Results 1 to 10 of about 402,861 (290)
Generalized Cortical Dysplasia
Pediatric Neurology Briefs, 1991 The clinical and neuropathological findings in three children with diffuse cortical dysplasia are reported from the Departments of Pathology, Neurology and Pediatrics, University of Rochester Medical Center, Rochester, NY.
J Gordon Millichap
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Differentially expressed proteins underlying childhood cortical dysplasia with epilepsy identified by iTRAQ proteomic profiling. [PDF]
PLoS ONE, 2017 Cortical dysplasia accounts for at least 14% of epilepsy cases, and is mostly seen in children. However, the understanding of molecular mechanisms and pathogenesis underlying cortical dysplasia is limited.
Lu Qin +7 more
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MRI of focal cortical dysplasia [PDF]
Neuroradiology, 2021 Abstract Focal cortical dysplasia (FCD) are histopathologically categorized in ILAE type I to III. Mild malformations of cortical development (mMCD) including those with oligodendroglial hyperplasia (MOGHE) are to be integrated into this classification yet.
Horst Urbach +4 more
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Signal Transduction and Targeted Therapy, 2023 Seizures due to cortical dysplasia are notorious for their poor prognosis even with medications and surgery, likely due to the widespread seizure network. Previous studies have primarily focused on the disruption of dysplastic lesions, rather than remote
Yang Zheng +18 more
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Focal Cortical Dysplasia [PDF]
Seminars in Neurology, 2015 Focal cortical dysplasias are common malformations of cerebral cortical development and are highly associated with medically intractable epilepsy. They have been classified into neuropathological subtypes (type Ia, Ib, IIa, IIb, and III) based on the severity of cytoarchitectural disruption--tangential or radial dispersion, or loss of laminar structure-
Peter B Crino
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Focal cortical dysplasia: Updates
Indian Journal of Pathology and Microbiology, 2022 Focal cortical dysplasias (FCDs) represent the third most frequent cause of drug-resistant focal epilepsy in adults (after hippocampal sclerosis and tumours) submitted to surgery, and the most common in the pediatric age group.
Jorge Pinheiro, Mrinalini Honavar
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Brain Sciences, 2023 Objectives: The purpose of this research was to investigate whether MRI and Simultaneous Hybrid PET/MRI images were consistent in the histological classification of patients with focal cortical dysplasia. Additionally, this research aimed to evaluate the
Ning Wang +11 more
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Malformation of the Cortical Development Associated with Severe Clusters of Epileptic Seizures
Veterinary Sciences, 2022 Three cases of the malformation of the cortical development are described: a mixed breed dog and a Border Collie pup with a focal and diffuse cortical dysplasia, respectively, and a kitten with lissencephaly. All cases presented with intractable epilepsy
Aurora Cocchetto +3 more
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An integrated genetic analysis of epileptogenic brain malformed lesions
Acta Neuropathologica Communications, 2023 Focal cortical dysplasia is the most common malformation during cortical development, sometimes excised by epilepsy surgery and often caused by somatic variants of the mTOR pathway genes.
Atsushi Fujita +33 more
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Limbic network co‐localization predicts pharmacoresistance in dysplasia‐related epilepsy
Annals of Clinical and Translational Neurology, 2023 To evaluate the role of focal cortical dysplasia co‐localization to cortical functional networks in the development of pharmacoresistance. One hundred thirty‐six focal cortical dysplasia patients with 3.0 T or 1.5 T MRI were identified from clinical ...
Nathan T. Cohen +7 more
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