Results 61 to 70 of about 563 (201)
The present study is focused on the characterization of solubilization of poorly soluble drugs, that is, sulfamethoxazole (SMX) and trimethoprim (TMP) by cyclodextrins (α‐, β‐, and γ‐CDs) and anionic surfactant sodium dodecyl sulfate (SDS). The phase solubility diagrams drawn from UV spectral measurements are of the AL type and indicate an enhancement ...
Sinem Göktürk +5 more
wiley +1 more source
Fiber‐reinforced elastin‐like tubular scaffolds are engineered to achieve anisotropic and reversible actuation under external stimuli. By adjusting fiber's angle, actuation behavior is finely tuned, enabling distinct actuation responses, even within different regions of the same scaffold.
Federica Sallustio +7 more
wiley +1 more source
Drug Solubility: Importance and Enhancement Techniques
Solubility, the phenomenon of dissolution of solute in solvent to give a homogenous system, is one of the important parameters to achieve desired concentration of drug in systemic circulation for desired (anticipated) pharmacological response. Low aqueous solubility is the major problem encountered with formulation development of new chemical entities ...
Ketan T. Savjani +5 more
wiley +1 more source
Background: Solubility is one of the most important parameters in the research and development processes of the pharmaceutical industry. In this context, cosolubility is one of the most used strategies to improve the solubility of poorly soluble drugs ...
Daniel Ricardo Delgado +4 more
doaj +1 more source
Liquisolid Technology: Preparation, Characterization and Applications [PDF]
With the advent of high throughput screening, drugs are emerging to be more lipophilic and less hydrophilic. Liquisolid Technology aims at solubility enhancement of such entities via cosolvency concept in a relatively minimalistic setup where there is no
Gorle, Ashish Prakash +1 more
core +1 more source
Prediction of a Broad Spectra of Membrane Morphologies Through a New NIPS Thermo‐Kinetic Model
This work presents a novel semiempirical mathematical approach consisting of a coupled thermo‐kinetic model as valuable tool for predicting the polymeric fraction profile of membranes synthesized by nonsolvent induced phase separation (NIPS). Equilibrium binodal curves (BCs) of the system component were incorporated to the Fick’s diffusive kinetic ...
Marta Romay +3 more
wiley +1 more source
Solubility and Apparent Specific Volume of Sucrose in Some Aqueous Polyethylene Glycol Mixtures at 298.2 K [PDF]
Background: Sucrose is the most widely used sweetener in food and pharmaceuticals. Quantitative solubility values of this excipient in aqueous polyethylene glycol (PEG) mixtures is not abundant.
Dario A Tinjaca +5 more
doaj +1 more source
The lipid‐based drug delivery system (LBDDS) is a well‐established technique that is anticipated to bring about comprehensive transformations in the pharmaceutical field, impacting the management and administration of drugs, as well as treatment and diagnosis.
Preeti +10 more
wiley +1 more source
Sodium sulfadiazine (SD-Na) is a drug extensively used for the treatment of certain infections caused by several kinds of microorganisms. Although SD-Na is widely used nowadays in therapeutics, the physicochemical information about their aqueous ...
Daniel R. DELGADO, Fleming MARTÍNEZ R.
doaj
The main objective of this research was to determine and correlate the equilibrium solubility of sodium sulfamethazine (NaSMT) in several {ethanol (1) + water (2)} mixtures reported in mass/volume and mass/mass percentages at different temperatures, as ...
Daniel Ricardo Delgado +5 more
doaj +1 more source

