Solubility of mesalazine in pseudo-binary mixtures of choline chloride/ethylene glycol deep eutectic solvent and water at 293.15 K to 313.15 K [PDF]
BMC Chemistry, 2023 Mesalazine (5-ASA) is a medication utilized to treat inflammatory bowel diseases involving ulcerative colitis and Crohn’s disease. Mesalazine has fewer side effects but the low solubility and bioavailability of it is responsible for its delayed onset of ...
Elina Armani +5 more
doaj +3 more sources
Measurement and correlation of solubility data for deferiprone in propylene glycol and 2-propanol at different temperatures [PDF]
Heliyon, 2023 This investigation dealt with the thermodynamic properties, saturated solubility values, and solvation behavior of deferiprone as an oral iron chelator agent in non-aqueous mixtures of propylene glycol and 2-propanol using experimental measurements and ...
Homa Rezaei +3 more
doaj +2 more sources
Solubility and thermodynamic study of deferiprone in propylene glycol and ethanol mixture [PDF]
BMC Chemistry, 2023 This work aims to obtain the solubility, density and thermodynamic parameters of deferiprone in propylene glycol and ethanol. For this purpose, a shake-flask technique was applied for solid–liquid equilibration and the spectrophotometry method was ...
Samira Radmand +4 more
doaj +2 more sources
Solubility of Cinnarizine in (Transcutol + Water) Mixtures: Determination, Hansen Solubility Parameters, Correlation, and Thermodynamics [PDF]
Molecules, 2021 Between 293.2 and 313.2 K and at 0.1 MPa, the solubility of the weak base, cinnarizine (CNZ) (3), in various {Transcutol-P (TP) (1) + water (2)} combinations is reported.
Faiyaz Shakeel +3 more
doaj +2 more sources
Investigation of the solubility and thermodynamics of salicylic acid in 2-propanol and ethylene glycol/propylene glycol binary solvent mixtures at (293.15 to 313.15) K [PDF]
BMC ChemistryThis study aimed to measure both the solubility and thermodynamics of salicylic acid in binary solvent mixtures of (2-propanol + ethylene glycol) and (2-propanol + propylene glycol) at different temperatures in the range of 293.2–313.2 K.
Fatemeh Dabagh +6 more
doaj +2 more sources
Experimental measurement, thermodynamic analysis, and mathematical modeling for budesonide solubility in 1-propanol + water mixtures at T = (293.2 to 313.2) K [PDF]
BMC ChemistryBudesonide (BDS) a steroid-based anti-inflammatory drug widely prescribed for various diseases, has a low aqueous solubility. In this study, we investigated cosolvency approach to study the thermodynamic specifications related to the solubility of BDS at
Esmaeil Mohammadian +3 more
doaj +2 more sources
Solubility of 5-nitroisophthalic acid in pseudo-binary mixtures containing water and betaine-based deep eutectic solvents: effect of benzene ring substituents in the benzene carboxylic acid-based compounds on their solubility values [PDF]
BMC ChemistryThis work aimed to report the equilibrium solubility of 5-nitroisophthalic acid (5-NIPA) in solvent mixtures of betaine/propylene glycol (Bet/PG) deep eutectic solvent (DES) (1:5 molar ratio) + water, betaine/ethylene glycol (Bet/EG) DES (1:3 molar ratio)
Parisa Jafari +3 more
doaj +2 more sources
Thermodynamic Study of Deferiprone Dissolution in Polyethylene Glycol 400 and 2-Propanol Mixture [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2023 In the current study, the solubility and density of deferiprone were determined in the polyethylene glycol (PEG) 400 and 2-propanol mixtures at 293.2 – 313.2 K using a shake-flask method before a spectrophotometric method.
Mahsa Ahmadi +4 more
doaj +1 more source
Solubility of Bosentan in Polyethylene Glycol 400 + Water Mixtures: Experimental and Mathematical Computations [PDF]
Pharmaceutical Sciences, 2023 Background: To discover the optimal solvent amounts for using in a particular application, it is vital to achieve some useful information in regard with suitable neat or mixed solvent and drugs equilibrium solubility in them.
Parisa Jafari +2 more
doaj +1 more source
Budesonide Solubility in 2-Propanol+ Water Mixtures at T = (293.2 to 313.2) K: Experimental Measurement, Thermodynamic Analysis and Mathematical Modeling [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2023 A shake-flask method was used to investigate the solubility and thermodynamic properties of budesonide (BDS) in the temperature scope of 293.2-313.22 K in aqueous mixtures of 2-propanol.
Esmail Mohamadian +4 more
doaj +1 more source