Results 251 to 260 of about 402,861 (290)

Cortical dysplasias

1997
Abstract Classification based on Dobyns and Truwit (1995). Lissencephaly (agyria/pachygyria diffuse with abnormally thick cortex and only four layers). Also called lissencephaly type 1: classical: Miller-Dieker syndrome; Lissencephaly sequence; lissencephaly with very small head including a small cerebellum; Cobblestone lissencephaly or ...
openaire   +1 more source

Mechanisms of epileptogenicity in cortical dysplasias

Neurology, 2004
Cortical dysplasias (CDs) increasingly are recognized as pathologic substrates in patients with medically intractable epilepsy. Several studies have demonstrated the intrinsic epileptogenicity of these lesions, but the cellular and molecular mechanisms responsible for seizure initiation remain unknown.
I, Najm, Z, Ying, T, Babb, P B, Crino, R, Macdonald, G W, Mathern, R, Spreafico   +6 more
openaire   +2 more sources

Focal cortical dysplasia in meningioangiomatosis

Clinical Neuropathology, 2015
Meningioangiomatosis is a rare, benign, developmental, or hamartomatous lesion which may involve the leptomeninges and underlying brain parenchyma. Histologically, meningioangiomatosis is marked by a proliferation of blood vessels in the parenchyma, rimmed by collars of spindled meningothelial cells.
Matthew M, Grabowski, Richard A, Prayson
openaire   +2 more sources

Cortical Dysplasia: Zones of Epileptogenesis

American Journal of Electroneurodiagnostic Technology, 2005
Cortical dysplasia describes a wide range of cerebral cortex structural anomalies and is a condition attributed to multiple etiologies including disruption in the migration of the maturing neurons, disturbance of the process of programmed cell death in the fetal brain, and even noxious environmental influence. Cortical dysplasia can be focal or diffuse
Lucy R, Sullivan, Lynda L, Kull, Daniel B, Sweeney, Cinque P, Davis   +3 more
openaire   +2 more sources

Neuroimaging of Focal Cortical Dysplasia

Journal of Neuroimaging, 2006
ABSTRACT Focal cortical dysplasia (FCD) is a common cause of pharmacoresistant epilepsy that is amenable to surgical resective treatment. The identification of structural FCD by magnetic resonance imaging (MRI) can contribute to the detection of the epileptogenic zone and improve the outcome of epilepsy surgery.
Peter, Widdess-Walsh, Beate, Diehl, Imad, Najm   +2 more
openaire   +2 more sources

Familial Diffuse Cortical Dysplasia

Archives of Neurology, 1994
Two brothers are described with a syndrome characterized by mental retardation, atypical absence, atonic and generalized tonic-clonic seizures, and bilateral symmetrical slow spike and wave discharges on electroencephalograms. Magnetic resonance imaging revealed dysplastic cortex probably representing pachygyria primarily over the parietal regions ...
openaire   +2 more sources

Management of cortical dysplasia in epilepsy

2012
Focal cortical dysplasias (FCD) are increasingly diagnosed as a cause of symptomatic focal epilepsy in paediatric and adult patients. Nowadays, focal cortical dysplasias are identified as the underlying pathology in up to 25% of patients with focal epilepsies.
Fauser, Susanne, Zentner, Josef
openaire   +3 more sources

Cortical dysplasia: neuropathological aspects

Child's Nervous System, 2006
Malformations of the cerebral cortex are a frequent cause of pharmacoresistant epilepsies and developmental disorders.The incidence of cortical dysplasias in epilepsy surgical series varies from 12 to 40% and focal cortical dysplasias (FCD) are one of the most common neuropathological findings in resection specimens from pediatric patients undergoing ...
openaire   +2 more sources

Focal Cortical Dysplasia: An Update on Diagnosis and Treatment

Expert Review of Neurotherapeutics, 2021
Carmen Barba, Renzo Guerrini
exaly  

Focal cortical dysplasia

Neurology India, 2018
openaire   +2 more sources