Results 161 to 170 of about 26,709,678 (285)

Solubility enhancement of cox-2 inhibitors using various solvent systems

AAPS PharmSciTech, 2003
N. Seedher, Sonu Bhatia
semanticscholar   +1 more source

Crosstalk Between CTSB+ Glioblastoma Cells and S100A10+ Macrophages: A Self‐Reinforcing Circuit Promotes Immune Evasion and Limits Response to Immunotherapy

Advanced Science, EarlyView.
In glioblastoma, M2‐polarized macrophages secrete IL‐6, which activates STAT3 signaling in tumor cells to upregulate CTSB. Tumor‐derived CTSB binds the C‐terminus of macrophage S100A10, reinforcing M2 polarization and further IL‐6 secretion, thereby establishing a feedforward IL‐6/STAT3/CTSB/S100A10 loop. This cascade drives tumor growth, invasion, and
Hao Zhang, Nan Zhang, Xisong Liang, Jie Wen, Ziyu Dai, Wantao Wu, Shuyu Li, Songshan Feng, Zaoqu Liu, Zhiwei Xia, Peng Luo, Quan Cheng   +11 more
wiley   +1 more source

The COX-2 inhibitors: a reasoned review of the data

Swiss Medical Weekly, 2005
L Simon
doaj   +1 more source

Design and synthesis of isoxazolidine core-based selective COX-2 inhibitors: <i>in vitro</i> inhibitor activity and <i>in silico</i> modeling. [PDF]

RSC Adv
Al-Adhreai A, ALSaeedy M, Nuha D, Trawally M, Ullah R, Ali SM, M Alaizeri Z, Güner S, Gatasheh MK.   +8 more
europepmc   +1 more source

Age related effects of selective and non-selective COX-2 inhibitors on bone healing. [PDF]

J Clin Orthop Trauma, 2022
Kigera JWM, Gichangi PB, Abdelmalek AKM, Ogeng'o JA.   +3 more
europepmc   +1 more source

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

Advanced Science, EarlyView.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan, Xuan Liu, Qian‐Fang Meng, Lei Cao, Rongrong Li, Yangtao Xu, Jing Zhang, Chenchen Zhao, Lang Rao, Chen Yu   +9 more
wiley   +1 more source

A New Survey about Dual-Acting PARP/COX-2 Inhibitors as Cancer Chemopreventive Agents. [PDF]

Iran J Pharm Res
Ismail Mahboubi Rabbani M, Aliabadi A, Bayat L, Jafari M, Bagheri AH, Shateri S, Hakimimofrad R, Bayanati M, Zarghi A, Zarghi A.   +9 more
europepmc   +1 more source

Homespun quilt, by Elvira Pamela Mills Cox

Image of Homespun quilt created circa 1860-1880 by Elvira Pamela Mills Cox. Also includes questionnaires describing the quilt completed by Nancy Cox Mackay as part of the Utah Quilt Guild\u27s documentation days held from 1988-1994.
Cox, Elvira Pamela Mills
core  

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

Advanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang, Wenhui Xie, Lei Yang, Zhengrong Wang, Yi Huang, Peng Huang, Yuan Liu, Jun Hu   +7 more
wiley   +1 more source

Design and Synthesis of Thiadiazole Derivatives as Dual EGFR/COX‑2 Inhibitors with Anticancer and Anti-inflammatory Activities. [PDF]

ACS Omega
Hidir A, Osmaniye D, Sağlik Özkan BN, Levent S, Kaplancikli ZA, Özkay Y.   +5 more
europepmc   +1 more source