Results 41 to 50 of about 6,892,179 (134)

Drug Solubility: Importance and Enhancement Techniques

International Scholarly Research Notices, Volume 2012, Issue 1, 2012., 2012
Solubility, the phenomenon of dissolution of solute in solvent to give a homogenous system, is one of the important parameters to achieve desired concentration of drug in systemic circulation for desired (anticipated) pharmacological response. Low aqueous solubility is the major problem encountered with formulation development of new chemical entities ...
Ketan T. Savjani, Anuradha K. Gajjar, Jignasa K. Savjani, G. Aktay, Y.-Z. Du, J. Torrado   +5 more
wiley   +1 more source

Solubility and thermodynamic studies of procaine hydrochloride in propylene glycol + 2-propanol binary mixtures at different temperatures

Results in Chemistry
In the present work, the solubility of procaine-HCl was determined in propylene glycol (PG) +2-propanol mixtures at temperatures of 298.2–313.2 K. The maximum solubility of procaine-HCl in mole fraction unit was 1.84 × 10−2 in neat PG at 313.2 K and the ...
Kader Poturcu, Elaheh Rahimpour, Abolghasem Jouyban   +2 more
doaj   +1 more source

Nonadditive CO2 Uptake of Type II Porous Liquids Based on Imine Cages

ChemPhysChem, Volume 26, Issue 12, June 23, 2025.
Type II porous liquids based on porous imine cages (CC13/CC19) show non‐additive CO2 uptake, surpassing ideal volume additivity predictions. Experiments and simulations reveal enhanced gas absorption, with CO2 partitioning into cage pores and solvent.
Lu Lu, Chao‐Wen Chang, Stephen Schuyten, Ankana Roy, David S. Sholl, Ryan P. Lively   +5 more
wiley   +1 more source

1,4-Dioxane cosolvency impacts on trichloroethene dissolution and sorption

, 2019
Solvent stabilizer 1,4-dioxane, an emerging recalcitrant groundwater contaminant, was commonly added to chlorinated solvents such as trichloroethene (TCE), and the impact of co-disposal on contaminant transport processes remains uncertain.
Carroll, Kenneth C., Brusseau, Mark L., Milavec, Justin, Tick, Geoffrey R.   +3 more
core   +1 more source

Prediction of a Broad Spectra of Membrane Morphologies Through a New NIPS Thermo‐Kinetic Model

Advances in Polymer Technology, Volume 2025, Issue 1, 2025.
This work presents a novel semiempirical mathematical approach consisting of a coupled thermo‐kinetic model as valuable tool for predicting the polymeric fraction profile of membranes synthesized by nonsolvent induced phase separation (NIPS). Equilibrium binodal curves (BCs) of the system component were incorporated to the Fick’s diffusive kinetic ...
Marta Romay, Ane Urtiaga, Nazely Diban, Nasir Ahmad   +3 more
wiley   +1 more source

Lipid Horizons: Recent Advances and Future Prospects in LBDDS for Oral Administration of Antihypertensive Agents

International Journal of Hypertension, Volume 2024, Issue 1, 2024.
The lipid‐based drug delivery system (LBDDS) is a well‐established technique that is anticipated to bring about comprehensive transformations in the pharmaceutical field, impacting the management and administration of drugs, as well as treatment and diagnosis.
Preeti, Sharda Sambhakar, Rohit Malik, Saurabh Bhatia, Ahmed Al Harrasi, Renu Saharan, Geeta Aggarwal, Suresh Kumar, Renu Sehrawat, Chanchal Rani, Emanuele Pivetta   +10 more
wiley   +1 more source

Measurement and Correlation of the Solubility of 2Mercapto-1,3,4-thiadiazol in Aqueous Binary Solvent Mixtures

, 2022
The solubility of 2-mercapto-1,3,4-thiadiazol (MTD) in four kinds of aqueous mixed solvents including water + (methanol, ethanol, n-propanol, and acetone) was measured by the static gravimetric method in a temperature range of 278.15–323.15 K.
Weichun Feng, Shuai Yu, Yunlong Gao (2098291), Yuanchang Ma, Wenguo Xing, Weichun Feng (1581028), Wenguo Xing (11501348), Hongcheng Li (6869378), Fumin Xue (8694675), Hongcheng Li, Xujie Gao, Zihao Wang (845023), Shuai Yu (1863535), Zihao Wang, Fumin Xue, Xujie Gao (5424713), Yuanchang Ma (11501345), Yunlong Gao   +17 more
core   +1 more source

Enthalpy-entropy compensation analysis of the triclocarban dissolution process in some {1,4-dioxane (1)?+?water (2)} mixtures

, 2018
The equilibrium solubility of triclocarban in {1,4-dioxane (1) + water (2)} mixtures at 293.15 K to 313.15 K was reported. Mole fraction solubility increases continuously from neat water to neat 1,4-dioxane at all temperatures.
Jouyban A., Delgado, Daniel ricardo, Almanza O.A., Mogollon Waltero, Edgar mauricio, Peña M.Á., Ortiz C.P., Martínez F.   +6 more
core   +2 more sources

Partitioning Behavior of Organic Contaminants in Carbon Storage Environments: A Critical Review

, 2016
Carbon capture and storage is a promising strategy for mitigating the CO2 contribution to global climate change. The large scale implementation of the technology mandates better understanding of the risks associated with CO2 injection into geologic ...
Athanasios K. Karamalidis (1548748), Aniela Burant (2008504), Gregory V. Lowry (382565)   +2 more
core   +1 more source

Facile preparation of optically transparent film of acetylated cellulose nanofiber-reinforced poly(methyl methacrylate) utilizing cosolvency in aqueous ethanol

, 2023
Composite films of cellulose nanofibers (CNFs) and poly(methyl methacrylate) (PMMA) are fabricated typically by solution-casting using an organic solvent (e.g., chloroform) that can dissolve PMMA.
Iwata, Tadahisa, Suzuki, Shiori, Uraki, Yasumitsu, Tanouchi, Ikuto, Taira, Shogo   +4 more
core   +1 more source