Heliyon, 2023 Objectives: This study was performed to investigate the effect of non-pharmaceutical interventions on hand, foot, and mouth disease in Hubei Province China during the coronavirus disease 2019 pandemic.
Kangping Zhou +4 more
doaj +1 more source
Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal. [PDF]
, 2013 Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the ...
Crawford, Sue E. +4 more
core +2 more sources
Coxsackie B2 Virus Infection Causing Multiorgan Failure and Cardiogenic Shock in a 42-Year-Old Man [PDF]
, 2019 Infections from coxsackie B2 viruses often cause viral myocarditis and, only rarely, multisystem organ impairment. We present the unusual case of a 42-year-old man in whom coxsackie B2 virus infection caused multiorgan infection, necessitating distal ...
Abdou, Mahmoud H. +2 more
core +1 more source
SUMO Modification Stabilizes Enterovirus 71 Polymerase 3D To Facilitate Viral Replication. [PDF]
, 2016 Accumulating evidence suggests that viruses hijack cellular proteins to circumvent the host immune system. Ubiquitination and SUMOylation are extensively studied posttranslational modifications (PTMs) that play critical roles in diverse biological ...
Gong, P +9 more
core +1 more source
Beyond self-eating: The control of nonautophagic functions and signaling pathways by autophagy-related proteins. [PDF]
, 2017 The identification of conserved autophagy-related proteins (ATGs) that mediate bulk degradation of cytosolic material laid the foundation for breakthroughs linking autophagy to a litany of physiological processes and disease conditions.
Cadwell, Ken, Debnath, Jayanta
core +1 more source
Angewandte Chemie, EarlyView.Deubiquitinases (DUBs) and Ub‐like proteases are attractive but challenging drug targets. We developed a high‐throughput synthesis method and prepared a 7536‐member cyanimide DUB‐targeted compound library in 1536‐well plates, using Echo acoustic dispensing. Screening yielded a selective, 35 nM inhibitor of mUSP18, the main ISG15 protease.
Raymond Kooij +8 more
wiley +2 more sources
Coxsackievirus B3, Shandong Province, China, 1990–2010
Emerging Infectious Diseases, 2012 To determine the cause of a 2008 outbreak of aseptic meningitis in Shandong Province, China, we analyzed samples from outbreak patients and coxsackievirus B3 samples collected during 1990–2010 surveillance. The cause of the outbreak was coxsackievirus B3,
Zexin Tao +9 more
doaj +1 more source
Expression of Concern: Blockade of interleukin-17A protects against coxsackievirus B3-induced myocarditis by increasing COX-2/PGE2 production in the heart [PDF]
Pathog Diseuropepmc +2 more sources
A Kidnapping Story: How Coxsackievirus B3 and Its Host Cell Interact.
Cellular Physiology and Biochemistry, 2019 Infections with Coxsackievirus B3 and other members of the enterovirus genus are a common reason for myocarditis and sudden cardiac death in modern society.
S. Peischard +4 more
semanticscholar +1 more source
Central nervous system infection following vertical transmission of Coxsackievirus B4 in mice [PDF]
, 2016 This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.Coxsackie B viruses (CV-B) are important pathogens associated with several central nervous system (CNS) disorders.
Aouni, M +9 more
core +1 more source