Results 21 to 30 of about 30,052 (310)

Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model. [PDF]

J Clin Invest, 2021
Auffenberg E, Hedrich UB, Barbieri R, Miely D, Groschup B, Wuttke TV, Vogel N, Lührs P, Zanardi I, Bertelli S, Spielmann N, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Pusch M, Dichgans M, Lerche H, Gavazzo P, Plesnila N, Freilinger T.   +19 more
europepmc   +3 more sources

Cortical Spreading Depression and mitochondrial dysfunction with aging: Lessons from ethanol abuse [PDF]

Frontiers in Aging Neuroscience, 2014
Chronic consumption of ethanol has a damaging effect in various organs and metabolic functions, including liver, kidney, heart, pancreas, and brain (Sun and Sun, 2001; Bezerra Rde et al., 2005).
George E. eBarreto, Francisco eCapani, Ricardo eCabezas   +2 more
doaj   +4 more sources

Optogenetic cortical spreading depression originating from the primary visual cortex induces migraine-like pain and anxiety behaviors in freely moving C57BL/6 J mice. [PDF]

J Headache Pain
Yuan H, Na W, Li B, Miao S, Tang W, Kang L, Pi C, Yang C, Xie W, Wang T, Zhai D, Zhao D, Liu R, Yu S.   +13 more
europepmc   +3 more sources

Migrainous Infarction and Cortical Spreading Depression. [PDF]

Discoveries (Craiova), 2020
Migraine is a very common disorder of the nervous system. It shares similar physiological processes with stroke. Migrainous infarction is a rare complication of migraine with aura. The neuro-logical symptoms of migraine aura correspond to the cortical spreading depression and this depression can lead to a migrainous infarction. It is pertinent to state
Iftikhar W, Cheema FF, Khanal S, Khan QU.   +3 more
europepmc   +3 more sources

Sarcoma Family Kinase-Dependent Pannexin-1 Activation after Cortical Spreading Depression is Mediated by NR2A-Containing Receptors. [PDF]

Int J Mol Sci, 2020
Bu F, Nie L, Quinn JP, Wang M.
europepmc   +3 more sources

Sex differences in photophobic behaviors following cortical spreading depression in rats. [PDF]

Cephalalgia
Kaur M, Ward NA, Karlage KL, Morgans CW, Aicher SA, Largent-Milnes TM.   +5 more
europepmc   +2 more sources

Advances on the correlation between epilepsy and cortical spreading depression

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Cortical spreading depression (CSD) is a pathological depolarization wave caused by the collective depolarization of neurons that propagates slowly along the cerebral cortex and can transiently inhibit brain electrical activity, which is related to a ...
ZHANG Xu, WANG Xiang⁃qing
doaj   +1 more source

Gabapentin Suppresses Cortical Spreading Depression Susceptibility [PDF]

Journal of Cerebral Blood Flow & Metabolism, 2010
Cortical spreading depression (CSD) is an intense depolarization wave implicated in the pathophysiology of brain injury states and migraine aura. As Cav2.1 channels modulate CSD susceptibility, we tested gabapentin, which inhibits Cav2.1 through high-affinity binding to its α2δ subunit, on CSD susceptibility in anesthetized rats. Gabapentin, 100 or 200
Hoffmann, Ulrike, Dilekoz, ERGİN, Ayata, Cenk, Kudo, Chiho   +3 more
openaire   +3 more sources

Immunomodulatory Effect of Toll-Like Receptor-3 Ligand Poly I:C on Cortical Spreading Depression [PDF]

, 2009
The release of inflammatory mediators following cortical spreading depression (CSD) is suggested to play a role in pathophysiology of CSD-related neurological disorders.
Aghabarari, A., Ghaemi, A., Gorji, A., Khaleghi Ghadiri, M., Khodaie, B., Lotfinia, A.A., Lotfinia, M., Meuth, S., Sajadian, A.   +8 more
core   +3 more sources

Cortical spreading depression-induced preconditioning in the brain

Neural Regeneration Research, 2016
Cortical spreading depression is a technique used to depolarize neurons. During focal or global ischemia, cortical spreading depression-induced preconditioning can enhance tolerance of further injury. However, the underlying mechanism for this phenomenon
Ping-ping Shen, Shuai Hou, Di Ma, Ming-ming Zhao, Ming-qin Zhu, Jing-dian Zhang, Liang-shu Feng, Li Cui, Jia-chun Feng   +8 more
doaj   +1 more source