Results 11 to 20 of about 6,892,179 (134)
Thermodynamic solubility of piroxicam in propylene glycol + water mixtures at 298.2-323.2 K: Data report and modeling [PDF]
Journal of the Serbian Chemical Society, 2015 The solubility of piroxicam (66 data points) in binary mixtures of propylene glycol (PG) + water at six different temperatures which ranged from 298.2 K to 323.2 K were reported.
Soltanpour Shahla, Bastami Zahra
doaj +2 more sources
Solubility Study of Acetylsalicylic Acid in Ethanol + Water Mixtures: Measurement, Mathematical Modeling, and Stability Discussion. [PDF]
AAPS PharmSciTech, 2021 Solubility determination of poorly water-soluble drugs is pivotal for formulation scientists when they want to develop a liquid formulation. Performing such a test with different ratios of cosolvents with water is time-consuming and costly.
Nokhodchi A +8 more
europepmc +2 more sources
Employment of Alginate Floating In Situ Gel for Controlled Delivery of Celecoxib: Solubilization and Formulation Studies. [PDF]
Biomed Res Int, 2020 Celecoxib (CXB) is a COX‐2‐selective nonsteroidal anti‐inflammatory drug used to control pain and various inflammatory conditions. CXB has limited oral bioavailability and a slow dissociation rate due to its poor water solubility. In order to enhance the oral bioavailability of CXB and reduce the frequency of administration, the present study was aimed
Abdul Rasool BK +3 more
europepmc +2 more sources
A fugacity approach for generating a landfill gas trace component source term. [PDF]
, 2005 The quality of risk assessment output is determined by the input data used in environmental distribution, dispersion and exposure models. Whilst recent focus has been on the development of regulatory exposure assessment models for landfills, risk ...
Rosevear, Alan +4 more
core +7 more sources
BioMed Research International, Volume 2023, Issue 1, 2023., 2023 Nanoemulgels are considered as potential and ideal drug delivery systems for the transdermal administration of poorly soluble drugs like lornoxicam. Their intrinsic characteristics, such as small globule size as well as excipient type, make transdermal passage of the drug easier.
Muhammad Shafiq +9 more
wiley +1 more source
Advanced Science, Volume 9, Issue 36, December 28, 2022., 2022 Computer simulations predict supramolecular formation of pyrazole‐modified monomers. Based on the simulations, selected monomers are used in the template‐free and facile upscalable precipitation polymerization to obtain anisotropic microgels (from spherical, raspberry‐like to dumbbell‐like).
Frédéric Grabowski +6 more
wiley +1 more source
Advances in Pharmacological and Pharmaceutical Sciences, Volume 2022, Issue 1, 2022., 2022 Purpose. The biopharmaceutics classification system places rosuvastatin calcium in class II has a low and fluctuating oral bioavailability. The research focus is to maximize rosuvastatin calcium solubility in water and dissolution rate by employing and combining various hydrotropic agents to make a solid dispersion using solvent evaporation techniques.
Hezha Abdullah Ali +2 more
wiley +1 more source
Advanced Engineering Materials, Volume 23, Issue 11, November 2021., 2021 Ternary nanoswitches are realized using PMMA‐b‐PNIPMAM diblock copolymer thin films. Three distinct film states (off, on, and standby) are successfully prepared by the combination of amphiphilicity and co‐nonsolvency effect. The exposure to N2, pure water vapor, and mixed 90 vol% water/10 vol% acetone vapor switches the films between dried, hydrated ...
Christina Geiger +10 more
wiley +1 more source
, 2023 Cosolvency is an intriguing thermodynamic phenomenon. However, the lack of theoretical research restricts its development and its further applications.
Dongbo Wang +17 more
core +1 more source
Microarray Patches: Poking a Hole in the Challenges Faced When Delivering Poorly Soluble Drugs
Advanced Functional Materials, Volume 31, Issue 1, January 4, 2021., 2021 This review explores the delivery of hydrophobic compounds to the skin using microarray patches (MAPs). Initially designed to load low doses of hydrophilic and potent therapeutic agents, MAPs are now increasingly considered a viable strategy for the delivery of therapeutically relevant doses of poorly soluble drugs. This somewhat unexpected application
Alejandro J. Paredes +11 more
wiley +1 more source