Cowpox Virus: A New and Armed Oncolytic Poxvirus [PDF]
Molecular Therapy: Oncolytics, 2017 Oncolytic virus therapy has recently been recognized as a promising new therapeutic approach for cancer treatment. In this study, we are proposing for the first time to evaluate the in vitro and in vivo oncolytic capacities of the Cowpox virus (CPXV). To
Marine Ricordel +11 more
doaj +9 more sources
Genomic expression libraries for the identification of cross-reactive orthopoxvirus antigens. [PDF]
PLoS ONE, 2011 Increasing numbers of human cowpox virus infections that are being observed and that particularly affect young non-vaccinated persons have renewed interest in this zoonotic disease.
Lilija Miller +4 more
doaj +15 more sources
Orthopoxvirus DNA in Eurasian Lynx, Sweden [PDF]
Emerging Infectious Diseases, 2011 Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe.
Morten Tryland +5 more
doaj +6 more sources
Cowpox with Severe Generalized Eruption, Finland [PDF]
Emerging Infectious Diseases, 2003 Cowpox with a severe, generalized eruption was diagnosed in an atopic 4-year-old girl by electron microscopy, virus isolation, polymerase chain reaction, and immunoglobulin (Ig) M and low-avidity IgG antibodies.
Paula M. Pelkonen +7 more
doaj +4 more sources
How cowpox virus turns back cell defenses. [PDF]
PLoS Biology, 2012 Viruses follow a well-choreographed battle plan to mount an infection. First, they invade cells, then stage a takeover of its genetic and protein replication machinery. Once the virus assumes control, it forces the cell to create thousands of copies of the virus, which usually ends up killing the cell.
Caitlin Sedwick
doaj +5 more sources
A negative feedback modulator of antigen processing evolved from a frameshift in the cowpox virus genome. [PDF]
PLoS Pathogens, 2014 Coevolution of viruses and their hosts represents a dynamic molecular battle between the immune system and viral factors that mediate immune evasion. After the abandonment of smallpox vaccination, cowpox virus infections are an emerging zoonotic health ...
Jiacheng Lin +6 more
doaj +2 more sources
Antiviral activity of the EB peptide against zoonotic poxviruses [PDF]
Virology Journal, 2012 Background The EB peptide is a 20-mer that was previously shown to have broad spectrum in vitro activity against several unrelated viruses, including highly pathogenic avian influenza, herpes simplex virus type I, and vaccinia, the prototypic ...
Altmann Sharon E +3 more
doaj +5 more sources
Experimental Cowpox Virus (CPXV) Infections of Bank Voles: Exceptional Clinical Resistance and Variable Reservoir Competence [PDF]
Viruses, 2017 Cowpox virus (CPXV) is a zoonotic virus and endemic in wild rodent populations in Eurasia. Serological surveys in Europe have reported high prevalence in different vole and mouse species.
Annika Franke +6 more
doaj +2 more sources
Concomitant Human Infections with 2 Cowpox Virus Strains in Related Cases, France, 2011 [PDF]
Emerging Infectious Diseases, 2013 We investigated 4 related human cases of cowpox virus infection reported in France during 2011. Three patients were infected by the same strain, probably transmitted by imported pet rats, and the fourth patient was infected by another strain.
Corinne Ducournau +11 more
doaj +2 more sources
Rat-to-Human Transmission of Cowpox Infection [PDF]
Emerging Infectious Diseases, 2002 We isolated Cowpox virus (CPXV) from the ulcerative eyelid lesions of a 14-year-old girl, who had cared for a clinically ill wild rat that later died. CPXV isolated from the rat (Rattus norvegicus) showed complete homology with the girl’s virus. Our case
Tom F.W. Wolfs +3 more
doaj +3 more sources