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Cortical malformations and epilepsy
Mental Retardation and Developmental Disabilities Research Reviews, 2000Brain malformations, resulting from aberrant patterns of brain development, are highly correlated with childhood seizure syndromes, as well as with cognitive disabilities and other neurological disorders. The structural malformations, often referred to as cortical dysplasia, are extremely varied, reflecting diverse underlying processes and critical ...
P A, Schwartzkroin, C A, Walsh
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Malformations of cortical development
Neuroimaging Clinics of North America, 2004Malformations of cortical development are an important cause of developmental delay and epilepsy. Proper identification of these malformations can greatly help in accurately counseling affected families and, in some cases, in the treatment of the epilepsy. Modem neuroimaging is an important tool in the diagnosis of these malformations.
Anthony James, Barkovich +1 more
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Malformations of Cortical Development
Neuroimaging Clinics of North AmericaMalformations of cortical development are complex and diverse. They are an etiology for drug-resistant epilepsy, and their imaging presentation may be striking or quite subtle. There are multiple schemes to classify this pathology group. One of the most well known is to group disorders based on the type of embryologic error that leads to each ...
Theodore, Betting, Theodore, Passe
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Cortical reorganization in malformations of cortical development
Neurology, 2004The evaluation for epilepsy surgery of patients with malformations of cortical development (MCDs) in areas of clinically important cerebral function is a challenge because of the unpredictable localization of critical sensory, motor, and cognitive function. Magnetoencephalography (MEG) source localization of evoked fields can address whether functional
Jorge G, Burneo +3 more
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Genetic malformations of cortical development
Experimental Brain Research, 2006The malformations of the cerebral cortex represent a major cause of developmental disabilities, severe epilepsy and reproductive disadvantage. The advent of high-resolution MRI techniques has facilitated the in vivo identification of a large group of cortical malformation phenotypes.
GUERRINI, RENZO, C. Marini
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Hemispheric malformations of cortical development
Neurology, 2004The term hemispheric malformations of cortical development (MCDs) is used in this article to represent congenital malformations that predominantly or exclusively involve complete or substantial portion of one cerebral hemisphere. Hemispheric MCDs usually present during early childhood with intractable epilepsy, cognitive delay, and contralateral ...
Ajay, Gupta +3 more
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Focal malformations of cortical development
Neurology, 2004Malformations of cortical development (MCDs) represent a heterogeneous group of disorders characterized by abnormal cortical and glial proliferation, neuronal migration, and cortical organization. Advances in neuroimaging have allowed for the growing recognition of a variety of developmental lesions associated with focal seizures.
N, Foldvary-Schaefer +4 more
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Imaging of malformations of cortical development
Epileptic Disorders, 2009ABSTRACT Malformations of cortical development (MCD) include a broad range of disorders that result from disruption of the major steps of cortical development: cell proliferation in germinal zones, neuronal migration and cortical organization.
Nadia, Colombo +4 more
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Genetic Assessment of Cortical Malformations
Neuropediatrics, 2011Malformations of cortical development comprise a clinically and etiologically heterogeneous group of distinct structural abnormalities of the cerebral cortex, commonly identified during MR imaging of patients with seizure disorders and/or developmental delay.
U, Hehr, G, Schuierer
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Diffuse malformations of cortical development
2013Malformations of cortical development (MCD) represent a major cause of developmental disabilities and severe epilepsy. Advances in imaging and genetics have improved the diagnosis and classification of these conditions. Up to now, eight genes have been involved in different types of MCD.
Nadia, Bahi-Buisson, Renzo, Guerrini
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