Genetic variation in CRHR1 is associated with short-term respiratory response to corticosteroids in preterm infants at risk for bronchopulmonary dysplasia. [PDF]
BackgroundBronchopulmonary dysplasia (BPD) is an orphan disease and advances in prevention and treatment are lacking. The clinical efficacy of systemic corticosteroid therapy to reduce the severity of lung disease and BPD is highly variable.
Ballard, Philip L +5 more
core +1 more source
Epidural corticosteroid injections for lumbosacral radicular pain.
BACKGROUND Lumbosacral radicular pain (commonly called sciatica) is a syndrome involving patients who report radiating leg pain. Epidural corticosteroid injections deliver a corticosteroid dose into the epidural space, with the aim of reducing the local ...
Crystian B. Oliveira +9 more
semanticscholar +1 more source
Nilotinib-Induced Immune-Mediated Liver Injury: Corticosteroid as a Possible Therapeutic Option
Introduction: Nilotinib is a BCR-ABL tyrosine kinase inhibitor approved for chronic myeloid leukemia. We present a case of severe immune-mediated liver injury by nilotinib treatment.Case report: A 59-year-old woman was referred to the liver clinic ...
Hyun Yang +7 more
doaj +1 more source
Effects of Dexamethasone and Pentoxifylline on Mania-like and Depression-like Behaviors in Rats
Several studies support the notion that inflammation plays a role in the pathophysiology and treatment approaches of psychiatric illnesses, particularly mood disorders.
Ahmad Nassar, Abed N. Azab
doaj +1 more source
Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokines—an exploratory study [PDF]
<p>Background: Current cigarette smoking is associated with reduced acute responses to corticosteroids and worse clinical outcomes in stable chronic asthma. The mechanism by which current smoking promotes this altered behavior is currently unclear.
A McKay +40 more
core +4 more sources
Choroidal changes in eyes treated with high-dose systemic corticosteroids for optic neuritis [PDF]
AIM: To analyze the effect of systemic high-dose corticosteroid on the choroid in patients with unilateral optic neuritis. METHODS: A retrospective comparative cohort study.
Jun Hyuk Lee +4 more
doaj +1 more source
Symptomatic adrenal insufficiency during inhaled corticosteroid treatment [PDF]
Symptomatic adrenal insufficiency, presenting as hypoglycaemia or poor weight gain, may occur on withdrawal of corticosteroid treatment but has not previously been reported during inhaled corticosteroid treatment.
Clayton, P.E. +5 more
core +1 more source
Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events [PDF]
Background An increase in serious adverse events with both regular formoterol and regular salmeterol in chronic asthma has been demonstrated in comparison with placebo in previous Cochrane reviews.
Aalbers +27 more
core +2 more sources
Corticosteroid treatment in severe COVID-19 patients with acute respiratory distress syndrome.
BACKGROUNDCorticosteroids are widely used in patients with COVID 19, although their benefit-to-risk ratio remains controversial.METHODSPatients with severe COVID-19-related acute respiratory distress syndrome (ARDS) were included from December 29, 2019 ...
Jiao Liu +19 more
semanticscholar +1 more source
Interferon beta in multiple sclerosis: experience in a British specialist multiple sclerosis centre [PDF]
Background: The efficacy of interferon beta (IFN beta) is well established in relapsing-remitting multiple sclerosis (MS). However, the use of this drug in clinical practice is complex, especially because it is only partially effective, its long term ...
Dubois, B.D. +7 more
core +2 more sources

