Results 51 to 60 of about 1,585,655 (272)
Mapping the cortical representation of the lumbar paravertebral muscles [PDF]
, 2007 Objective: The aim of this study was to map the cortical representation of the lumbar spine paravertebral (LP) muscles in healthy subjects. Methods: Transcranial magnetic stimulation (TMS) was employed to map the cortical representations of the LP ...
Cossar, J +3 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Cortical neurodevelopment in pre-manifest Huntington's disease
NeuroImage: Clinical, 2019 Background: The expression of the HTT CAG repeat expansion mutation causes neurodegeneration in Huntington's disease (HD). Objectives: In light of the – mainly in-vitro – evidence suggesting an additional role of huntingtin in neurodevelopment we used 3T
Katharina M. Kubera +4 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Floral organ development is fundamental to sexual reproduction in angiosperms. Many key floral regulators (most of which are transcription factors) have been identified and shown to modulate floral meristem determinacy and floral organ identity, but not ...
Huifang Ma, Liyuan Xu, Ying Fu, Lei Zhu
doaj +1 more source
Reconciling predictive coding and biased competition models of cortical function [PDF]
, 2008 A simple variation of the standard biased competition model is shown, via some trivial mathematical manipulations, to be identical to predictive coding. Specifically, it is shown that a particular implementation of the biased competition model, in which ...
Spratling, Michael +3 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Figuring Time by Space: Representing sensory motion in cortical maps [PDF]
, 2011 How does the brain represent sensory input? When stimuli move across sensor surfaces, such as a light source moving across the retina, sound moving between the ears, or contact moving over the skin, patterns of activation propagate across sheets of ...
Wilson, Stuart
core +5 more sources
Resting state cortical EEG rhythms in Alzheimer's disease: toward EEG markers for clinical applications: a review [PDF]
, 2013 The human brain contains an intricate network of about 100 billion neurons. Aging of the brain is characterized by a combination of synaptic pruning, loss of cortico-cortical connections, and neuronal apoptosis that provoke an age-dependent decline of ...
Lizio, Roberta +24 more
core +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source