Results 101 to 110 of about 205,622 (234)

Effect of PTGES3 on the Prognosis and Immune Regulation in Lung Adenocarcinoma

open access: yesAnalytical Cellular Pathology, 2023
Background. PTGES3 is upregulated in multiple cancer types and promotes tumorigenesis and progression. However, the clinical outcome and immune regulation of PTGES3 in lung adenocarcinoma (LUAD) are not fully understood.
Wenyan Jiang   +5 more
doaj   +1 more source

Cancer in Ancient Human Populations: Methods and Practice in Bioarchaeology and Paleopathology [PDF]

open access: yes, 2020
Best Undergraduate Writing in Anthropology Award, 2019-2020Despite its prevalence in contemporary public health, research on the paleopathology of cancer is still extremely limited.
Gardner, Elijah
core  

Clinical and molecular characterization of HER2 amplified-pancreatic cancer [PDF]

open access: yes, 2013
<p>Background: Pancreatic cancer is one of the most lethal and molecularly diverse malignancies. Repurposing of therapeutics that target specific molecular mechanisms in different disease types offers potential for rapid improvements in outcome ...
Biankin, A.V.   +27 more
core   +3 more sources

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri   +7 more
wiley   +1 more source

Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines

open access: yesGenome Medicine, 2017
Background Onco-proteogenomics aims to understand how changes in a cancer’s genome influences its proteome. One challenge in integrating these molecular data is the identification of aberrant protein products from mass-spectrometry (MS) datasets, as ...
Javier A. Alfaro   +5 more
doaj   +1 more source

Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients. [PDF]

open access: yesPLoS ONE, 2016
Circulating cell-free DNA (cfDNA) released from cancerous tissues has been found to harbor tumor-associated alterations and to represent the molecular composition of the tumor.
Steffen Dietz   +8 more
doaj   +1 more source

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas [PDF]

open access: yes, 2018
This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with ...
Abdel-Rahman, Mohamed H.   +784 more
core   +2 more sources

Jasmonates enhance plants tolerance grown in Cd‐contaminated environments: A comprehensive overview

open access: yesAnnals of Applied Biology, EarlyView.
Jasmonates (JAs) enhance plant tolerance to cadmium (Cd) stress by activating antioxidant defences but may reduce Cd uptake, limiting their effectiveness for phytoremediation. This review compiles studies that evaluated the effects of JA application on plants grown in Cd‐contaminated environments. Abstract Cadmium (Cd) is a toxic heavy metal and one of
Raja Yamma Rodrigues Souza   +2 more
wiley   +1 more source

Mathematics Is Biology's Next Microscope, Only Better; Biology Is Mathematics' Next Physics, Only Better [PDF]

open access: yes, 2004
Joel Cohen offers a historical and prospective analysis of the relationship between mathematics and ...
Anderson   +32 more
core   +3 more sources

PSMD12 Overexpression Promotes Lung Adenocarcinoma Progression via Ubiquitin–Proteasome Pathway Dysregulation

open access: yesCancer Science, EarlyView.
PSMD12, located on the frequently amplified 17q region in LUAD, is upregulated in tumors and associated with poor prognosis and advanced stage. Functional studies revealed that PSMD12 promotes cell proliferation and G2/M transition by inhibiting CDK1 ubiquitination and stabilizing CDK1.
Yuya Ono   +14 more
wiley   +1 more source

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