Results 121 to 130 of about 16,100 (233)
Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture
Advanced Genetics, Volume 7, Issue 2, June 2026.This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley +1 more source
Abstract 388: A benchmark study for identifying cancer drivers in the non-coding part of the genome
, 2017 Purpose: Prioritizing potential deleterious variants is an essential task to guide research and validation of new pathological variants in the immensity of the genome.
Stefan Michiels +2 more
core +1 more source
HemaSphere, Volume 10, Issue 6, June 2026.Abstract IGLV3‐21R110 is a point mutation enabling autonomous B‐cell receptor (BCR) signaling in chronic lymphocytic leukemia (CLL). It has been associated with shorter time to first treatment and overall survival, but its effects have not been evaluated in phase 3 clinical trials or in patients treated with Bruton tyrosine kinase inhibitors.
Deyan Y. Yosifov +24 more
wiley +1 more source
Frontiers in OncologyBackground The role of long non-coding RNAs (lncRNAs) in the invasion and metastasis of gastric cancer remains largely unclear. Methods Integrating transcriptome data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases ...
Xue Jiang +5 more
semanticscholar +1 more source
HemaSphere, Volume 10, Issue 6, June 2026.Abstract In HIV‐ and tuberculosis (TB)‐endemic regions, lymphoma diagnosis is often delayed because symptoms can overlap with TB, and access to biopsy and specialized pathology is limited. To address this, we developed and internally evaluated the Access to Diagnosis using Liquid Biopsy (ADLiB) platform—a plasma cell‐free DNA (cfDNA)‐based approach ...
Katherine Antel +21 more
wiley +1 more source
PAX5 PXIs are frequently mutated in combination with PAX5 in human leukemia.
, 2019 (A) Pie charts showing the fraction of PAX5 PXIs (list of 239 entries) found mutated in the public cancer database COSMIC (cancer genes sensus V76) from the Sanger Institute Catalogue Of Somatic Mutations In Cancer web site, (http://cancer.sanger.ac.uk ...
Jacob Kuruvilla (7134935) +12 more
core +1 more source
Cancer incidence among 10,211 airline pilots: a Nordic study
, 2003 BACKGROUND: Commercial airline pilots are exposed to cosmic radiation and other potentially carcinogenic elements during work and leisure activities. HYPOTHESIS: Work-related factors affect cancer pattern of the pilots.
Aspholm, Rafael +12 more
core
HemaSphere, Volume 10, Issue 6, June 2026.Abstract Lenalidomide (Len) is the standard of care for red blood cell transfusion‐dependent (TD) patients with myelodysplastic syndromes (MDS) and del(5q). A Phase III clinical trial (SintraRev) demonstrated better efficacy of early treatment with Len in anemic del(5q) MDS patients prior to TD, but clonal evolution with this approach remained ...
Sofía Toribio Castelló +20 more
wiley +1 more source
HemaSphere, Volume 10, Issue 6, June 2026.Abstract Measurable residual disease assessment in bone marrow (BM‐MRD) is a crucial prognostic factor in multiple myeloma (MM), but its clinical use has some caveats, such as invasiveness, poor spatial representativity, and serial sampling. Novel minimally invasive approaches for monitoring peripheral residual disease (PRD) could facilitate its ...
Natalia Buenache +31 more
wiley +1 more source
ORCID: [Your ORCID ID] ABSTRACT Background: The genetic code comprises 22 amino acids (20 canonical plus Selenocysteine and Pyrrolysine). We hypothesized that arranging these amino acids in a circular wheel and classifying positions as "Prime" (positions 2, 3, 5, 7, 11, 13, 17, 19) or "Forbidden" (all others) would reveal non-random patterns in ...
openaire +1 more source