Identification of specific corrinoids reveals corrinoid modification in dechlorinating microbial communities. [PDF]
Environmental Microbiology, 2015 Summary Cobalamin and other corrinoids are essential cofactors for many organisms. The majority of microbes with corrinoid‐dependent enzymes do not produce corrinoids de novo , and instead must acquire corrinoids produced by other organisms in their environment. However, the
Y. Men +6 more
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Corrinoid salvaging and cobamide remodeling in bacteria and archaea. [PDF]
J BacteriolCobamides (Cbas) are cobalt-containing cyclic tetrapyrroles used by cells from all domains of life as co-catalyst of diverse reactions. There are several structural features that distinguish Cbas from one another.
Villa EA, Escalante-Semerena JC.
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Laboratory evolution of E. coli with a natural vitamin B12 analog reveals roles for cobamide uptake and adenosylation in methionine synthase-dependent growth [PDF]
Journal of BacteriologyBacteria encounter chemically similar nutrients in their environment, which impact their growth in distinct ways. Among such nutrients are cobamides, the structurally diverse family of cofactors related to vitamin B12 (cobalamin), which function as ...
Kenny C. Mok +3 more
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Structural Basis for Universal Corrinoid Recognition by the Cobalamin Transport Protein Haptocorrin* [PDF]
Journal of Biological Chemistry, 2013 Background: Haptocorrin (HC) is a cobalamin (Cbl) transport protein known to recognize a wide range of corrinoids. Results: We solved the crystal structure of human HC in complex with Cbl and cobinamide.
Evelyne Furger +4 more
semanticscholar +2 more sources
Dalton Transactions, 2016 Myoglobin reconstituted with a cobalt tetradehydrocorrin derivative, rMb(Co(TDHC)), was investigated as a hybrid model to replicate the reaction catalyzed by methionine synthase.
Y. Morita +8 more
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Methanogenic activities signatures in broilers fed black soldier fly (Hermetia illucens) larvae-based diets [PDF]
Biochemistry and Biophysics ReportsMethanogenic archaea in the avian gut contribute to hydrogen turnover and thus play a role in fermentative efficiency and greenhouse gas emission. While black soldier fly larvae meal (BSFLM) has been explored as a replacement for fishmeal in broiler ...
Deborah Oluwaferanmi Ibiwoye +6 more
doaj +2 more sources
Versatility in Corrinoid Salvaging and Remodeling Pathways Supports Corrinoid-Dependent Metabolism in Dehalococcoides mccartyi [PDF]
Applied and Environmental Microbiology, 2012 ABSTRACTCorrinoids are cobalt-containing molecules that function as enzyme cofactors in a wide variety of organisms but are produced solely by a subset of prokaryotes. Specific corrinoids are identified by the structure of their axial ligands. The lower axial ligand of a corrinoid can be a benzimidazole, purine, or phenolic compound. Though it is known
S. Yi +6 more
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Influence of corrinoid antagonists on methanogen metabolism [PDF]
Journal of Bacteriology, 1981 Iodopropane inhibited cell growth and methane production when Methanobacterium thermoautotrophicum, Methanobacterium formicicum, and Methanosarcina barkeri were cultured on H2-CO2. Iodopropane (40 microM) inhibited methanogenesis (30%) and growth (80%) when M. barkeri was cultured mixotrophically on H2-CO2-methanol.
William R. Kenealy, J. G. Zeikus
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Sister Dehalobacter Genomes Reveal Specialization in Organohalide Respiration and Recent Strain Differentiation Likely Driven by Chlorinated Substrates [PDF]
Frontiers in Microbiology, 2016 The genomes of two closely related Dehalobacter strains (strain CF and strain DCA) were assembled from the metagenome of an anaerobic enrichment culture that reductively dechlorinates chloroform (CF), 1,1,1-trichloroethane (1,1,1-TCA) and 1,1 ...
Shuiquan eTang +6 more
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Genomic potential for mercury biotransformation in marine sediments across marginal slope to hadal zone [PDF]
Nature CommunicationsMercury accumulates in the deep sea, but its ecological impact on deep-sea ecosystems remains poorly understood. We conduct an analysis of 32 sediment cores, comprising 101 layers for the study of metagenomes, and additional 41 global reference sediment ...
Zhuobo Li +5 more
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