Results 71 to 80 of about 231,281 (308)

Potential therapeutic drug candidates against SARS-CoV-2 (COVID‐19) through molecular docking: A review [PDF]

open access: yesHealth Science Monitor, 2022
The severe acute respiratory syndrome coronavirus 2 (known as COVID-19), initially appeared in the Wuhan city of China in December 2019, has become a current medical issue around the world.
Aynaz Nourani   +2 more
doaj  

Repurposed pharmacological agents for the potential treatment of COVID-19: a literature review

open access: yesRespiratory Research, 2021
Background The COVID-19 pandemic has affected the world extraordinarily. This disease has a potential to cause a significantly severe course of disease leading to respiratory complications, multiple organ failure and possibly death.
Alina Kröker, Madara Tirzīte
doaj   +1 more source

Prevention and treatment of ventilator-associated pneumonia in COVID-19

open access: yesFrontiers in Pharmacology, 2022
Ventilator-associated pneumonia (VAP) is the most common acquired infection in the intensive care unit. Recent studies showed that the critical COVID-19 patients with invasive mechanical ventilation have a high risk of developing VAP, which result in a ...
Jiayi Deng   +4 more
doaj   +1 more source

Remdesivir Alone or in Combination with Monoclonal Antibodies as an Early Treatment to Prevent Severe COVID-19 in Patients with Mild/Moderate Disease at High Risk of Progression: A Single Centre, Real-Life Study

open access: yes, 2023
Early treatment with antivirals against SARS-CoV-2 infection can prevent the onset of severe COVID-19 in fragile and immunocompromised patients. In this real-life, prospective, observational study, we evaluated efficacy and safety of a 3-day early ...
Alessia Sardanelli   +9 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Tackling Immune Pathogenesis of COVID-19 through Molecular Pharmaceutics

open access: yesPharmaceutics, 2021
An increasing number of clinical studies worldwide are investigating the repurposing of antiviral, immune-modulatory, and anti-inflammatory agents to face the coronavirus disease-19 (COVID-19) pandemic.
Matteo Puccetti   +3 more
doaj   +1 more source

Drug treatment for Covid-19 - three years later

open access: yesInfectious Diseases Now, 2023
There has been a profusion of trials for SARS CoV2 drugs. A review dating from May 2020 listed 115 medicines, most of which previously existed, having been investigated since the onset of the pandemic. Over an exceedingly short lapse of time, the perspective of the arrival of a new antiviral treatment specifically targeting COVID-19 appeared highly ...
openaire   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Alcohol and other drug treatment services in Australia annual report.

open access: yes, 2021
Alcohol and other drug (AOD) treatment agencies across Australia provide a range of services and support to people receiving treatment for their own drug use, as well as for their families and friends.

core  

Potential Therapeutic Options for COVID-19: Current Status, Challenges, and Future Perspectives

open access: yesFrontiers in Pharmacology, 2020
The COVID-19 pandemic represents an unprecedented challenge for the researchers to offer safe, tolerable, and effective treatment strategies for its causative agent known as SARS-CoV-2.
Chandan Sarkar   +9 more
doaj   +1 more source

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