Results 91 to 100 of about 7,424,997 (207)

RNA-Based Next-Generation Sequencing Approach to Non-Small Cell Lung Cancer: A Single-Center Experience in Turkey

Human Heredity
Introduction: Lung cancer is a global health concern. Molecular analysis of tumor tissues, especially in non-small cell lung cancers, has become an integral part of a holistic approach to the management of the disease.
Orhan Gorukmez, Ozlem Gorukmez, Ali Topak   +2 more
doaj   +1 more source

Myelodysplasia‐Related Gene Mutation Burden Is Associated With Complete Remission After Induction Therapy in Acute Myeloid Leukemia, Not Otherwise Specified: Reclassification According to the Updated Classifications

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Updated classifications incorporating myelodysplasia‐related (MR) gene mutations reclassify many cases previously diagnosed as acute myeloid leukemia, not otherwise specified (AML, NOS). We evaluated the clinical significance of MR gene mutation burden, defined by mutation number and variant allele frequency (VAF), in AML, NOS ...
Taegeun Lee, Daehyun Chu, Miyoung Kim, Young‐Uk Cho, Sang‐Hyun Hwang, Je‐Hwan Lee, Yunsuk Choi, Eun‐Ji Choi, Ho Joon Im, Hyery Kim, Seongsoo Jang   +10 more
wiley   +1 more source

Cancer Trends: Breast cancer 1994-2016

, 2019
There were 62,052 cases of newly diagnosed invasive or in situ breast tumours registered in Ireland by the National Cancer Registry for the period 1994–2016, of which 56,366 were invasive (ICD10: C50) and 5,686 were carcinoma in situ (ICD10: D05 ...
National Cancer Registry Ireland (NCRI)
core  

HER3 Is an Actionable Target in Advanced Prostate Cancer.

, 2021
It has been recognized for decades that ERBB signaling is important in prostate cancer, but targeting ERBB receptors as a therapeutic strategy for prostate cancer has been ineffective clinically.
Bertan, C, Crespo, M, Guo, C, D'Ambrosio, M, Sharp, A, Rekowski, J, Swain, A, Carreira, S, Paschalis, A, Troiani, M, Ning, J, Gurel, B, de Bono, J, Sumanasuriya, S, PCF/SU2C International Prostate Cancer Dream Team,, Gil, V, Christova, R, Califano, A, Seed, G, Brina, D, Workman, P, Vasciaveo, A, Pereira, R, Dolling, D, Yuan, W, Flohr, P, Sheehan, B, Fowler, G, Rescigno, P, Neeb, A, Ferreira, A, Riisnaes, R, Alajati, A, Alimonti, A, Miranda, S, Buroni, L, Tunariu, N, Lambros, M, Aversa, C, Figueiredo, I, Shen, MM, Bianchini, D, Welti, J, Clarke, M, Boysen, G   +44 more
core   +1 more source

Cancer Trends: Soft Tissue Sarcomas [PDF]

, 2014
Sarcomas are a group of uncommon cancers that originate from mesenchymal cells as opposed to more well-known cancers that develop from epithelial tissue.
National Cancer Registry Ireland (NCRI)
core  

Big Data in Cancer Genomics: Computational Foundations and Emerging Pathways for Precision Oncology

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT This review aims to explore the computational foundations of big data in cancer genomics and examine emerging pathways that support precision oncology and personalized cancer care. A narrative review approach was adopted to synthesize evidence from PubMed, Scopus, Web of Science, and IEEE Xplore.
Nur Vanu, Nur Mohammad, Fahad Ahmed, Towsif Alam, Koushik Saha, Durga Shahi, Adib Hossain, Mia Md. Tofayel Gonee Manik, Mst. Rina Parvin   +8 more
wiley   +1 more source

HPV-associated cancers: cancer trends report [PDF]

Human papilloma virus (HPV) is a group of viruses known to infect the genital area, as well as the mouth and the throat. There are 13 HPV subtypes which are considered high-risk, as these are more likely to cause cell changes that over time can develop ...
National Cancer Registry Ireland (NCRI)
core  

Variant‐Specific Landscape of Mutual Exclusivity Among BRAF, EGFR, and KRAS Oncogenes Reveals Overlap With Functionally Antagonistic Mutant Pairs

International Journal of Cancer, Volume 159, Issue 7, Page 1715-1734, 1 October 2026.
Mutual exclusivity and co‐occurrence of oncogenic mutations reflect functional antagonism or dependence and may inform therapeutic strategies. However, most studies overlook variant‐level patterns. In this comprehensive, cross‐cohort analysis of BRAF, KRAS, and EGFR mutation subtypes, the most significant mutual exclusivity pairs overlapped with ...
Freya Vaeyens, Jan‐Patrick Hetzel, Khaldoon Abdullah, Carolien Eggermont, Catharina Olsen, Marco Mernberger, Ken Maes, Jelle Vlaeminck, Rainer Claus, Dries Vanisterbecq, Frederik Hes, Martin Pichler, Philippe Giron, Oleg Timofeev, Maxim Noeparast   +14 more
wiley   +1 more source

Cancer Trends: Mesothelioma

, 2012
Mesothelioma is a rare cancer of the thin lining that mainly covers the lungs and abdominal cavity. An average of 24 cases of mesothelioma was diagnosed per year in Ireland between 1994 and 2010 (Table 1), representing less than 0.2% of all invasive ...
National Cancer Registry Ireland (NCRI)
core  

Clinically Relevant Bleeding in Individuals With Cancer: Insights From a Nationwide Cohort Study

American Journal of Hematology, Volume 101, Issue 9, Page 2123-2136, September 2026.
ABSTRACT Cancer care is often complicated by coagulopathy leading to thrombosis and bleeding. While venous thromboembolism (VTE) has been extensively studied, bleeding remains an underestimated threat. To address this knowledge gap, we leveraged the Epic Cosmos database to determine the impact of cancer‐associated clinically relevant bleeding (CRB) in ...
Ming Y. Lim, Radhika Gangaraju, Omid Jafari, Zihan Yang, Joyce W. T. Tiong, Elizabeth C. L. Chiang, Shengling Ma, Jun Y. Jiang, Justine Ryu, Barbara D. Lam, Mrinal Ranjan, Ang Li   +11 more
wiley   +1 more source