Results 71 to 80 of about 337,508 (258)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Dynamical coupled-channel approach to hadronic and electromagnetic production of kaon-hyperon on the proton

, 2006
A dynamical coupled-channel formalism for processes $\pi N \to KY$ and $\gamma N \to KY$ is presented which provides a comprehensive investigation of recent data on the $\gamma p \to K^+ \Lambda$ reaction.
A. Švarc, B. Juliá-Díaz, B. Juliá-Díaz, B. S. Zou, B. Saghai, B. Saghai, B. Saghai, B. Saghai, F. Tabakin, H. Lenske, M. L. Goldberger, P. Bydzovsky, R. Bradford, T. Mart, T. Mart, T.-S. H. Lee, T.-S. H. Lee   +16 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

14C(11B, 9Be)16N reaction mechanisms and potential of the 9Be + 16N interaction [PDF]

Ядерна фізика та енергетика, 2013
New experimental data for differential cross sections of the 14С(11B, 9Be)16N reaction were measured for the ground states of 9Be and 16N nuclei as well as for the excited states of 16N at the energy Elab.(11В) = 45 MeV.
S. Yu. Mezhevych, A. T. Rudchik, K. Rusek, E. I. Koshchy, S. Kliczewski, A. V. Mokhnach, A. A. Rudchik, S. B. Sakuta, R. Siudak, B. Czech, J. Choiński, A. Szczurek   +11 more
doaj  

Fusion excitation function measurement for 6Li+64Ni at near-barrier energies

EPJ Web of Conferences, 2015
Total fusion excitation function has been measured for the reaction of weakly bound 6Li projectile on medium mass 64Ni target at energies near the Coulomb barrier of the system.
Shaikh Md. Moin, Roy Subinit, Rajbanshi S., Pradhan M. K., Mukherjee A., Basu P., Pal S., Nanal V., Pillay R. G., Shrivastav A.   +9 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

7Li(15N,14C)8Be reaction and 13,14C + 8Be nuclei interactions

Ядерна фізика та енергетика, 2017
Angular distributions of the 7Li(15N,14C)8Be reaction were measured at the energy Elab(15N) = 81 MeV. The reaction data were analyzed within coupled-reaction-channels (CRC) method. The 7Li + 15N elastic and inelastic scattering and the more important one-
А. Т. Rudchik, А. А. Rudchik, L. M. Muravynets, K. W. Kemper, К. Rusek, E. І. Koshchy, E. Piasecki, A. Trczinska, Val. М. Pirnak, О. А. Ponkratenko, V. А. Plujko, I. Strojek, A. Stolarz, S. B. Sakuta, А. P. Ilyin, u. M. Stepanenko, . V. Uleshchenko, Yu. O. Shyrma   +17 more
doaj  

Elastic and inelastic scattering of 11B ions by 14C at 45 MeV [PDF]

Ядерна фізика та енергетика, 2012
New experimental data for differential cross sections of 14С(11B, 11B)14С inelastic scattering at the energy Elab.(11В) = 45 MeV for transitions of 11B nucleus to the excited states of 2,12 - 8,56 MeV were obtained.
S. Yu. Mezhevych, A. T. Rudchik, K. Rusek, E. I. Koshchiy, S. Kliczewski, V. M. Kir'yanchuk, A. A. Rudchik, S. B. Sakuta, R. Siudak, B. Czech, J. Choinski, A. Szczurek   +11 more
doaj  

Coupled-channels density-matrix approach to low-energy nuclear reaction dynamics

, 2010
Atomic nuclei are complex, quantum many-body systems whose structure manifests itself through intrinsic quantum states associated with different excitation modes or degrees of freedom.
Diaz-Torres, Alexis
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source