Cowpox Virus: A New and Armed Oncolytic Poxvirus [PDF]
Molecular Therapy: Oncolytics, 2017 Oncolytic virus therapy has recently been recognized as a promising new therapeutic approach for cancer treatment. In this study, we are proposing for the first time to evaluate the in vitro and in vivo oncolytic capacities of the Cowpox virus (CPXV). To
Marine Ricordel +11 more
doaj +9 more sources
Cowpox virus: What’s in a Name? [PDF]
Viruses, 2017 Traditionally, virus taxonomy relied on phenotypic properties; however, a sequence-based virus taxonomy has become essential since the recent requirement of a species to exhibit monophyly.
Matthew R. Mauldin +6 more
doaj +5 more sources
Chasing Jenner's vaccine: revisiting cowpox virus classification. [PDF]
PLoS ONE, 2011 Cowpox virus (CPXV) is described as the source of the first vaccine used to prevent the onset and spread of an infectious disease. It is one of the earliest described members of the genus Orthopoxvirus, which includes the viruses that cause smallpox and ...
Darin S Carroll +16 more
doaj +6 more sources
Genomic Sequencing and Phylogenomics of Cowpox Virus [PDF]
Viruses, 2022 Cowpox virus (CPXV; genus Orthopoxvirus; family Poxviridae) is the causative agent of cowpox, a self-limiting zoonotic infection. CPXV is endemic in Eurasia, and human CPXV infections are associated with exposure to infected animals. In the Fennoscandian
Diana Diaz-Cánova +5 more
doaj +5 more sources
Atypical Cowpox Virus Infection in Smallpox-Vaccinated Patient, France [PDF]
Emerging Infectious Diseases, 2019 We report a case of atypical cowpox virus infection in France in 2016. The patient sought care for thoracic lesions after injury from the sharp end of a metallic guardrail previously stored in the ground.
Julien Andreani +8 more
doaj +4 more sources
Genomic Sequencing and Analysis of a Novel Human Cowpox Virus With Mosaic Sequences From North America and Old World Orthopoxvirus [PDF]
Frontiers in Microbiology, 2022 Orthopoxviruses (OPXVs) not only infect their natural hosts, but some OPXVs can also cause disease in humans. Previously, we partially characterized an OPXV isolated from an 18-year-old male living in Northern Norway.
Diana Diaz-Cánova +4 more
doaj +2 more sources
Orthopoxvirus DNA in Eurasian Lynx, Sweden [PDF]
Emerging Infectious Diseases, 2011 Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe.
Morten Tryland +5 more
doaj +6 more sources
Seasonal recurrence of cowpox virus outbreaks in captive cheetahs (Acinonyx jubatus). [PDF]
PLoS ONE, 2017 Cowpox virus infections in captive cheetahs (Acinonyx jubatus) with high morbidity and mortality have already been reported in the UK and Russia in the 1970s. However, most of the reported cases have been singular events.
Julia Stagegaard +6 more
doaj +2 more sources
Determination of the minimal level of neutralizing antibodies elicited following vaccination able to protect rabbits against virulent cowpox virus [PDF]
Frontiers in ImmunologyBackgroundSerological assessment of antibody levels is a crucial measure of immunity in vaccinated animals. Establishing the level of antibodies considered protective is essential for vaccine standardization and evaluation of efficacy.
Muratbay Mambetaliyev +4 more
doaj +2 more sources
Cowpox Virus Transmission from Pet Rats to Humans, France [PDF]
Emerging Infectious Diseases, 2009 In early 2009, four human cases of cowpox virus cutaneous infection in northern France, resulting from direct contact with infected pet rats (Rattus norvegicus), were studied.
Laetitia Ninove +9 more
doaj +2 more sources