Results 191 to 200 of about 350,390 (302)

Lost and Found: Is Olfactory Recovery More Promising After COVID‐19 Than Other Causes, Even 2 Years Later?

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory dysfunction is a hallmark feature of COVID‐19, yet the potential for recovery with long‐standing COVID‐19‐related smell loss (CRSL) remains uncertain, particularly when treatment is initiated years later. This study evaluated olfactory outcomes in patients with CRSL compared with non‐COVID‐19‐related smell loss (non‐CRSL),
John W. Hunsicker, Mabel Berg, Nicolaus Knight, Jessica W. Grayson, Bradford A. Woodworth, Justin H. Turner, Do‐Yeon Cho   +6 more
wiley   +1 more source

Old and new antirheumatic drugs for the treatment of COVID-19

Joint Bone Spine, 2020
Benucci, Maurizio, Damiani, Arianna, Infantino, Maria, Manfredi, Mariangela, Quartuccio, Luca   +4 more
openaire   +2 more sources

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

Animal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma, Masaki Watanabe, Nobuya Sasaki   +2 more
wiley   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Risk assessment for cardiovascular adverse drug events in the ICU: Case study on COVID-19 patients. [PDF]

PLoS One
Freitas NL, Oliveira RD, Santos AKDS, Cunha-Filho M, Medeiros-Souza P.   +4 more
europepmc   +1 more source

Electrical Impedance Myography Detects Disease Progression over 12 to 24 Months in Facioscapulohumeral Muscular Dystrophy

Annals of Neurology, EarlyView.
Objective Targeted therapies for facioscapulohumeral muscular dystrophy (FSHD) are progressing through clinical trials. Electrical impedance myography (EIM) provides a noninvasive biomarker of muscle composition that may be valuable especially in early phase trials. This study evaluated EIM data from a multicenter FSHD cohort over 24 months.
Karlien Mul, Michael P. McDermott, Russell J. Butterfield, Bakri Elsheikh, Kate Eichinger, Nicholas E. Johnson, Doris G. Leung, Samantha LoRusso, Leann Lewis, William B. Martens, Perry B. Shieh, Leo H. Wang, Michaela Walker, Rabi Tawil, Jeffrey M. Statland, ReSolve Investigators of the FSHD‐CTRN   +15 more
wiley   +1 more source

Commentary: No-test medication abortion: A sample protocol for increasing access during a pandemic and beyond. [PDF]

, 2020
Atrio, Jessica M, Coplon, Leah, Creinin, Mitchell D, Dean, Gillian, Gold, Marji, Grossman, Daniel, Mark, Alice, Perritt, Jamila, Raymond, Elizabeth G, Taylor, DeShawn, Upadhyay, Ushma D   +10 more
core   +1 more source

Experiences of People Who Use Drugs in Rural Southeastern Ohio During the COVID-19 Pandemic: Harm Reduction, Substance Use Treatment, and Trusted Information Sources. [PDF]

J Stud Alcohol Drugs
Enderle MN, Piscalko HM, Limarzi-Klyn L, Colston DC, Sibley AL, Estadt AT, Go VF, Miller WC.   +7 more
europepmc   +1 more source

Remdesivir as a possible therapeutic option for the COVID-19 [PDF]

, 2020
Al-Homoud, Ali H., Al-Tawfiq, Jaffar A., Memish, Ziad A.   +2 more
core   +1 more source

Prospective Study of Treatment with Ensitrelvir for COVID-19 in Patients Undergoing Hemodialysis (PROTECT-HD). [PDF]

Infect Dis Ther
Kitamura M, Takazono T, Hosogaya N, Morimoto S, Kinoshita M, Hamada E, Shimizu R, Miyazawa S, Tanaka S, Nishino T, Mukae H.   +10 more
europepmc   +1 more source