A Structural Investigation of the Interaction between a GC-376-Based Peptidomimetic PROTAC and Its Precursor with the Viral Main Protease of Coxsackievirus B3. [PDF]
De Santis A +9 more
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Expression of Concern: Blockade of interleukin-17A protects against coxsackievirus B3-induced myocarditis by increasing COX-2/PGE2 production in the heart. [PDF]
europepmc +1 more source
ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection. [PDF]
Bredow C +22 more
europepmc +1 more source
MicroRNA-22-3p displaces critical host factors from the 5' UTR and inhibits the translation of Coxsackievirus B3 RNA. [PDF]
Rani P +7 more
europepmc +1 more source
Replicase gene of coxsackievirus B3
A cDNA copy covering two-thirds of the coxsackievirus B3 genome was cloned in the PstI site of the pBR322 vector. A nucleotide sequence containing the gene for the viral replicase and the 3' noncoding region of the coxsackievirus B3 genome was determined.
P O, Stålhandske +2 more
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Genetics of coxsackievirus B3 cardiovirulence
European Heart Journal, 1995The human enteroviruses, especially the coxsackie B viruses, have been established as aetiologic agents of human inflammatory heart disease, a condition which may lead to dilated cardiomyopathy and heart failure. It is clear from murine models of coxsackievirus B3-induced inflammatory heart disease that not all strains of the virus are cardiovirulent ...
Steven Tracy +2 more
exaly +3 more sources
The entire nucleotide sequence of the coxsackievirus B3 strain Nancy (CB3) genome has been determined from cDNA. The genome is 7396 nucleotides long, and encodes a 2185 amino acid long polyprotein. It exhibits the same gene organization as other enterovirus genomes.
A M, Lindberg +2 more
openaire +2 more sources
COXSACKIEVIRUS B3 IN HUMAN MILK
The Pediatric Infectious Disease Journal, 2006Coxsackievirus B3 can cause severe neonatal disease with high mortality. We present the first report of detection of coxsackievirus B3 in the mothers' milk of 2 severely infected neonates by culture and reverse transcriptase-polymerase chain reaction. Reverse transcriptase-polymerase chain reaction is a rapid and sensitive tool to detect coxsackievirus
Mei-Ling, Chang +5 more
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The Structure of Coxsackievirus B3
1997Picornaviruses are small, nonenveloped, icosahedral viruses. The mature virions are approximately 300 A in diameter and the interior of the capsid shell is packed with single-stranded plus sense RNA (Mw ∼ 8×106 Daltons) (Rueckert 1990). The virus capsid is composed of 60 protomers, each consisting of one copy of the viral proteins VP1, VP2, VP3 and VP4
J K, Muckelbauer, M G, Rossmann
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Genetic Determinants of Coxsackievirus B3 Pathogenesis
Annals of the New York Academy of Sciences, 2002Abstract:The development of high throughput genomic and bioinformatic analysis tools, coupled with established molecular techniques, has allowed new insights into the pathogenesis of infectious diseases. In humans, coxasackievirus B3 (CVB3) is the primary etiological agent of viral myocarditis, an inflammatory disease process involving the heart muscle.
Bruce M, McManus +10 more
openaire +2 more sources

