Results 61 to 70 of about 194,869 (207)
Network-based stratification of tumor mutations. [PDF]
, 2013 Many forms of cancer have multiple subtypes with different causes and clinical outcomes. Somatic tumor genome sequences provide a rich new source of data for uncovering these subtypes but have proven difficult to compare, as two tumors rarely share the ...
Carter, Hannah +4 more
core +3 more sources
Topography of mutational signatures in human cancer
Cell Reports, 2023 Summary: The somatic mutations found in a cancer genome are imprinted by different mutational processes. Each process exhibits a characteristic mutational signature, which can be affected by the genome architecture.
Burçak Otlu +6 more
doaj
Whole exome sequencing in the rat
BMC Genomics, 2018 Background The rat genome was sequenced in 2004 with the aim to improve human health altered by disease and environmental influences through gene discovery and animal model validation.
Julie F. Foley +15 more
doaj +1 more source
Cell line name recognition in support of the identification of synthetic lethality in cancer from text [PDF]
, 2015 Motivation: The recognition and normalization of cell line names in text is an important task in biomedical text mining research, facilitating for instance the identification of synthetically lethal genes from the literature.
Ginter, Filip +5 more
core +2 more sources
PanCNV Explorer: A pan-cancer database for copy number variations.
medRxivIntroduction: Copy number variations (CNVs) are structural genomic alterations that involve changes in the number of copies of specific DNA regions.
Kevin Kornrumpf, Jürgen Dönitz
semanticscholar +1 more source
bioRxiv, 2023 Structural features of proteins capture underlying information about protein evolution and function, which enhances the analysis of proteomic and transcriptomic data.
Nicole Zatorski +9 more
semanticscholar +1 more source
Journal of Translational Medicine, 2022 Kidney transplantation is a lifesaving option for patients with end-stage kidney disease. In Taiwan, urothelial carcinoma (UC) is the most common de novo cancer after kidney transplantation (KT). UC has a greater degree of molecular heterogeneity than do
Lee-Moay Lim +9 more
doaj +1 more source
Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
ANIA:ANnotation and Integrated Analysis of the 14-3-3 interactome [PDF]
, 2014 The dimeric 14-3-3 proteins dock onto pairs of phosphorylated Ser and Thr residues on hundreds of proteins, and thereby regulate many events in mammalian cells.
Baskaran +51 more
core +2 more sources
Intrinsic Base Substitution Patterns in Diverse Species Reveal Links to Cancer and Metabolism.
Genetics, 2022 Analyses of large-scale cancer sequencing data have revealed that mutagenic processes can create distinctive patterns of base substitutions, called mutational signatures.
Suzana P. Gelova +3 more
semanticscholar +1 more source