Results 31 to 40 of about 275 (175)

Enthalpy-entropy compensation analysis of the triclocarban dissolution process in some {1,4-dioxane (1)?+?water (2)} mixtures

, 2018
The equilibrium solubility of triclocarban in {1,4-dioxane (1) + water (2)} mixtures at 293.15 K to 313.15 K was reported. Mole fraction solubility increases continuously from neat water to neat 1,4-dioxane at all temperatures.
Jouyban A., Delgado, Daniel ricardo, Almanza O.A., Mogollon Waltero, Edgar mauricio, Peña M.Á., Ortiz C.P., Martínez F.   +6 more
core   +3 more sources

Measurement and Correlation of the Solubility of 2Mercapto-1,3,4-thiadiazol in Aqueous Binary Solvent Mixtures

, 2022
The solubility of 2-mercapto-1,3,4-thiadiazol (MTD) in four kinds of aqueous mixed solvents including water + (methanol, ethanol, n-propanol, and acetone) was measured by the static gravimetric method in a temperature range of 278.15–323.15 K.
Weichun Feng, Shuai Yu, Yunlong Gao (2098291), Yuanchang Ma, Wenguo Xing, Weichun Feng (1581028), Wenguo Xing (11501348), Hongcheng Li (6869378), Fumin Xue (8694675), Hongcheng Li, Xujie Gao, Zihao Wang (845023), Shuai Yu (1863535), Zihao Wang, Fumin Xue, Xujie Gao (5424713), Yuanchang Ma (11501345), Yunlong Gao   +17 more
core   +1 more source

Preferential Solvation Study of the Synthesized Aldose Reductase Inhibitor (SE415) in the {PEG 400 (1) + Water (2)} Cosolvent Mixture and GastroPlus-Based Prediction. [PDF]

ACS Omega, 2022
(Z)-N-Benzyl-2-{2,4-dioxo-5-(4-prop-2-yl-1-yloxyl)­benzylidene)­thiazolin-3-yl)}­acetamide (SE415) is a novel aldose reductase inhibitor used in the management of diabetes mellitus (DM) and associated complications. Herein, the drug was solubilized (mole
Hussain A, Hussain A, Altamimi MA, Afzal O, Altamimi ASA, Ali A, Ali A, Martinez F, Mohd Siddique MU, Acree WE, Jouyban A.   +10 more
europepmc   +2 more sources

Solubility and thermodynamics of celecoxib in N-methyl-2-pyrrolidone and (ethanol, 1-propanol) binary solvent mixtures at (293.15 to 313.15) K

, 2023
This study presents solubility determination and the thermodynamic analysis of celecoxib (CXB) in two kinds of solvent mixtures of N-methyl-2-pyrrolidone (NMP) + ethanol and NMP + 1-propanol at various temperatures (293.15–313.15 K).
Behrouz Seyfinejad (14333717), Fleming Martinez (11892659), Atefeh Sheikhi-Sovari (14333714), Abolghasem Jouyban (578282), Mohammad Barzegar-Jalali (4812870), Hongkun Zhao (2852867)   +5 more
core   +1 more source

Solubility of Sildenafil Citrate in Polyethylene Glycol 200 + Water Mixtures at 293.2-313.2 K [PDF]

Pharmaceutical Sciences
Background: In the current investigation, the evaluation of model congruence alongside experimental determinations of the solid-liquid phase boundary concerning sildenafil citrate within aqueous binary blends of polyethylene glycol 200 has been conducted.
Homa Rezaei, Abolghasem Jouyban
doaj   +1 more source

Increasing the Equilibrium Solubility of Meloxicam in Aqueous Media by Using Dimethyl Sulfoxide as a Cosolvent: Correlation, Dissolution Thermodynamics and Preferential Solvation [PDF]

, 2022
Meloxicam is widely prescribed as an analgesic and anti-inflammatory drug in human therapeutics. Owing the very low aqueous solubility of meloxicam, this property has been studied in dimethyl sulfoxide (DMSO)-aqueous solvent systems at several ...
Fleming Martínez, Ovidio A. Almanza, Tinjacá, Darío, M. Ángeles Peña, Almanza, Ovidio A., Abolghasem Jouyban, Darío A. Tinjacá, William E. Acree, Martínez, Fleming, Jouyban, Abolghasem, Peña, María Á., Acree, William E. (William Eugene)   +11 more
core   +1 more source

The Influence of Cosolvent Polarity on the Flow Properties of Hydroalcoholic Gels. Empirical Models

Chemical and Pharmaceutical Bulletin, 2005
The aim of this study was to investigate the influence of cosolvent polarity on the rheological flow properties of aqueous and hydroalcoholic gels obtained from the Carbopol Ultrez 10 base and used for topical applications. Specifically, we have examined the effect of pH (range 4.0--7.0) on the consistency and flow properties of dispersed systems in ...
Jiménez, María Magdalena, Fresno, María José, Ramírez, Alain   +2 more
openaire   +3 more sources

Solubility of Different Polymorphs of Drugs in Mono- and Mixed-Solvents at Various Temperatures [PDF]

Pharmaceutical Sciences
Background: Solubility of drugs is an important issue in pharmaceutical industry and the solubility of polymorphs play a critical role in dealing with the solubility issue.
Abolghasem Jouyban
doaj   +1 more source

Phase equilibrium measurements and thermodynamic modeling of {CO2 + diethyl succinate + cosolvent} systems [PDF]

Fluid Phase Equilibria, 2019
This work reports experimental phase equilibrium data for the binary systems {CO2(1) + diethyl succinate(2)} and {CO2(1) + ethyl acetate(2)}, and for the ternary systems {CO2(1) + diethyl succinate(2) + ethanol(3)} and {CO2(1) + diethyl succinate(2) + ethyl acetate(3)}.
Amabille Petza Kloc, Eleni Grilla, Claudia A. Capeletto, Maria Papadaki, Marcos L. Corazza   +4 more
openaire   +2 more sources

Physicochemical Characterization and Cyclodextrin Complexation of the Anticancer Drug Lapatinib

Journal of Chemistry, Volume 2017, Issue 1, 2017., 2017
Lapatinib (LAP), the tyrosine kinase inhibitor drug with moderate bioavailability, was characterized in terms of physicochemical properties: acid‐base characteristics, lipophilicity, and solubility. The highly lipophilic nature of the drug and its extremely low water solubility (S0 = 0.82 nM) limit the development of a parenteral formulation.
Gergő Tóth, Ádám Jánoska, Gergely Völgyi, Zoltán-István Szabó, Gábor Orgován, Arash Mirzahosseini, Béla Noszál, Jaime Villaverde   +7 more
wiley   +1 more source