Results 41 to 50 of about 563 (201)
Solubilization of drugs. Formulation development perspective
This dissertation discusses some aspects of the solubilization of drugs from the perspective of the formulator. Chapter I emphasizes the importance of this research as well as the study of the practical aspects of aqueous solubilization of drugs.
Alvarez-Nunez, Fernando Antonio
core +4 more sources
Thermodynamic study of the solubility of triclocarban in ethanol + propylene glycol mixtures
By using the van't Hoff and Gibbs equations the apparent thermodynamic functions Gibbs energy, enthalpy, and entropy of solution for triclocarban in ethanol + propylene glycol mixtures were evaluated from solubility data determined at temperatures from ...
Andres R. Holguín +2 more
doaj +1 more source
733751Purpose: Binary water - ethanol mixtures, by mimicking a clinically relevant medium’s polarity-driven extraction strength, facilitate experimental modeling of patient exposure to chemicals which can potentially leach from a plastic material for ...
Egert, T., Langowski, Horst-Christian
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Celecoxib (CXB) is a COX‐2‐selective nonsteroidal anti‐inflammatory drug used to control pain and various inflammatory conditions. CXB has limited oral bioavailability and a slow dissociation rate due to its poor water solubility. In order to enhance the oral bioavailability of CXB and reduce the frequency of administration, the present study was aimed
Bazigha K. Abdul Rasool +4 more
wiley +1 more source
Poor solubility of new antifungal of 1,2,4-triazole class (S-119)—a structural analogue of fluconazole in aqueous media was estimated. The solubility improvement using different excipients: biopolymers (PEGs, PVP), surfactants (Brij S20, pluronic F-127 ...
Tatyana V. Volkova +2 more
doaj +1 more source
New phase phenomena in ternary systems at high pressures - Cosolvency and miscibility windows up to 100 MPay [PDF]
For selected systems CO 2 + alkan-1-ol + alkane, new high-pressure phase phenomena have been found. Isobaric cosolvency effects and isothermal miscibility windows are presented phenomenologically and numerically. Additionally, rules for the occurrence of
Arndt L Scheidgenz, Gerhard M Schneider
core
This work reports the ability of cosolvency and activity coefficient models in the prediction of drugs solubility in methanol + water mixtures by choosing a minimum number of experimental data point. For this purpose, the available solubility datasets of
Parisa Jafari (5447729) +1 more
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Thermodynamic study of the solubility of sodium naproxen in some ethanol + water mixtures
By using the van't Hoff and Gibbs equations the apparent thermodynamic functions Gibbs energy, enthalpy, and entropy of solution for sodium naproxen in ethanol + water cosolvent mixtures, were evaluated from solubility data determined at temperatures ...
Daniel R. Delgado +4 more
doaj +1 more source
In this work, solubility data of 1,5-pentanediamine adipate dihydrate in binary solvent systems of water + methanol, water + ethanol and water + N,N-dimethylformamide were experimentally measured via a static gravimetric method in the temperature range ...
Liang Li +8 more
doaj +1 more source
Composite films of cellulose nanofibers (CNFs) and poly(methyl methacrylate) (PMMA) are fabricated typically by solution-casting using an organic solvent (e.g., chloroform) that can dissolve PMMA.
Iwata, Tadahisa +4 more
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