Results 111 to 120 of about 205,622 (234)
Cancer Science, EarlyView.Our findings indicate that a pediatric/AYA‐specific targeted panel deployed in a hospital can deliver rapid, clinically actionable molecular insights with high diagnostic and prognostic yield. This complements larger sequencing platforms by offering speed, focused content, and easier interpretation.
Masato Kojima +8 more
wiley +1 more source
Histopathology, EarlyView.Papillary renal cell carcinoma (pRCC) accounts for 15%–20% of RCC cases and is the second most common histologic subtype of RCC. In contrast to other common RCC subtypes, there continues to be ongoing debate about how to classify RCCs with papillary architecture and eosinophilic cytoplasm, given the heterogeneity of histologic, IHC and molecular ...
Melissa Yuwono Tjota +3 more
wiley +1 more source
The Competitive Mechanism Of Ezh1 And Ezh2 In Promoting Oscc
International Dental JournalAim or purpose: To elucidate the roles and competitive interplay of Enhancer of Zeste Homolog 1 (EZH1) and Enhancer of Zeste Homolog 2 (EZH2) in promoting oral squamous cell carcinoma (OSCC) progression. Materials and methods: Bioinformatics analysis was
Kan Li +6 more
doaj +1 more source
Predicting the functional impact of protein mutations: application to cancer genomics
Nucleic Acids Research, 2011 As large-scale re-sequencing of genomes reveals many protein mutations, especially in human cancer tissues, prediction of their likely functional impact becomes important practical goal.
B. Reva, Yevgeniy Antipin, C. Sander
semanticscholar +1 more source
Immunology, EarlyView.A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley +1 more source
Cosmovision as Cognitive Technology: The Case of Mesoamerican Medicinal Knowledge
Topics in Cognitive Science, EarlyView.Abstract We examine the use of cognitive technologies in the acquisition and retention of botanical and medicinal knowledge. We focus on the Cruz‐Badianus codex, a 16th‐century Nahua (Aztec) herbarium which discusses the use of plants for a range of illnesses.
Johan De Smedt, Helen De Cruz
wiley +1 more source
Is the Shroud of Turin in Relation to the Old Jerusalem Historical Earthquake?
, 2015 Phillips and Hedges suggested, in the scientific magazine Nature (1989), that neutron radiation could be liable of a wrong radiocarbon dating, while proton radiation could be responsible of the Shroud body image formation. On the other hand, no plausible
A Carpinteri +30 more
core +1 more source
Women in space: A review of known physiological adaptations and health perspectives
Experimental Physiology, EarlyView.Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford +4 more
wiley +1 more source
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Experimental Physiology, EarlyView.Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
Exploring somatic mutations in cancer with the COSMIC database and analysis tools
, 2022 openalex +1 more source