Results 51 to 60 of about 1,415,363 (344)

Expected Survival in the Cox Model

open access: yesScandinavian Journal of Statistics, 1997
The survival in a group of patients is calculated using a Kaplan–Meier curve and the hypothesis that the survival can be predicted by a specified Cox hazard is studied. This Cox hazard is obtained from a previous study of similar patients. A simple test of the hypothesis is constructed by comparing a suitable average of the individual predicted ...
openaire   +3 more sources

Oracle inequalities for the lasso in the Cox model

open access: yesThe Annals of Statistics, 2013
We study the absolute penalized maximum partial likelihood estimator in sparse, high-dimensional Cox proportional hazards regression models where the number of time-dependent covariates can be larger than the sample size. We establish oracle inequalities based on natural extensions of the compatibility and cone invertibility factors of the Hessian ...
Huang, Jian   +4 more
openaire   +6 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Wiener Chaos and the Cox-Ingersoll-Ross model [PDF]

open access: yes, 2003
In this we paper we recast the Cox--Ingersoll--Ross model of interest rates into the chaotic representation recently introduced by Hughston and Rafailidis.
Grasselli, M. R., Hurd, T. R.
core   +1 more source

Structured estimation for the nonparametric Cox model

open access: yesElectronic Journal of Statistics, 2015
To better understand the interplay of censoring and sparsity we develop finite sample properties of nonparametric Cox proportional hazard's model. Due to high impact of sequencing data, carrying genetic information of each individual, we work with over-parametrized problem and propose general class of group penalties suitable for sparse structured ...
Bradic, Jelena, Song, Rui
openaire   +5 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Particle Swarm Optimization for Penalize cox models in long-term prediction of breast cancer data

open access: yesIraqi Journal for Computer Science and Mathematics, 2023
The particle swarm optimization algorithm (PSO) was applied to penalize the Cox model for predicting long-term outcomes of breast cancer patients.
Ehab Abbas, Basad Al-Sarray
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Assessment of Survival Rate and Affected Factor in Referred Patients with Postoperative Gastric Cancer in Be\'sat Hospital of Hamadan Province

open access: yesپزشکی بالینی ابن سینا, 2015
Introduction & Objective: Gastric cancer is the forth common cancer and second cause of death. Surgery is the primary treatment of gastric cancer and chemotherapy and radiotherapy is used as supplementary treatments.
Mohammadreza Javadi   +4 more
doaj  

From Transience to Recurrence for Cox–Ingersoll–Ross Model When b < 0

open access: yesMathematics, 2023
We consider the Cox–Ingersoll–Ross (CIR) model in time-dependent domains, that is, the CIR process in time-dependent domains reflected at the time-dependent boundary.
Mingli Zhang, Gaofeng Zong
doaj   +1 more source

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