Results 61 to 70 of about 3,608 (195)

Navigating Transition Metal‐Dependent Cell Death: Mechanisms, Crosstalk, and Future Directions

open access: yesAdvanced Science, Volume 12, Issue 46, December 11, 2025.
Transition metals trigger distinct regulated cell death pathways beyond traditional apoptosis. This review examines ferroptosis (iron‐catalyzed lipid peroxidation) and cuproptosis (copper‐induced mitochondrial proteotoxicity), while exploring hypothetical “cobaltosis” as a novel pathway.
Qinghang Song, Yuxuan Yang, Lina Yang
wiley   +1 more source

Cobalamin‐Dependent Aryl Methyl Ether O‐Demethylases: Promising Enzymes for Biocatalytic Applications from Lignin Valorization to Organic Synthesis

open access: yesChemCatChem, Volume 17, Issue 21, November 10, 2025.
Cobalamin‐dependent aryl methyl ether O‐demethylases have high potential for biocatalytic applications, including lignin valorization and synthetic chemistry. In this review, we provide a detailed overview of such O‐demethylase systems identified to date from various microorganisms, including their mechanism, substrate scope and selectivity, and ...
Niels Krabbe Johnsen   +4 more
wiley   +1 more source

Identification of an Active Site-bound Nitrile Hydratase Intermediate through Single Turnover Stopped-flow Spectroscopy [PDF]

open access: yes, 2013
Stopped-flow kinetic data were obtained for the iron-type nitrile hydratase from Rhodococcus equi TG328-2 (ReNHase) using methacrylonitrile as the substrate.
Gumataotao, Natalie   +3 more
core   +2 more sources

Anaerobic Limonene Metabolism in a Methanogenic Enrichment Involves a Glycine Radical Enzyme

open access: yesEnvironmental Microbiology, Volume 27, Issue 11, November 2025.
A methanogenic enrichment culture on the natural monoterpene limonene is characterised by a novel glycine radical enzyme for anaerobic hydrocarbon activation, the presence of a microbial loop for necromass utilisation and the presence of a predator of Bacteria and Archaea. ABSTRACT Limonene is a natural monoterpene omnipresent in human environments. It
Almud Lonsing   +6 more
wiley   +1 more source

Novel molecular markers for the detection of methanogens and phylogenetic analyses of methanogenic communities

open access: yesFrontiers in Microbiology, 2015
Methanogenic Archaea produce approximately one billion tons of methane annually, but their biology remains largely unknown. This is partially due to the large phylogenetic and phenotypic diversity of this group of organisms, which inhabit various anoxic ...
Lukasz eDziewit   +9 more
doaj   +1 more source

Comparative metagenomics of three Dehalococcoides-containing enrichment cultures: the role of the non-dechlorinating community

open access: yesBMC Genomics, 2012
Background The Dehalococcoides are strictly anaerobic bacteria that gain metabolic energy via the oxidation of H2 coupled to the reduction of halogenated organic compounds. Dehalococcoides spp.
Hug Laura A   +4 more
doaj   +1 more source

A Mechanochemical Switch to Control Radical Intermediates [PDF]

open access: yes, 2014
B12-dependent enzymes employ radical species with exceptional prowess to catalyze some of the most chemically challenging, thermodynamically unfavorable reactions.
Brunk, Elizabeth   +3 more
core   +6 more sources

Microbial demethylation of dimethylsulfoniopropionate and methylthiopropionate [PDF]

open access: yes, 2000
As discussed in chapter 1 , there is an increased interest in the production of certain natural sulfur-containing flavor compounds or flavor precursors.
Jansen, Michael,
core   +3 more sources

Diverse reductive dehalogenases are associated with Clostridiales-enriched microcosms dechlorinating 1,2-dichloroethane [PDF]

open access: yes, 2015
The achievement of successful biostimulation of active microbiomes for the cleanup of a polluted site is strictly dependent on the knowledge of the key microorganisms equipped with the relevant catabolic genes responsible for the degradation process.
Balloi, Annalisa   +8 more
core   +5 more sources

Evolutionary Trajectories of Methionine Metabolism in Mycobacterium and Its Application to Engineer a Vitamin B12 Whole‐Cell Ribosensor

open access: yesMicrobial Biotechnology, Volume 18, Issue 6, June 2025.
Molecular and functional experiments highlight the relevance of species‐specific polymorphisms in a B12 riboswitch of the Mycobacterium genus. This information provided proof‐of‐concept to engineer a whole‐cell biosensor capable of detecting vitamin B12. ABSTRACT Vitamin B12 metabolism differs among members of the Mycobacterium genus.
Elena Campos‐Pardos   +6 more
wiley   +1 more source

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