Optimizing preservation strategies for deteriorating items with time-varying holding cost and stock-dependent demand [PDF]
, 2020 Aditi Khanna +2 more
openalex +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Simple and Rapid Device for Mercury Detection Based on The Formation of Mercury(II)-Dithizonate on Polytetrafluoroethylene (PTFE) Membrane [PDF]
Journal of Pure and Applied Chemistry Research, 2019 A new analytical device for mercury detection has been developed by doping dithizone on to hydrophobic PTFE (polytetrafluoroethylene) membrane to form a blue dithizone membrane which instantaneously changed to orange color of mercury(II)-dithizonate ...
Hermin Sulistyarti +4 more
doaj
Burden and magnitude of risk in HIV/AIDS in the Colombian health system: a real-world data approach
Infectio, 2021 Aim: To assess the epidemiological situation of people living with HIV and AIDS (PLWHA) in the municipalities and regions of Colombia in 2018. Materials and methods: A cross-sectional study was conducted with secondary data from the High-Cost Diseases ...
Silvia Juliana Trujillo-Cáceres
doaj +1 more source
Cost-effectiveness analysis of the Oncotype DX Breast Recurrence Score test in node-positive early breast cancer [PDF]
, 2022 Vladislav Berdunov +9 more
openalex +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Cost-effectiveness analysis of initial treatment with single-pill combination antihypertensive medications [PDF]
, 2023 Alexis Bryan +8 more
openalex +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Cost-Effectiveness of Active Surveillance Compared to Early Surgery of Small Papillary Thyroid Cancer: A Retrospective Study on a Korean Population [PDF]
, 2023 Han-Sang Baek +7 more
openalex +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source