Results 241 to 250 of about 402,861 (290)
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Epilepsy and cortical dysplasias
Current Treatment Options in Neurology, 2000Focal cortical dysplasias (FCD) and diffuse cortical dysplasias (DCD) are a heterogeneous group of disorders defined by abnormal cerebral cortical cytoarchitecture that are associated with epilepsy. Patients with either DCD or FCD may suffer from a variety of epilepsy subtypes and these are often refractory to most anti-epileptic drugs (AEDs) despite ...
, Crino, , Chou
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MRI of focal cortical dysplasia
Neuroradiology, 1998We studied nine cases of focal cortical dysplasia (FCD) by MRI, with surface-rendered 3D reconstructions. One case was also examined using single-voxel proton MR spectroscopy (MRS). The histological features were reviewed and correlated with the MRI findings.
B C, Lee +4 more
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Archives of Neurology, 2003
Focal cortical dysplasia (FCD) is a type of malformation of cortical development that primarily affects areas of neocortex. It can be identified on conventional magnetic resonance imaging as focal cortical thickening, abnormal gyration, and blurring between gray and white matter, often associated with clusters of heterotopic neurons.
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Focal cortical dysplasia (FCD) is a type of malformation of cortical development that primarily affects areas of neocortex. It can be identified on conventional magnetic resonance imaging as focal cortical thickening, abnormal gyration, and blurring between gray and white matter, often associated with clusters of heterotopic neurons.
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Terminology and classification of the cortical dysplasias
Neurology, 2004There have been difficulties in achieving a uniform terminology in the literature regarding issues of classification with respect to focal cortical dysplasias (FCDs) associated with epilepsy.S: To review and refine the current terminology and classification issues of potential clinical relevance to epileptologists, neuroradiologists, and ...
Palmini A +10 more
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Surgery for focal cortical dysplasia
Neurosurgery Clinics of North America, 2002Interest in surgery for focal cortical dysplasia has grown with the enhanced ability to detect these lesions preoperatively with modern imaging techniques. This article focuses on the surgical management of epilepsy associated with focal cortical dysplasia. The authors highlight the approaches practiced at Yale University, review their recent series of
Katrina S, Firlik, Dennis D, Spencer
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Dementia associated with cortical dysplasia
Acta Neuropathologica, 1998Detailed neuropathologic examination was performed on a 47.5-year-old man with an unusual adult-onset dementing illness. His initial symptoms were those of depression, memory loss, and personality change. He developed progressive cognitive decline with prominent psychiatric symptoms. Seizures began approximately 11 months prior to death and he died 5.5
E H, Bigio +6 more
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Focal Cortical Dysplasia in Children
Developmental Neuroscience, 1999Cortical dysplasia (CD) is now recognized as one of the major causes of pediatric focal neocortical epilepsy, and surgical procedures have been considered early in life. However, the mechanisms involved in seizure generation and intractability in these patients are still unknown.
A, Hilbig +5 more
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Pathologic characteristics of the cortical dysplasias
Neurosurgery Clinics of North America, 2002The gross and microscopic features of cortical dysplasia (malformations caused by abnormalities of cortical development) are reviewed and illustrated in this article. The pathologic associations of neurocutaneous disorders, neoplasms, and hippocampal sclerosis with cortical dysplasia also are discussed.
Richard A, Prayson +2 more
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Neurology, 1998
Human cortical dysplastic lesions are frequently associated with severe partial epilepsies. We report an immunocytochemical investigation on cortical tissue from three surgically treated patients, 20, 38, and 14 years old, with intractable epilepsy due to cortical dysplasia. The studies were performed using antibodies recognizing cytoskeletal proteins,
R, Spreafico +10 more
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Human cortical dysplastic lesions are frequently associated with severe partial epilepsies. We report an immunocytochemical investigation on cortical tissue from three surgically treated patients, 20, 38, and 14 years old, with intractable epilepsy due to cortical dysplasia. The studies were performed using antibodies recognizing cytoskeletal proteins,
R, Spreafico +10 more
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Nestin expression in cortical dysplasia
Journal of Neurosurgery, 2001Object. It is recognized that cortical dysplasia (CD) is associated with an increased incidence of glioneuronal neoplasms. Among hypothetical considerations, there is the possibility that CD and other neuronal migration abnormalities harbor dysmature cells with the potential to give rise to glioneuronal neoplasms.
N, Duggal, S, Iskander, R R, Hammond
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