Results 51 to 60 of about 1,086,052 (297)
Derivation of a fourth-order Co-simulation method for linear systems
In this article, we present a detailed derivation of a fourth order co-simulation method. This method is implicit and based on Hermite extrapolation with two support points and their derivatives.
Andrés Acosta +3 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Numerical simulation of coupled problems [PDF]
The paper briefly describes one numerical model for the simulation of fluid-structure coupled problems. The presented model is primarily intended to simulate the fluid-structure dynamic interaction in seismic conditions of civil engineering structures which are in direct contactwith fluid and which can often be encountered in engineering practice, for ...
Nikolić, Marina +2 more
openaire +4 more sources
Emergency surfacing acts as the final line of defense in preserving the operational viability of submarines, playing a crucial role in their safety. To investigate the dynamic characteristics of submarine emergency surfacing, utilizing whole moving mesh ...
Jiabao Chen +4 more
doaj +1 more source
This paper presents a multi-physics analysis coupling the electrical and thermal properties of a power module. As power modules have multi-physical behaviors, it is important to simulate their multi-physical characteristics.
Jangmuk Lim +6 more
doaj +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Impact of Non-Gaussian Winds on Blade Loading and Fatigue of Floating Offshore Wind Turbines
This study introduces a novel methodology for estimating loading and fatigue damage in the blades of wind turbines, emphasizing non-Gaussian wind conditions’ impact.
Shu Dai, Bert Sweetman, Shanran Tang
doaj +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Coupled Hydraulic Fracture and Proppant Transport Simulation
This paper focuses on the study of proppant transport mechanisms in fractures during frac-packing operation. A multi-module, numerical proppant, reservoir and geomechanics simulator has been developed, which improves the current numerical modeling ...
Morteza Roostaei +3 more
doaj +1 more source
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source

