Multimodal age-dependent diffusion-MRI analysis of the neocortex in a rat model of cortical dysplasia [PDF]
Scientific ReportsThe neocortex is a highly organized structure, with region-specific spatial patterns of cells and fibers constituting cyto- and myelo-architecture, respectively.
Paulina J. Villaseñor +4 more
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Glial regenerative cell types in the superficial cortex in cortical dysplasia subtypes [PDF]
, 2021 Purpose: Focal Cortical Dysplasias (FCD) are localized malformative brain lesions in epilepsy. FCD3a associated with hippocampal sclerosis, affects the superficial cortex and is presumed to have an ‘acquired’ rather than developmental origin.
van der Pijl, R. +3 more
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A quantitative study of white matter hypomyelination and oligodendroglial maturation in focal cortical dysplasia type II. [PDF]
, 2013 A diagnostic feature of focal cortical dysplasia (FCD) type II on magnetic resonance imaging (MRI) is increased subcortical white matter (WM) signal on T2 sequences corresponding to hypomyelination, the cause of which is unknown.
Martinian, L +14 more
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Cortical Dysplasia in children [PDF]
Child's Nervous System, 2014 Taylor and colleagues in 1971 published a seminal paper entitled Focal Dysplasia of the Cerebral Cortex in Epilepsy [1]. In this paper, they discussed in detail 10 cases of patients with epilepsy operated on byMurray Falconer (8 cases) in the Guy’s—Maudsley—King’s Neurosurgical Unit and 2 other cases treated at other Institutions.
Helio Rubens, Machado +1 more
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The changing landscape in epilepsy imaging: Unmasking subtle and unique entities
Diagnostic and Interventional Radiology, 2022 Dramatic changes have occurred recently in the field of epilepsy, including a fundamental shift in the etiology of epileptogenic substrates found at surgery. Hippocampal sclerosis is no longer the most common etiology found at epilepsy surgery and this
Mehmet E. Adin +5 more
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mTOR pathway: Insights into an established pathway for brain mosaicism in epilepsy
Neurobiology of Disease, 2023 The mechanistic target of rapamycin (mTOR) signaling pathway is an essential regulator of numerous cellular activities such as metabolism, growth, proliferation, and survival.
Anna Gerasimenko +2 more
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Journal of Orthopaedic Reports, 2022 Introduction: Fibrous dysplasia is a non-inheritable congenital disorder characterized by bone-forming expansile fibrous lesions that disrupt normal bone architecture.
Mitali Mokashi +3 more
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Focal cortical dysplasia with prolonged ictal asystole, a case report
Clinical Neurophysiology Practice, 2021 Introduction: Cortical dysplasia carries significant morbidities such as seizures and delayed milestones. Focal cortical dysplasia (FCD) causes refractory epilepsy with various seizure types depending on the location and extent of the dysplasia.
Ahmad wali, Fowzia Siddiqui
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A Case of a Solitary Cortical Tuber with No Other Manifestations of Tuberous Sclerosis Complex Mimicking Focal Cortical Dysplasia Type II with Calcification [PDF]
, 2022 Cortical tubers are one of the typical intracranial manifestations of tuberous sclerosis complex (TSC). Multiple cortical tubers are easy to diagnose as TSC; however, a solitary cortical tuber without any other cutaneous or visceral organ manifestations ...
Kawai, Koji +10 more
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Neuroimaging of septo-optic dysplasia-plus with midbrain hypoplasia and ophthalmoplegia
eNeurologicalSci, 2020 Septo-optic dysplasia is a rare brain malformation that can be associated with anomalous cortical development, such as schizencephaly, which is referred to as septo-optic dysplasia plus.
Colin Y. Wang, Daniel T. Ginat
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