Results 61 to 70 of about 563 (201)

A Study on Solubilization of Poorly Soluble Drugs by Cyclodextrins and Micelles: Complexation and Binding Characteristics of Sulfamethoxazole and Trimethoprim

open access: yesThe Scientific World Journal, Volume 2012, Issue 1, 2012., 2012
The present study is focused on the characterization of solubilization of poorly soluble drugs, that is, sulfamethoxazole (SMX) and trimethoprim (TMP) by cyclodextrins (α‐, β‐, and γ‐CDs) and anionic surfactant sodium dodecyl sulfate (SDS). The phase solubility diagrams drawn from UV spectral measurements are of the AL type and indicate an enhancement ...
Sinem Göktürk   +5 more
wiley   +1 more source

Adaptive Elastin‐Like Hydrogel with Unidirectional and Controllable Anisotropic Actuation for Soft Robotics and Tissue Engineering

open access: yesAdvanced Materials Technologies, Volume 10, Issue 17, September 4, 2025.
Fiber‐reinforced elastin‐like tubular scaffolds are engineered to achieve anisotropic and reversible actuation under external stimuli. By adjusting fiber's angle, actuation behavior is finely tuned, enabling distinct actuation responses, even within different regions of the same scaffold.
Federica Sallustio   +7 more
wiley   +1 more source

Drug Solubility: Importance and Enhancement Techniques

open access: yesInternational Scholarly Research Notices, Volume 2012, Issue 1, 2012., 2012
Solubility, the phenomenon of dissolution of solute in solvent to give a homogenous system, is one of the important parameters to achieve desired concentration of drug in systemic circulation for desired (anticipated) pharmacological response. Low aqueous solubility is the major problem encountered with formulation development of new chemical entities ...
Ketan T. Savjani   +5 more
wiley   +1 more source

Dissolution Thermodynamics of the Solubility of Sulfamethazine in (Acetonitrile + 1-Propanol) Mixtures

open access: yesPharmaceuticals
Background: Solubility is one of the most important parameters in the research and development processes of the pharmaceutical industry. In this context, cosolubility is one of the most used strategies to improve the solubility of poorly soluble drugs ...
Daniel Ricardo Delgado   +4 more
doaj   +1 more source

Liquisolid Technology: Preparation, Characterization and Applications [PDF]

open access: yes, 2020
With the advent of high throughput screening, drugs are emerging to be more lipophilic and less hydrophilic. Liquisolid Technology aims at solubility enhancement of such entities via cosolvency concept in a relatively minimalistic setup where there is no
Gorle, Ashish Prakash   +1 more
core   +1 more source

Prediction of a Broad Spectra of Membrane Morphologies Through a New NIPS Thermo‐Kinetic Model

open access: yesAdvances in Polymer Technology, Volume 2025, Issue 1, 2025.
This work presents a novel semiempirical mathematical approach consisting of a coupled thermo‐kinetic model as valuable tool for predicting the polymeric fraction profile of membranes synthesized by nonsolvent induced phase separation (NIPS). Equilibrium binodal curves (BCs) of the system component were incorporated to the Fick’s diffusive kinetic ...
Marta Romay   +3 more
wiley   +1 more source

Solubility and Apparent Specific Volume of Sucrose in Some Aqueous Polyethylene Glycol Mixtures at 298.2 K [PDF]

open access: yesPharmaceutical Sciences, 2018
Background: Sucrose is the most widely used sweetener in food and pharmaceuticals. Quantitative solubility values of this excipient in aqueous polyethylene glycol (PEG) mixtures is not abundant.
Dario A Tinjaca   +5 more
doaj   +1 more source

Lipid Horizons: Recent Advances and Future Prospects in LBDDS for Oral Administration of Antihypertensive Agents

open access: yesInternational Journal of Hypertension, Volume 2024, Issue 1, 2024.
The lipid‐based drug delivery system (LBDDS) is a well‐established technique that is anticipated to bring about comprehensive transformations in the pharmaceutical field, impacting the management and administration of drugs, as well as treatment and diagnosis.
Preeti   +10 more
wiley   +1 more source

THERMODYNAMIC STUDY OF THE SOLUBILITY OF SODIUM SULFADIAZINE IN SOME ETHANOL + WATER COSOLVENT MIXTURES

open access: yesVitae, 2010
Sodium sulfadiazine (SD-Na) is a drug extensively used for the treatment of certain infections caused by several kinds of microorganisms. Although SD-Na is widely used nowadays in therapeutics, the physicochemical information about their aqueous ...
Daniel R. DELGADO, Fleming MARTÍNEZ R.
doaj  

Effect of Ethanol on the Equilibrium Solubility and Apparent Specific Volume of Sodium Sulfamethazine in Aqueous Systems at Several Temperatures

open access: yesLiquids
The main objective of this research was to determine and correlate the equilibrium solubility of sodium sulfamethazine (NaSMT) in several {ethanol (1) + water (2)} mixtures reported in mass/volume and mass/mass percentages at different temperatures, as ...
Daniel Ricardo Delgado   +5 more
doaj   +1 more source

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