Results 61 to 70 of about 13,629 (283)
Classification of Cowpox Viruses into Several Distinct Clades and Identification of a Novel Lineage
Viruses, 2017 Cowpox virus (CPXV) was considered as uniform species within the genus Orthopoxvirus (OPV). Previous phylogenetic analysis indicated that CPXV is polyphyletic and isolates may cluster into different clades with two of these clades showing genetic ...
A. Franke +8 more
semanticscholar +1 more source
The myth of the medical breakthrough: Smallpox, vaccination, and Jenner reconsidered [PDF]
, 1998 A discussion of the particulars leading to the eradication of smallpox is pertinent to both investigators and the public as the clamor for more “breakthroughs” intensifies.
Gross, Cary P., Sepkowitz, Kent A.
core +1 more source
Animal Models and Experimental Medicine, EarlyView.We successfully constructed CAST/EiJ mice models infected with low‐dose vaccinia virus (VACV‐L), high‐dose VACV (VACV‐H), and mpox virus (MPXV), demonstrating that VACV‐L and MPXV infections induced splenomegaly in mice, and VACV‐H infection caused mortality in mice.
Yongzhi Hou +9 more
wiley +1 more source
PLoS ONE, 2015 Cowpox virus (CPXV) causes most zoonotic orthopoxvirus (OPV) infections in Europe and Northern as well as Central Asia. The virus has the broadest host range of OPV and is transmitted to humans from rodents and other wild or domestic animals.
Joerg Doellinger +2 more
openalex +3 more sources
Effects of nasal or pulmonary delivered treatments with an adenovirus vectored interferon (mDEF201) on respiratory and systemic infections in mice caused by cowpox and vaccinia viruses. [PDF]
PLoS ONE, 2013 An adenovirus 5 vector encoding for mouse interferon alpha, subtype 5 (mDEF201) was evaluated for efficacy against lethal cowpox (Brighton strain) and vaccinia (WR strain) virus respiratory and systemic infections in mice.
Donald F Smee +4 more
doaj +1 more source
Increasing protectivity of the smallpox vaccine
Медицинская иммунология, 2022 At the present time, vast majority of human population lacks immunity against orthopoxvirus infections caused by variola (smallpox), monkeypox, cowpox, or buffalopox viruses.
S. N. Shchelkunov +4 more
doaj +1 more source
Promising Prodiginins Biological Activities
Chemistry &Biodiversity, EarlyView.ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto +6 more
wiley +1 more source
What a Difference a Gene Makes: Identification of Virulence Factors of Cowpox Virus
Journal of Virology, 2019 With the cessation of vaccination against smallpox and its assumed cross-protectivity against other OPV infections, waning immunity could open up new niches for related poxviruses.
A. Tamošiūnaitė +11 more
semanticscholar +1 more source
Unusual presentations of feline cowpox [PDF]
Veterinary Record, 2016 WE would like to share with colleagues a significant increase in the number and severity of feline cowpox (FPxV) cases positively diagnosed in the UK in recent weeks. At a recent meeting of the International Society for Companion Animal Infectious Diseases, it was noted by several clinicians, as well as the present authors, that the severity of ...
O'Halloran, Conor +7 more
openaire +3 more sources
Flow Cytometry and T-Cell Response Monitoring after Smallpox Vaccination
Emerging Infectious Diseases, 2003 Orthopoxvirus zoonosis or smallpox as result of bioterrorism or biological warfare represents a risk for epidemic spread. By monitoring T-cell responses by flow cytometry, we observed a recall response after recent vaccination against smallpox.
Fabrizio Poccia +8 more
doaj +1 more source