Results 61 to 70 of about 1,086,052 (297)

Analysis of Breaking and Separating Characteristics of Potato–Soil Aggregates Based on the New Type of Swing Separation Sieve

open access: yesAgronomy
In response to the significant challenge posed by the trade-off between the efficiency of separating potato soil and minimizing potato peel damage in the 4SW-170 potato excavator, this study focused on enhancing the design of the swing separation sieve ...
Shengshi Xie   +3 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Simulation and Optimization Experiment of Seven-Link Planting Mechanism Based on Discrete Element Method and Multibody Dynamics (DEM–MBD) Coupling

open access: yesAgriEngineering
To address issues in traditional vegetable transplanter planting mechanisms such as poor hole-forming quality and low seedling uprightness, a seven-bar linkage planting mechanism with posture compensation of seedling entering soil was designed.
Zhichao Cui   +12 more
doaj   +1 more source

ToPoliNano: Nano-magnet Logic Circuits Design and Simulation [PDF]

open access: yes, 2013
Among the emerging technologies Field-Coupled devices like Quantum dot Cellular Automata are particularly interesting. Of all the practical implementations of this principle NanoMagnet Logic shows many important features, such as a very low power ...
Frache, Stefano   +3 more
core  

Understanding analog quantum simulation dynamics in coupled ion-trap qubits

open access: yes, 2016
We study numerically a disordered transverse-field Ising Hamiltonian with long-range couplings. This model was recently investigated experimentally in a trapped-ion quantum simulator and was found to exhibit features of many-body localization at strong ...
Sarma, S. Das, Wu, Yang-Le
core   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Research on Dynamic Coupled Characteristics of A Tracked Vehicle Gearbox [PDF]

open access: yesInternational Journal of Computational Intelligence Systems, 2011
A tracked vehicle gearbox is divided into two subsystems-housing and gear train. Dynamic behaviors of the two subsystems are coupled practically. And the coupled characteristics describe the integrative dynamic behaviors of gearbox. This study proposes a
Hui Liu, Changle Xiang, Shengping Fu
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Design and Experiment of Air-Suction Roller-Type Minituber Seed-Metering Device Based on CFD-DEM

open access: yesAgriculture
Aiming at the problems of the high multiple- and missed-seeding index and low operation efficiency of current mechanical potato seed-meters in minituber sowing, this study designed an air-suction roller-type minituber seed-metering device for minitubers (
Jicheng Li   +6 more
doaj   +1 more source

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