Results 71 to 80 of about 486 (202)

Solubility Enhancement of Etoricoxib by Cosolvency Approach

International Scholarly Research Notices, Volume 2012, Issue 1, 2012., 2012
The purpose of the present study was to examine and compare the cosolvency using three different cosolvents, namely PEG 400, PG, and glycerin on the aqueous solubility enhancement of a poorly aqueous soluble drug, etoricoxib, since solubilization of nonpolar drugs constitutes one of the important tasks in the formulation design of liquid dosage forms ...
Amit Kumar Nayak, Prachi Prava Panigrahi, A. Dkhissi, L. K. Shrestha, N. A. Vodolazkaya   +4 more
wiley   +1 more source

Prediction of a Broad Spectra of Membrane Morphologies Through a New NIPS Thermo‐Kinetic Model

Advances in Polymer Technology, Volume 2025, Issue 1, 2025.
This work presents a novel semiempirical mathematical approach consisting of a coupled thermo‐kinetic model as valuable tool for predicting the polymeric fraction profile of membranes synthesized by nonsolvent induced phase separation (NIPS). Equilibrium binodal curves (BCs) of the system component were incorporated to the Fick’s diffusive kinetic ...
Marta Romay, Ane Urtiaga, Nazely Diban, Nasir Ahmad   +3 more
wiley   +1 more source

A Novel Paclitaxel Microemulsion Containing a Reduced Amount of Cremophor EL: Pharmacokinetics, Biodistribution, and In Vivo Antitumor Efficacy and Safety

BioMed Research International, Volume 2011, Issue 1, 2011., 2011
The purpose of this study was to prepare a novel paclitaxel (PTX) microemulsion containing a reduced amount of Cremophor EL (CrEL) which had similar pharmacokinetics and antitumor efficacy as the commercially available PTX injection, but a significantly reduced allergic effect due to the CrEL.
Ying Wang, Ke-Chun Wu, Bing-Xiang Zhao, Xin Zhao, Xin Wang, Su Chen, Shu-Fang Nie, Wei-San Pan, Xuan Zhang, Qiang Zhang, Mark J. McKeage   +10 more
wiley   +1 more source

Molecular heterogeneity in aqueous cosolvent systems [PDF]

The Journal of Chemical Physics, 2020
Aqueous cosolvent systems (ACoSs) are mixtures of small polar molecules such as amides, alcohols, dimethyl sulfoxide, or ions in water. These liquids have been the focus of fundamental studies due to their complex intermolecular interactions as well as their broad applications in chemistry, medicine, and materials science.
Kwang-Im Oh, Carlos R. Baiz
openaire   +2 more sources

Lipid Horizons: Recent Advances and Future Prospects in LBDDS for Oral Administration of Antihypertensive Agents

International Journal of Hypertension, Volume 2024, Issue 1, 2024.
The lipid‐based drug delivery system (LBDDS) is a well‐established technique that is anticipated to bring about comprehensive transformations in the pharmaceutical field, impacting the management and administration of drugs, as well as treatment and diagnosis.
Preeti, Sharda Sambhakar, Rohit Malik, Saurabh Bhatia, Ahmed Al Harrasi, Renu Saharan, Geeta Aggarwal, Suresh Kumar, Renu Sehrawat, Chanchal Rani, Emanuele Pivetta   +10 more
wiley   +1 more source

A Review of Multidimensional, Multifluid, Intermediate‐Scale Experiments: Flow Behavior, Saturation Imaging, and Tracer Detection and Quantification

Vadose Zone Journal, Volume 6, Issue 3, Page 610-637, August 2007., 2007
A review is presented of original multidimensional, intermediate‐scale experiments involving nonaqueous phase liquid (NAPL) flow behavior, imaging, and detection and quantification with solute tracers. In a companion paper (Oostrom et al., 2006a), experiments related to aqueous dissolution and enhanced remediation were discussed.
M. Oostrom, J. H. Dane, T. W. Wietsma
wiley   +1 more source

Solubility and Apparent Specific Volume of Sucrose in Some Aqueous Polyethylene Glycol Mixtures at 298.2 K [PDF]

Pharmaceutical Sciences, 2018
Background: Sucrose is the most widely used sweetener in food and pharmaceuticals. Quantitative solubility values of this excipient in aqueous polyethylene glycol (PEG) mixtures is not abundant.
Dario A Tinjaca, Maria M Muñoz, Elaheh Rahimpour, Abolghasem Jouyban, Fleming Martinez, William E Acree Jr   +5 more
doaj   +1 more source

THERMODYNAMIC STUDY OF THE SOLUBILITY OF SODIUM SULFADIAZINE IN SOME ETHANOL + WATER COSOLVENT MIXTURES

Vitae, 2010
Sodium sulfadiazine (SD-Na) is a drug extensively used for the treatment of certain infections caused by several kinds of microorganisms. Although SD-Na is widely used nowadays in therapeutics, the physicochemical information about their aqueous ...
Daniel R. DELGADO, Fleming MARTÍNEZ R.
doaj  

Dissolution Thermodynamics and Preferential Solvation of Phenothiazine in Some Aqueous Cosolvent Systems

Liquids
Published equilibrium mole fraction solubilities of phenothiazine in ethanol, propylene glycol and water as mono-solvents at several temperatures were investigated to find standard apparent thermodynamic quantities of dissolution mixing and solvation ...
Fleming Martínez, María Ángeles Peña, Abolghasem Jouyban   +2 more
doaj   +1 more source

Solubility of Sildenafil Citrate in Polyethylene Glycol 200 + Water Mixtures at 293.2-313.2 K [PDF]

Pharmaceutical Sciences
Background: In the current investigation, the evaluation of model congruence alongside experimental determinations of the solid-liquid phase boundary concerning sildenafil citrate within aqueous binary blends of polyethylene glycol 200 has been conducted.
Homa Rezaei, Abolghasem Jouyban
doaj   +1 more source