BackgroundOral lichen planus (OLP) is a relatively common chronic T cell-mediated disease characterized by pain and inflammation. Clobetasol propionate (CLO) is the first-line drug in the treatment of OLP. The meta-analysis aimed to evaluate the efficacy
Tao Zheng+6 more
doaj +1 more source
Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group. [PDF]
Cancer immunotherapy has transformed the treatment of cancer. However, increasing use of immune-based therapies, including the widely used class of agents known as immune checkpoint inhibitors, has exposed a discrete group of immune-related adverse ...
Abdallah, K.+80 more
core +2 more sources
Diabetic Retinopathy: New Treatment Approaches Targeting Redox and Immune Mechanisms
Diabetic retinopathy (DR) represents a severe complication of diabetes mellitus, characterized by irreversible visual impairment resulting from microvascular abnormalities.
Qi Tang+6 more
doaj +1 more source
OBJETIVO: Avaliar crescimento e composição corporal em crianças e adolescentes com Síndrome Nefrótica Córtico-Dependente (SNCD). MATERIAL E MÉTODOS: Foram incluídos todos os pacientes de 5 a 18 anos, em acompanhamento por pelo menos dois anos, com ...
Iza de Castro Oliveira+1 more
doaj +1 more source
Reported adverse drug reactions during the use of inhaled steroids in children with asthma in the Netherlands [PDF]
Objective: Inhaled corticosteroids (ICS) are widely used in the treatment of asthma. We studied the suspected adverse drug reactions (sADRs) reported during the use of ICS in the Netherlands. Methods: In the Netherlands, health professionals and patients
de Jong-van den Berg, L.T.W.+4 more
core +1 more source
MODERN VIEW OF DIAGNOSIS AND TREATMENT OF MYASTHENIA GRAVIS. CASE REPORT
Introduction. Myasthenia gravis (MG) or Erb-Goldflam syndrome is an autoimmune neuromuscular disease based on autoaggression of humoral immunity against elements of neuromuscular synapses and intracellular structures of muscle fibers (antibodies to ...
Tatiana V. Chernii+2 more
doaj +1 more source
Reduced bone mineral density in men after heart transplantation
Heart transplantation is associated with rapid bone loss and an increased prevalence and incidence of fractures. The aim of the present study was to compare the bone mineral density (BMD) of 30 heart transplant (HT) recipients to that of 31 chronic heart
J.R. Anijar+4 more
doaj +1 more source
Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury. [PDF]
Klebsiella pneumoniae is a leading cause of gram-negative bacterial pneumonia, often resulting in bacteremia concurrent with the localized pulmonary infection.
Cogen, Anna L+4 more
core +1 more source
Safe use of Dexamethasone in pediatrics: design and evaluation of a novel stable oral suspension
Dexamethasone is used in pediatrics mainly for treatment of croup and bronchopulmonary dysplasia. Commercially available pediatric oral formulations include inadequate excipients for this population. When there are only commercially available oral dosage
Santoveña-Estévez Ana+5 more
doaj +1 more source
Topical clobetasol for the treatment of toxic epidermal necrolysis: study protocol for a randomized controlled trial. [PDF]
BackgroundToxic epidermal necrolysis (TEN) is a rare systemic allergic drug eruption with high patient mortality. Currently, no established treatments have been shown to be effective for TEN beyond supportive care.
Kim, Kyoungmi+6 more
core +4 more sources