Results 11 to 20 of about 13,958 (160)

Advances and Perspectives for Genome Editing Tools of Corynebacterium glutamicum

Frontiers in Microbiology, 2021
Corynebacterium glutamicum has been considered a promising synthetic biological platform for biomanufacturing and bioremediation. However, there are still some challenges in genetic manipulation of C. glutamicum.
Qingzhuo Wang, Jiao Zhang, Jiao Zhang, Naief H. Al Makishah, Xiaoman Sun, Zhiqiang Wen, Zhiqiang Wen, Yu Jiang, Sheng Yang, Sheng Yang   +9 more
doaj   +1 more source

Application of Corynebacterium glutamicum engineering display system in three generations of biorefinery

Microbial Cell Factories, 2022
The fermentation production of platform chemicals in biorefineries is a sustainable alternative to the current petroleum refining process. The natural advantages of Corynebacterium glutamicum in carbon metabolism have led to C. glutamicum being used as a
Kerui Lin, Shuangyan Han, Suiping Zheng
doaj   +1 more source

Blue-white colony screening on acetate and glucose in Corynebacterim glutamicum

浙江大学学报. 农业与生命科学版, 2002
To develop the blue-white colony screening with promoter test vector in Corynebacterium glutamicum, two vectors pROH7 and pROHO were constructed and transformed into Corynebacterium glutamicum ATCC 14752.
RUAN Hong, Robert Gerstmeir, Bernhard Eikmanns   +2 more
doaj   +1 more source

Advances in Synthetic Biology Techniques and Industrial Applications of Corynebacterium glutamicum

Fermentation, 2023
Corynebacterium glutamicum is a Gram-positive bacterium (non-spore-forming) that has been wildly used for amino acid production. Due to its stable protein secretion, low extracellular hydrolase activity, and non-toxicity, the application field of C ...
Yujue Wang, Qiang Wang, Aobo Sha, Kexin Ren, Mengkai Hu, Meijuan Xu, Xian Zhang, Zhiming Rao   +7 more
doaj   +1 more source

Genome-Wide Analysis of DtxR and HrrA Regulons Reveals Novel Targets and a High Level of Interconnectivity Between Iron and Heme Regulatory Networks in Corynebacterium glutamicum. [PDF]

Mol Microbiol
Krüger A, Weber U, Frunzke J.
europepmc   +2 more sources

AftD functions as an α1 → 5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core

The Cell Surface, 2018
Arabinogalactan (AG) is an essential structural macromolecule present in the cell wall of Mycobacterium tuberculosis, serving to connect peptidoglycan with the outer mycolic acid layer.
Luke J. Alderwick, Helen L. Birch, Karin Krumbach, Michael Bott, Lothar Eggeling, Gurdyal S. Besra   +5 more
doaj   +1 more source

Enhanced l-ornithine production from glucose and sucrose via manipulation of the fructose metabolic pathway in Corynebacterium glutamicum

Bioresources and Bioprocessing, 2022
l-Ornithine, an important non-essential amino acid, has considerable medicinal value in the treatment of complex liver diseases. Microbial fermentation strategies using robust engineered strains have remarkable potential for producing l-ornithine.
Libin Nie, Kexin Xu, Bin Zhong, Xiaoyu Wu, Zhongtao Ding, Xuelan Chen, Bin Zhang   +6 more
doaj   +1 more source

Novel Chromosome Organization Pattern in Actinomycetales—Overlapping Replication Cycles Combined with Diploidy

mBio, 2017
Bacteria regulate chromosome replication and segregation tightly with cell division to ensure faithful segregation of DNA to daughter generations. The underlying mechanisms have been addressed in several model species.
Kati Böhm, Fabian Meyer, Agata Rhomberg, Jörn Kalinowski, Catriona Donovan, Marc Bramkamp   +5 more
doaj   +1 more source

Characterization of OxyR as a negative transcriptional regulator that represses catalase production in Corynebacterium diphtheriae. [PDF]

PLoS ONE, 2012
Corynebacterium diphtheriae and Corynebacterium glutamicum each have one gene (cat) encoding catalase. In-frame Δcat mutants of C. diphtheriae and C. glutamicum were hyper-sensitive to growth inhibition and killing by H(2)O(2). In C.
Ju-Sim Kim, Randall K Holmes
doaj   +1 more source

Production of l-glutamate family amino acids in Corynebacterium glutamicum: Physiological mechanism, genetic modulation, and prospects

Synthetic and Systems Biotechnology, 2021
l-glutamate family amino acids (GFAAs), consisting of l-glutamate, l-arginine, l-citrulline, l-ornithine, l-proline, l-hydroxyproline, γ-aminobutyric acid, and 5-aminolevulinic acid, are widely applied in the food, pharmaceutical, cosmetic, and animal ...
Qi Sheng, Xiao-Yu Wu, Xinyi Xu, Xiaoming Tan, Zhimin Li, Bin Zhang   +5 more
doaj   +1 more source