Results 21 to 30 of about 30,146 (255)

Virus Infection Is an Instigator of Intestinal Dysbiosis Leading to Type 1 Diabetes

Frontiers in Immunology, 2021
In addition to genetic predisposition, environmental determinants contribute to a complex etiology leading to onset of type 1 diabetes (T1D). Multiple studies have established the gut as an important site for immune modulation that can directly impact ...
Zachary J. Morse, Marc S. Horwitz
doaj   +1 more source

Genomic epidemiology of coxsackievirus A16 in mainland of China, 2000–18

Virus Evolution, 2020
Hand, foot, and mouth disease (HFMD), which is a frequently reported and concerning disease worldwide, is a severe burden on societies globally, especially in the countries of East and Southeast Asia.
Zhenzhi Han, Yang Song, Jinbo Xiao, Lili Jiang, Wei Huang, Hai-yan Wei, Jie Li, H. Zeng, Qiu-li Yu, Jiameng Li, De-shan Yu, Yanjun Zhang, Chonghai Li, Z. Zhan, Yonglin Shi, Ying Xiong, Xianjun Wang, T. Ji, Qian Yang, Shuang-li Zhu, D. Yan, Wenbo Xu, Yong Zhang   +22 more
semanticscholar   +1 more source

Emerging Enteroviruses Causing Hand, Foot and Mouth Disease, China, 2010–2016

Emerging Infectious Diseases, 2018
Coxsackievirus A6 emerged as one of the predominant causative agents of hand, foot and mouth disease epidemics in many provinces of China in 2013 and 2015.
Yu Li, Zhaorui Chang, Peng Wu, Qiaohong Liao, Fengfeng Liu, Yaming Zheng, Li Luo, Yonghong Zhou, Qi Chen, Shuanbao Yu, Chun Guo, Zhenhua Chen, Lu Long, Shanlu Zhao, Bingyi Yang, Hongjie Yu, Benjamin J. Cowling   +16 more
doaj   +1 more source

Enteroviruses Manipulate the Unfolded Protein Response through Multifaceted Deregulation of the Ire1-Xbp1 Pathway

Viruses, 2022
Many viruses are known to trigger endoplasmic reticulum (ER) stress in host cells, which in turn can develop a protective unfolded protein response (UPR). Depending on the conditions, the UPR may lead to either cell survival or programmed cell death. One
Anna Shishova, Ilya Dyugay, Ksenia Fominykh, Victoria Baryshnikova, Alena Dereventsova, Yuriy Turchenko, Anna A. Slavokhotova, Yury Ivin, Sergey E. Dmitriev, Anatoly Gmyl   +9 more
doaj   +1 more source

The coxsackievirus and adenovirus receptor: virological and biological beauty

FEBS Letters, 2020
The coxsackievirus and adenovirus receptor (CAR) is an essential multifunctional cellular protein that is only beginning to be understood. CAR serves as a receptor for many adenoviruses, human group B coxsackieviruses, swine vesicular disease virus, and ...
K. Excoffon
semanticscholar   +1 more source

Pharmacological and Biological Antiviral Therapeutics for Cardiac Coxsackievirus Infections

Molecules, 2011
Subtype B coxsackieviruses (CVB) represent the most commonly identified infectious agents associated with acute and chronic myocarditis, with CVB3 being the most common variant.
Jens Kurreck, Wolfgang Poller, Henry Fechner, Anja Geisler, Sandra Pinkert   +4 more
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Direct and Indirect Effects on Viral Translation and RNA Replication Are Required for AUF1 Restriction of Enterovirus Infections in Human Cells

mBio, 2018
The cellular mRNA decay protein AUF1 acts as a restriction factor during infection by picornaviruses, including poliovirus, coxsackievirus, and human rhinovirus.
Wendy Ullmer, Bert L. Semler
doaj   +1 more source

Comparison of Monoclonal Gammopathies Linked to Poliovirus or Coxsackievirus vs. Other Infectious Pathogens

Cells, 2021
Chronic stimulation by infectious pathogens or self-antigen glucosylsphingosine (GlcSph) can lead to monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM).
Jean Harb, Nicolas Mennesson, Cassandra Lepetit, Maeva Fourny, Margaux Louvois, Adrien Bosseboeuf, Sophie Allain-Maillet, Olivier Decaux, Caroline Moreau, Anne Tallet, Eric Piver, Philippe Moreau, Valéry Salle, Edith Bigot-Corbel, Sylvie Hermouet   +14 more
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Coxsackievirus A16 [PDF]

Human Vaccines & Immunotherapeutics, 2013
Coxsackievirus 16 (CA16) is one of the major pathogens associated with hand, foot, and mouth disease (HFMD) in infants and young children. In recent years, CA16 and human enterovirus 71 (EV71) have often circulated alternatively or together in the Western Pacific region, which has become an important public health problem in this region. HFMD caused by
Qunying, Mao, Yiping, Wang, Xin, Yao, Lianlian, Bian, Xing, Wu, Miao, Xu, Zhenglun, Liang   +6 more
openaire   +2 more sources

Enterovirus Neutralizing Antibodies, Monocyte Toll Like Receptors Expression and Interleukin Profiles Are Similar Between Non-affected and Affected Siblings From Long-Term Discordant Type 1 Diabetes Multiplex-Sib Families: The Importance of HLA Background

Frontiers in Endocrinology, 2020
Enteroviruses are main candidates among environmental agents in the development of type 1 diabetes (T1D). However, the relationship between virus and the immune system response during T1D pathogenesis is heterogeneous. This is an interesting paradigm and
Carla Sanchez Bergamin, Elizabeth Pérez-Hurtado, Luanda Oliveira, Monica Gabbay, Valdecira Piveta, Célia Bittencourt, Denise Russo, Rita de Cássia Carmona, Maria Sato, Sergio A. Dib   +9 more
doaj   +1 more source