Results 51 to 60 of about 1,478,952 (298)
پزشکی بالینی ابن سینا, 2015 Introduction & Objective: Gastric cancer is the forth common cancer and second cause of death. Surgery is the primary treatment of gastric cancer and chemotherapy and radiotherapy is used as supplementary treatments.
Mohammadreza Javadi +4 more
doaj
joineR: Joint modelling of repeated measurements and time-to-event data [PDF]
, 2012 The joineR package implements methods for analysing data from longitudinal studies in which the response from each subject consists of a time-sequence of repeated measurements and a possibly censored time-toevent outcome.
Diggle, Peter +5 more
core
Asymptotic theory for the Cox model with missing time-dependent covariate
, 2006 The relationship between a time-dependent covariate and survival times is usually evaluated via the Cox model. Time-dependent covariates are generally available as longitudinal data collected regularly during the course of the study.
Dupuy, Jean-François +2 more
core +2 more sources
Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney [PDF]
, 2015 BACKGROUND: The role of cyclooxygenase(COX)-1 and COX-2 in the saluretic and renin-angiotensin responses to loop diuretics in the cat is unknown. We propose in vivo characterisation of isoform roles in a furosemide model by administering non-steroidal ...
A Hayes +42 more
core +3 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Testing and interpreting assumptions of COX regression analysis
Cancer Research, Statistics, and Treatment, 2019 The COX regression analysis is like any statistical test that is based on multiple assumptions. This is a guide for how to test the assumptions and how to interpret the results.
Sampada Dessai, Vijay Patil
doaj +1 more source
Particle Swarm Optimization for Penalize cox models in long-term prediction of breast cancer data
Iraqi Journal for Computer Science and Mathematics, 2023 The particle swarm optimization algorithm (PSO) was applied to penalize the Cox model for predicting long-term outcomes of breast cancer patients.
Ehab Abbas, Basad Al-Sarray
doaj +1 more source
Tree-augmented Cox proportional hazards models [PDF]
Biostatistics, 2005 We study a hybrid model that combines Cox proportional hazards regression with tree-structured modeling. The main idea is to use step functions, provided by a tree structure, to 'augment' Cox (1972) proportional hazards models. The proposed model not only provides a natural assessment of the adequacy of the Cox proportional hazards model but also ...
Su, Xiaogang, Tsai, Chih Ling
openaire +4 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source