Results 51 to 60 of about 4,152,141 (291)
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Multiphysics models for friction stir welding simulation [PDF]
, 2013 Purpose: The Friction Stir Welding (FSW) process comprises of several highly coupled (and non-linear) physical phenomena: large plastic deformation, material flow transportation, mechanical stirring of the tool, tool-workpiece surface interaction ...
Li, Hongjun +2 more
core +3 more sources
Multiway synchronization verified with coupled simulation
, 2006 We consider the problem of implementing multiway synchronization in a distributed environment providing only binary asynchronous communication. Our implementation strategy is formulated as a transformation on transition systems and we give a distributed algorithm for multiway synchronization. Correctness assertions and proofs are based on a new method:
Parrow, Joachim, Sjödin, Peter
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Multiscale simulation of coupled length-scales via meshless method and molecular dynamics
, 2009 A novel numerical approach employing a meshless technique with molecular dynamics is proposed for coupled length-scale simulations spanning continuum to atomistic regions.
Li, Hua +3 more
core +1 more source
Analysis and Testing of Straw Collector Crushing Mechanism Based on DEM-MBD Coupled Simulation
AgricultureTo address the low efficiency of corn straw collection, this study aims to optimize the design of the straw shredding mechanism of corn straw harvesters.
Jie Yang +6 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Development of a hydraulic model with integrated simulation of pipe and river networks
LHB Hydroscience JournalWith the rapid expansion of urbanisation, coupled simulation of stormwater pipe networks and river networks has become crucial for urban flood control and drainage planning. Traditional hydraulic models often employ separate numerical frameworks for pipe
Mingyan Wang +5 more
doaj +1 more source
Framework for coupled simulation of electrodialysis processes
, 2021 Zugl.: Dissertation, RWTH Aachen University, 2020.
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source