepmc +2 more sources
Identification of specific corrinoids reveals corrinoid modification in dechlorinating microbial communities [PDF]
Environmental Microbiology, 2014 Summary Cobalamin and other corrinoids are essential cofactors for many organisms. The majority of microbes with corrinoid‐dependent enzymes do not produce corrinoids de novo , and instead must acquire corrinoids produced by other organisms in their environment. However, the
Men, Yujie +6 more
openaire +4 more sources
Four families of folate-independent methionine synthases.
PLoS Genetics, 2021 Although most organisms synthesize methionine from homocysteine and methyl folates, some have "core" methionine synthases that lack folate-binding domains and use other methyl donors.
Morgan N Price +2 more
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Water Science and Technology, 2022 Complete dechlorination of trichloroethene (TCE) by Dehalococcoides mccartyi is catalyzed by reductive dehalogenases (RDases), which possess cobalamin as the crucial cofactor. However, virtually all D. mccartyi isolated thus far are corrinoid auxotrophs.
Haijun Li +4 more
doaj +1 more source