Results 81 to 90 of about 4,152,141 (291)
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Shape Optimization Using the Aero-structural Coupled Adjoint Approach for Viscous Flows [PDF]
The aero-structural coupled adjoint approach here is an efficient approach to compute the gradients of the aerodynamic coefficients obtained from coupled fluid-structure simulations.
Brezillon, Joel, Abu-Zurayk, Mohammad
core
A Coupled Model of Acid Transport, Gel Cleanup, and Fracture Propagation in Prepad Acid Fracturing
In conventional hydraulic fracturing of low-permeability sandstone reservoirs, polymer-gel leak-off creates low-permeability filter cakes that impair productivity. This study proposes a prepad acid fracturing technique using a fluoroboric acid (HBF4) pre-
Weiyou Zhang +3 more
doaj +1 more source
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
GillespieSSA: Implementing the Gillespie Stochastic Simulation Algorithm in R [PDF]
The deterministic dynamics of populations in continuous time are traditionally described using coupled, first-order ordinary differential equations. While this approach is accurate for large systems, it is often inadequate for small systems where key ...
Mario Pineda-Krch
core
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
To systematically reveal the mechanism and parameter optimization path of staged hydraulic cavity creation technology in gas drainage from low-permeability coal seams, a coal damage-stress-seepage coupling model was established.
Tao Yu
doaj +1 more source
AETHER: A simulation platform for inductively coupled plasma
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Emre Turkoz, Murat Celik
openaire +4 more sources
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi +9 more
wiley +1 more source
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source

