Results 11 to 20 of about 39,594 (255)

Evolutionary engineering of Corynebacterium glutamicum [PDF]

open access: yesBiotechnology Journal, 2019
A unique feature of biotechnology is that we can harness the power of evolution to improve process performance. Rational engineering of microbial strains has led to the establishment of a variety of successful bioprocesses, but it is hampered by the ...
R. Stella   +3 more
semanticscholar   +4 more sources

Biosystem design of Corynebacterium glutamicum for bioproduction.

open access: yesCurrent Opinion in Biotechnology, 2022
Corynebacterium glutamicum, a natural glutamate-producing bacterium adopted for industrial production of amino acids, has been extensively explored recently for high-level biosynthesis of amino acid derivatives, bulk chemicals such as organic acids and short-chain alcohols, aromatics, and natural products, including polyphenols and terpenoids. Here, we
J. Zha   +6 more
semanticscholar   +4 more sources

Optimizing recombineering in Corynebacterium glutamicum [PDF]

open access: yesBiotechnology and Bioengineering, 2021
AbstractOwing to the increasing demand for amino acids and valuable commodities that can be produced by Corynebacterium glutamicum, there is a pressing need for new rapid genome engineering tools that improve the speed and efficiency of genomic insertions, deletions, and mutations.
Cheng Li   +3 more
openaire   +4 more sources

Production of indole by Corynebacterium glutamicum microbial cell factories for flavor and fragrance applications

open access: yesMicrobial Cell Factories, 2022
Background The nitrogen containing aromatic compound indole is known for its floral odor typical of jasmine blossoms. Due to its characteristic scent, it is frequently used in dairy products, tea drinks and fine fragrances.
Melanie Mindt   +8 more
semanticscholar   +1 more source

Engineered Corynebacterium glutamicum as the Platform for the Production of Aromatic Aldehydes

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Aromatic aldehydes, including 4-hydroxybenzaldehyde (4-HB aldehyde), protocatechuic (PC) aldehyde, and vanillin, are used as important flavors, fragrances, and pharmaceutical precursors and have several biological and therapeutic effects.
Hyun-Song Kim   +6 more
semanticscholar   +1 more source

Synthetic biology tools for engineering Corynebacterium glutamicum

open access: yesComputational and Structural Biotechnology Journal, 2023
Corynebacterium glutamicum is a promising organism for the industrial production of amino acids, fuels, and various value-added chemicals. From the whole genome sequence release, C. glutamicum has been valuable in the field of industrial microbiology and
Gi Yeon Kim   +5 more
doaj   +1 more source

Functional food additives/ingredients production by engineered Corynebacterium glutamicum

open access: yesSystems Microbiology and Biomanufacturing, 2022
Corynebacterium glutamicum is a microbial production host established in the industry 60 years ago. It is mainly used for production of feed and food amino acids. As C.
Katarina Cankar   +2 more
semanticscholar   +1 more source

CRISPR-assisted rational flux-tuning and arrayed CRISPRi screening of an l-proline exporter for l-proline hyperproduction

open access: yesNature Communications, 2022
Corynebacterium glutamicum is a major workhorse in industrial biomanufacturing of amino acids. Here, the authors employ CRISPR-assisted rational flux-tuning and CRISPRi screening of a L-proline exporter to covert a wild-type C.
Jiao Liu   +15 more
doaj   +1 more source

Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being

open access: yesEssays in Biochemistry, 2021
The soil microbe Corynebacterium glutamicum is a leading workhorse in industrial biotechnology and has become famous for its power to synthetise amino acids and a range of bulk chemicals at high titre and yield.
Sabrina Wolf   +8 more
semanticscholar   +1 more source

Physiological Response of Corynebacterium glutamicum to Indole [PDF]

open access: yesMicroorganisms, 2020
The aromatic heterocyclic compound indole is widely spread in nature. Due to its floral odor indole finds application in dairy, flavor, and fragrance products. Indole is an inter- and intracellular signaling molecule influencing cell division, sporulation, or virulence in some bacteria that synthesize it from tryptophan by tryptophanase ...
Walter, Tatjana   +8 more
openaire   +3 more sources

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