Results 91 to 100 of about 7,843 (292)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Enhancing the power of quality issues using superconducting magnetic storage devices–based dynamic voltage restorer–aided switched coupled inductor inverter with space vector pulse width modulation techniques

Measurement + Control, 2019
This paper emphasizes on proposing a dynamic voltage restorer–based superconducting magnetic storage devices have utilized to power quality issues. Dynamic voltage restorer can be used for different topologies of the inverter.
P Sivaperumal, Subranhsu Sekhar Dash, K Saravanan   +2 more
doaj   +1 more source

Multimodal Resonance in Strongly Coupled Inductor Arrays [PDF]

IEEE Transactions on Instrumentation and Measurement
Magnetic resonance coupling (MRC) is widely used for wireless power transfer (WPT) applications, but little work has explored how MRC phenomena could be exploited for sensing applications. This paper introduces, validates and evaluates the unique multi-resonant phenomena predicted by circuit theory for over-coupled inductive arrays, and presents eigen ...
Robert R. Hughes, Alexis Hernandez Arroyo, James Treisman, Anthony J. Mulholland   +3 more
openaire   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

A Novel Reversal Γ-Shape Coupled Inductor High-Step AC-AC Converter

Energies, 2018
This paper presents a novel reversal Γ-shape coupled inductor high-step AC-AC converter. This converter uses a reversal Γ-shape coupled inductor that consists of a two-winding coupled inductor for higher voltage gain.
Hongchen Liu, Xinsheng Zhang
doaj   +1 more source

Boost-based MPPT for the MTM PCDU of the Bepicolombo mission [PDF]

, 2008
BepiColombo is an ESA mission to Mercury to be launched in 2013. A better knowledge of the origin and evolution of the planet, of its structure and vestigial atmosphere, of its magnetosphere, and of the origin of its magnetic field are the main ...
Alou Cervera, Pedro, Cobos Márquez, José Antonio, García Suárez, Oscar, Lapeña, Emilio, M. de las Mulas, E., Nuevo, M.A. del, Oliver Ramírez, Jesús Angel, Rancaño, J., Rueda, P., Soto de Pecho, Andrés   +9 more
core  

An integrated inductor for parallel interleaved VSCs connected in a whiffletree configuration [PDF]

, 2015
The quality of voltage waveform of the parallel connected inverters can be improved by interleaving the carrier signals. However, an additional coupled inductors (CIs) are required to suppress the circulating current between the interleaved VSCs and ...
Bede, Lorand, Blaabjerg, Frede, Gohil, Ghanshyamsinh, Kerekes, Tamas, Teodorescu, Remus   +4 more
core   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A wide input-voltage range quasi-Z source boost DC-DC converter with high voltage-gain for fuel cell vehicles [PDF]

, 2018
A quasi-Z-source Boost DC-DC converter which uses a switched-capacitor is proposed for fuel cell vehicles. The topology can obtain a high voltage gain with a wide input-voltage range, and requires only a low voltage stress across each of the components ...
Fu, Chuanzhi, Sumner, Mark, Wang, Ping, Zhang, Yun   +3 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source