Results 71 to 80 of about 9,882 (215)
Cowpox Virus Transmission from Rats to Monkeys, the Netherlands
Emerging Infectious Diseases, 2006 We report an outbreak of cowpox virus among monkeys at a sanctuary for exotic animals. Serologic analysis and polymerase chain reaction were performed on blood and swab samples from different rodent species trapped at the sanctuary during the outbreak ...
Byron E.E. Martina +7 more
doaj +1 more source
Emergence of cowpox: study of the virulence of clinical strains and evaluation of antivirals. [PDF]
PLoS ONE, 2013 The last years, cowpox infections are being increasingly reported through Eurasia. Cowpox viruses (CPXVs) have been reported to have different genotypes and may be subdivided in at least five genetically distinct monophyletic clusters. However, little is
Sophie Duraffour +7 more
doaj +1 more source
Structural conservation and functional diversity of the Poxvirus Immune Evasion (PIE) domain superfamily [PDF]
, 2015 Poxviruses encode a broad array of proteins that serve to undermine host immune defenses. Structural analysis of four of these seemingly unrelated proteins revealed the recurrent use of a conserved beta-sandwich fold that has not been observed in any ...
Alcami +40 more
core +3 more sources
Advanced Science, EarlyView.Tumor vascular remodeling is discussed from a chemokine‐centered perspective. This review summarizes the bidirectional, temporal, and tissue‐specific roles of CXC chemokines in regulating vascular function and immune accessibility. A functional vascular normalization score is introduced as a conceptual framework to integrate dynamic vascular and immune
Hongdan Chen +7 more
wiley +1 more source
The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations
Acta Paediatrica, EarlyView.ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley +1 more source
Incongruencies in Vaccinia Virus Phylogenetic Trees
Computation, 2014 Over the years, as more complete poxvirus genomes have been sequenced, phylogenetic studies of these viruses have become more prevalent. In general, the results show similar relationships between the poxvirus species; however, some inconsistencies are ...
Chad Smithson +3 more
doaj +1 more source
Variola virus in a 300-year-old Siberian mummy. [PDF]
, 2012 International audienceNo abstract ...
Alekseev, Anatoly N +14 more
core +3 more sources
Treatment of Vaccinia and Cowpox Virus Infections in Mice with CMX001 and ST-246
Viruses, 2010 Although a large number of compounds have been identified with antiviral activity against orthopoxviruses in tissue culture systems, it is highly preferred that these compounds have activity in vivo before they can be seriously considered for further ...
Earl R. Kern, Debra C. Quenelle
doaj +1 more source
Mpox and the Ethics of Outbreak Management: Lessons for Future Public Health Crises
Developing World Bioethics, EarlyView.ABSTRACT Mpox, first identified in captive monkeys in 1958 and recognized in humans by 1970 in the Democratic Republic of Congo, was historically confined to sporadic zoonotic outbreaks in Central and West Africa. These outbreaks, often driven by rodent‐to‐human transmission in resource‐limited settings, reflect persistent systemic health disparities ...
Adetayo E. Obasa +3 more
wiley +1 more source