Results 191 to 200 of about 515,448 (335)

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel   +12 more
wiley   +1 more source

Association of systemic corticosteroids and clinical outcomes in children hospitalised with severe orbital infections. [PDF]

open access: yesBMJ Paediatr Open
Gonsalves CL   +19 more
europepmc   +1 more source

Nano‐networks via reaction‐induced self‐assembly coordinate spatiotemporal multi‐drug delivery for acute kidney injury therapy

open access: yesBMEMat, EarlyView.
Multifunctional nano‐networks (NNWs) are prepared via reaction‐induced self‐assembly (RISA) of spermidine (SPD), epigallocatechin gallate (EGCG), 2‐formylphenylboronic acid (2‐FPBA), and deferoxamine (DFO) through dynamic iminoboronate bonds. These NNWs leverage the oxidative AKI microenvironment to trigger disintegration, enabling site‐specific ...
Juan Jin   +17 more
wiley   +1 more source

Pyoderma Gangrenosum with Biological Agents Therapy: A Systematic Review. [PDF]

open access: yesClin Cosmet Investig Dermatol
Tan B   +8 more
europepmc   +1 more source

A Novel Patient‐Specific Landmark‐Guided Approach for Intramuscular Botulinum Neurotoxin Injections Into the Rotator Cuff: A Cadaveric Study

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Myofascial pain syndrome (MFPS) causes chronic shoulder pain. Supraspinatus and infraspinatus, rotator cuff muscles innervated by the suprascapular nerve, are commonly affected. Intramuscular botulinum neurotoxin (BoNT) injections near motor points (i.e., visible nerve branch entry sites used as a proxy for motor endplates) are an effective ...
Dave Osinachukwu Duru   +5 more
wiley   +1 more source

Association of Pulse Dose Corticosteroids With Outcomes Among Patients With Acute Exacerbations of Idiopathic Pulmonary Fibrosis. [PDF]

open access: yesCHEST Pulm
Shankar DA   +9 more
europepmc   +1 more source

The TRIP database showed most Acute Respiratory Infections questions were already addressed by Cochrane reviews [PDF]

open access: yes, 2019
Brassey, Jon   +4 more
core   +1 more source

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