Results 71 to 80 of about 277,677 (243)
Identification of candidate genes for lung cancer somatic mutation test kits
Genetics and Molecular Biology, 2013 Over the past three decades, mortality from lung cancer has sharply and continuously increased in China, ascending to the first cause of death among all types of cancer.
Yong Chen +4 more
doaj +1 more source
ANIA:ANnotation and Integrated Analysis of the 14-3-3 interactome [PDF]
, 2014 The dimeric 14-3-3 proteins dock onto pairs of phosphorylated Ser and Thr residues on hundreds of proteins, and thereby regulate many events in mammalian cells.
Baskaran +51 more
core +2 more sources
bioRxiv, 2023 Structural features of proteins capture underlying information about protein evolution and function, which enhances the analysis of proteomic and transcriptomic data.
Nicole Zatorski +9 more
semanticscholar +1 more source
Mutational landscape differences between young-onset and older-onset breast cancer patients
BMC Cancer, 2020 Background The incidence of breast cancer among young women (aged ≤40 years) has increased in North America and Europe. Fewer than 10% of cases among young women are attributable to inherited BRCA1 or BRCA2 mutations, suggesting an important role for ...
Nicole E. Mealey +6 more
doaj +1 more source
Topography of mutational signatures in human cancer
Cell Reports, 2023 Summary: The somatic mutations found in a cancer genome are imprinted by different mutational processes. Each process exhibits a characteristic mutational signature, which can be affected by the genome architecture.
Burçak Otlu +6 more
doaj
Whole exome sequencing in the rat
BMC Genomics, 2018 Background The rat genome was sequenced in 2004 with the aim to improve human health altered by disease and environmental influences through gene discovery and animal model validation.
Julie F. Foley +15 more
doaj +1 more source
New Lung Cancer Panel for High-Throughput Targeted Resequencing [PDF]
Genomics & Informatics, 2014 We present a new next-generation sequencing-based method to identify somatic mutations of lung cancer. It is a comprehensive mutation profiling protocol to detect somatic mutations in 30 genes found frequently in lung adenocarcinoma.
Eun-Hye Kim +5 more
doaj +1 more source
Cancer3D: understanding cancer mutations through protein structures. [PDF]
, 2014 The new era of cancer genomics is providing us with extensive knowledge of mutations and other alterations in cancer. The Cancer3D database at http://www.cancer3d.org gives an open and user-friendly way to analyze cancer missense mutations in the context
Godzik, Adam +2 more
core +1 more source
PanCNV Explorer: A pan-cancer database for copy number variations.
medRxivIntroduction: Copy number variations (CNVs) are structural genomic alterations that involve changes in the number of copies of specific DNA regions.
Kevin Kornrumpf, Jürgen Dönitz
semanticscholar +1 more source
Intrinsic Base Substitution Patterns in Diverse Species Reveal Links to Cancer and Metabolism.
Genetics, 2022 Analyses of large-scale cancer sequencing data have revealed that mutagenic processes can create distinctive patterns of base substitutions, called mutational signatures.
Suzana P. Gelova +3 more
semanticscholar +1 more source