Results 91 to 100 of about 462,073 (262)

Role of mechanical factors in cortical folding development

Physical Review E, 2015
Deciphering mysteries of the structure-function relationship in cortical folding has emerged as the cynosure of recent research on brain. Understanding the mechanism of convolution patterns can provide useful insight into the normal and pathological brain function.
Mir Jalil, Razavi, Tuo, Zhang, Xiao, Li, Tianming, Liu, Xianqiao, Wang   +4 more
openaire   +3 more sources

Serostatus‐Specific Prognostic Profiles and Phenotype‐Dependent Therapeutic Windows in Autoimmune Encephalitis: A Multicenter Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background While autoimmune encephalitis (AE) outcomes vary, serostatus‐specific prognostic determinants and institutional clustering effects remain poorly characterized. We aimed to delineate the distinct prognostic architecture of AE, identifying serostatus‐specific risk factors and potential therapeutic windows.
Xiaohong Tang, Jingxian Wang, Kaixin Zhu, Zhen Zhang, Liao Wu, Wei Wang, Chang Li, Qingyun Li, Hao Li, Jinghua Chen, Zhangxu Lian, Bin Liu, Tengfei Liu, Chunmei Wen, Nuan Wang, Sen Qun, Lishun Xiao, Qingwei Lai   +17 more
wiley   +1 more source

Discovering cortical sulcal folding patterns in neonates using large‐scale dataset [PDF]

, 2018
The folding of the human cerebral cortex is highly complex and variable across individuals, but certain common major patterns of cortical folding do exist.
Weili Lin, Wang, Li, Li Wang, Lin, Weili, Meng, Yu, Li, Gang, Gang Li, John H Gilmore, Shen, Dinggang, Yu Meng, Dinggang Shen, Gilmore, John H   +11 more
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Physical biology of human brain development

Frontiers in Cellular Neuroscience, 2015
Neurodevelopment is a complex, dynamic process that involves a precisely orchestrated sequence of genetic, environmental, biochemical, and physical events.
Silvia eBudday, Paul eSteinmann, Ellen eKuhl   +2 more
doaj   +1 more source

Additively Manufactured Geometry‐Reconfigurable Soft Neural Probes With Monolithic Multifunctionality

Advanced Functional Materials, EarlyView.
A geometry‐reconfigured additive manufacturing strategy converts planar printed soft materials into soft compact neural probes with integrated hydrogel electrodes and microfluidic channels. The resulting NeuroMAP platform enables scalable multichannel recording, localized chemical delivery, stable in vivo electrophysiological recording, and reduced ...
Hyunjin Lee, Xinyi Wang, Sirui Li, Jihyang Park, Hyunseok Lee, Jianting Yao, Kedar Narayan, Yuqi Wang, Jiashu Ren, Yueqi Deng, Salahuddin Ahmed, Denver I. Greenawalt, Archana Pandiyan, Loganathan Veeramuthu, Chi‐Ching Kuo, Tao Zhou   +15 more
wiley   +1 more source

Stress landscape of folding brain serves as a map for axonal pathfinding

Nature Communications
Understanding the mechanics linking cortical folding and brain connectivity is crucial for both healthy and abnormal brain development. Despite the importance of this relationship, existing models fail to explain how growing axon bundles navigate the ...
Akbar Solhtalab, Ali H. Foroughi, Lana Pierotich, Mir Jalil Razavi   +3 more
doaj   +1 more source

Parametric Representation of Cortical Surface Folding Based on Polynomials [PDF]

, 2009
The development of folding descriptors as an effective approach for describing geometrical complexity and variation of the human cerebral cortex has been of great interests. This paper presents a parametric representation of cortical surface patches using polynomials, that is, the primitive cortical patch is compactly and effectively described by four ...
Tuo Zhang, Lei Guo 0002, Gang Li 0001, Jingxin Nie, Tianming Liu 0001   +4 more
openaire   +3 more sources

Programming Neuromorphic Plasticity Through Ionic and Electronic Coupling in Organic Electrochemical Transistors

Advanced Functional Materials, EarlyView.
Neuromorphic plasticity in OECTs is governed by the post‐stimulus evolution of coupled ionic and electronic states. Semiconductor chemistry and morphology, electrolyte composition and interfaces, and device architecture regulate ion injection, transport, confinement, and release, shifting responses from rapidly relaxing STP to metastable memory and ...
Inho Lee, Hyoik Jang, Ji Hwan Kim, Jonghyun Won, Namhee Kim, Wonseok Shin, Giwon Lee, Eunho Lee, Daegun Kim, Sungjun Park   +9 more
wiley   +1 more source

Early cortical surface plasticity relates to basic mathematical learning

NeuroImage, 2020
Children lay the foundation for later academic achievement by acquiring core mathematical abilities in the first school years. Neural reorganization processes associated with individual differences in early mathematical learning, however, are still ...
Ulrike Kuhl, Angela D. Friederici, Michael A. Skeide, Angela D. Friederici, Frank Emmrich, Jens Brauer, Arndt Wilcke, Nicole Neef, Johannes Boltze, Michael Skeide, Holger Kirsten, Gesa Schaadt, Bent Müller, Indra Kraft, Ivonne Czepezauer, Liane Dörr   +15 more
doaj   +1 more source