Results 101 to 110 of about 4,711 (207)

Irregular visits in longitudinal studies: Comparing inverse intensity of visit weighting and imputation in a causal analysis of antidepressant therapeutic treatment

Canadian Journal of Statistics, EarlyView.
Abstract Irregular observation times are common in longitudinal observational studies and can affect causal inferences. We use data from electronic health records of Kaiser Permanente Washington patients in the United States who initiated an antidepressant medication between 2008 and 2018, with a confirming diagnosis of depression. We are interested in
Janie Coulombe, Erica E. M. Moodie, Susan M. Shortreed   +2 more
wiley   +1 more source

Counterfactual Diffusion Models Provide Interpretable Explanations of Artificial Intelligence Models in Pathology. [PDF]

Cancer Res
Žigutytė L, Lenz T, Han T, Reitsam NG, Foersch S, Hewitt KJ, Jesinghaus M, Carrero ZI, Unger M, Meneghetti AR, Lurje G, Lurje I, Herda S, Pein J, Uluk D, Schneider CV, Pearson AT, Truhn D, Kather JN.   +18 more
europepmc   +1 more source

Model selection for causal inference in missing exposure problems

Canadian Journal of Statistics, EarlyView.
Abstract In causal inference, properly selecting the propensity score (PS) model is an important topic and has been widely investigated in observational studies. However, there are very few studies investigating the model selection issue for causal inference when the exposure is missing at random (MAR). When the exposure variable contains missing data,
Yuliang Shi, Yeying Zhu, Joel A. Dubin
wiley   +1 more source

Integrating Anatomical Priors Into a Causal Diffusion Model. [PDF]

IEEE Trans Med Imaging
Li B, Peng W, Li M, Adeli E, Pohl KM.
europepmc   +1 more source

Time‐Dependent Bias and Prognostic Confounding in Exposure–Response Analysis of Targeted Therapies: Lessons from Sunitinib in Metastatic Renal Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Exposure–response (E–R) analyses of sunitinib in metastatic renal cell carcinoma (mRCC) have supported concentration‐guided dose escalation. However, such analyses may be biased when exposure metrics incorporate post‐baseline dose modifications, time‐varying apparent clearance, or baseline factors that influence both pharmacokinetics and clinical ...
Han Liu, Lena E. Friberg
wiley   +1 more source

The Challenges of Hyperparameter Tuning for Accurate Causal Effect Estimation. [PDF]

Mach Learn
Machlanski D, Samothrakis S, Clarke P.
europepmc   +1 more source

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai, Anton L V Avanceña, Juan P Cata, Jamie C. Barner, Sharon H. Giordano, Chanhyun Park, Hui Zhao, Kirk E. Evoy, John K. Lin, Jennifer C. Spencer, Mariana Chavez‐MacGregor, Kelly K. Hunt, Kerollos Nashat Wanis   +12 more
wiley   +1 more source

Cross-Model Explainability Consistency in Hepatitis C Stage Classification: A SHAP, LIME, and Counterfactual Analysis Across Five Machine Learning Architectures. [PDF]

Diagnostics (Basel)
Alalawi K.
europepmc   +1 more source

ESG Ratings and Firms' Engagement in Global Innovation Ecosystems: Implications for Green Innovation Capacity

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The increasing salience of climate change has intensified attention to the roe of ESG ratings in shaping firms' green innovation. We examine the link between ESG performance and green innovation, highlighting the role of participation in global innovation networks.
Miaomiao Tao, David Roubaud, Mingzhi Zhang, Qianli Ma   +3 more
wiley   +1 more source

Chaotic and complex dynamics expose the limits of counterfactual reasoning. [PDF]

Sci Rep
Aalaila Y, Großmann G, Mukherjee S, Wahl J, Vollmer S.   +4 more
europepmc   +1 more source